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Li Ka Shing Institute of Virology

Publications

LKS Publications

[2017] [2016] [2015] [2014] [2013] [2012]  [2011]  [2010]

 

2017

 

Multiple PI

Marawan Ahmed, Horia H. Jalily, Aravindhan Ganesan, Michael Houghton and Khaled Barakat (2017) A Comprehensive Model of the Human Nav1.5 Sodium Channel: Structural and Mechanistic Insights of Ion Permeation & Drug Blockage. Drug Design, Development and Therapy (Accpeted)

 

Ding N, Craik SA, Pang X, Lee B, Neumann NF. (2017) Assessing UV Inactivation of Adenovirus 41 Using Integrated Cell Culture Real-Time qPCR/RT-qPCR. Water Environ Res. Apr 1;89(4):323-329

 

Hou, S. Kumar, A. Airo, A.M. Xu, Z. Stryapunina, I. Wong, C.P. Branton, W. Tchesnokov, E. Götte, M.

 

Power, C. Hobman, T.C.(2017). Zika virus hijacks stress proteins and modulates host stress response. Journal of Virology. JVI.00474-17. doi: 1

 

Shangmei Hou, Anil Kumar, Zaikun Xu, Adriana M. Airo, Iryna Stryapunina, Cheung Pang Wong, William Branton,

 

Egor Tchesnokov, Matthias Götte, Christopher Power, and Tom C. Hobman(2017) Zika Virus Hijacks Stress Granule roteins and Modulates the Host Stress Response J. Virol. August 91:16 21 Accepted manuscript posted online 7 June 2017 doi:10.1128/JVI.00474-17

 

Jovel, S. O’keefe, J. Patterson, M. Bording-Jorgensen, W. Wang, A. L. Mason, K. Warren, Gane Wong. (2017) Cerebrospinal fluid in a small cohort of patients with multiple sclerosis was generally free of microbial DNA.Frontiers in Cellular and Infection Microbiolog 6:article198 doi.org/10.3389/fcimb.2016.00198

 

Jovel, S. O’Keefe, J. Patterson, M. Bording-Jorgensen, W. Wang, A.L. Mason, K.G. Warren, G.K. Wong. (2017) Cerebrospinal fluid in a small cohort of patients with multiple sclerosis was generally free of microbial DNA. Front. Cell. Infect. Microbiol. 6: 198. PMID: 28111617. DOI: 10.3389/fcimb.2016.00198

 

Limonta, D. *Jovel, J. *Kumar, A. Hou, S. Airo, A.M. Branton, W. Wong, G.K-S. Mason, A. Power, C.

 

Kim A, Robbins JB, Dreux M, Cogburn KE, Giang E, Ball JK, Abrignani S, Yuen M, Lewis-Ximenez LL, Lauer G, Pockros P, Tyrrell DLJ, Kneteman NM, Law M.  (2017) The hepatitis C virus host receptor CD81 is an autoantigen in chronic viral hepatitis patients.  Journal of Virology SUBMITTED January 2017

 

Michael Logan, John Law, Jason Alexander Ji-Xhin Wong, Darren Hockman, Amir Landi, Chao Chen, CrCrcrawfordCrawford, Kevin Crawford, Juthika Kundu, Lesley Baldwin, Janelle Johnson, Anita Dahiya, Gerald LaChance, Joseph Marcotrigiano, Mansun Law, Steven Foung, Lorne Tyrrell, and Michael Houghton (2017) Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG. J. Virol. January 91:1 14 doi:10.1128/JVI.01552-16

 

N.S. Pagadala, K. Sahu, R. Bhat, K. Syed, M. Houghton and J.A. Tuszynski (2017) In silico Strategies for Designing Anti-prion Compounds, Expert Opinion on Drug Discovery, 2017 Mar;12(3):241-248. doi: 10.1080/17460441.2017.1287171. Epub 2017 Feb 2. Review. PMID: 28118747

 

Potts, K.G., Irwin, C.R., Favis, N.A., Pink, D.B., Vincent, K.M., Lewis, J.D., Moore, R.B., Hitt, M.H., and Evans, D.H. (2017) Oncolytic vaccinia virus deleted in the small subunit of ribonucleotide reductase for the treatment of bladder cancer. EMBO Molecular Medicine e201607296. doi: 10.15252/emmm.201607296

 

Potts, K.G., Irwin, C.R., Favis, N.A., Pink, D.B., Vincent, K.M., Lewis, J.D., Moore, R.B., Hitt, M.M.*, Evans, D.H.* (2017) Deletion of F4L (ribonucleotide reductase) in vaccinia virus produces a selective oncolytic virus and promotes anti-tumor immunity with superior safety in bladder cancer models. EMBO Mol Med. May;9(5):638-654 *both authors contributed equally

 

Robinson J, Aseal, Hawkes M, Pedsdoc, Noga M, Preiksaitis JK, Mabilangan C (2017) Radiation  exposure from diagnostic imaging in a cohort of pediatric transplant recipients. PONE-D-16-22954R1, PLOS One Jan 12. doi 10.1371/journal.pone.0.167922

 

Santer DM, Minty GE, Mohamed A, Baldwin L, Bhat R, Joyce M, Egli A, Tyrrell DLHoughton M. (2017) A novel method for detection of IFN-lambda 3 binding to cells for quantifying IFN-lambda receptor expression. J Immunol Methods. doi:10.1016/j.jim.2017.03.001.

 

Santer D, Baldwin L, Tyrrell DLJ, Mohamed A, Houghton M, Joyce M, Minty G, Bhat R, Egli A.  (2017) A novel method for detection of IFN-lambda 3 binding to cells for quantifying IFN-lambda receptor expression.  J Immunol Methods. 2017 Mar 5. pii: S0022-1759(17)30004-2. doi: 10.1016/j.jim.2017.03.001. [Epub ahead of print]

 

Sarhan M, Abdel-Hakeem M, Mason A, Tyrrell DLJ, Houghton M.  Glycogen synthase kinase 3ß inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism.  Nature Scientific Reports Published Online May 31, 2017

 

Mohammed A. Sarhan, Mohamed S. Abdel-Hakeem, Ishwar Hossmani, Lorne Tyrrell, Andrew Mason and Michael Houghton. (2017) GSK3b inhibitors prevent HCV release/assembly through perturbation of lipid Tong Y, Pang X, Mabilangan C, Preiksaitis JK  (2017)   Determination of the Biological Form of Human Cytomegalovirus DNA in the Plasma of Solid-Organ Transplant Recipients. J Infect metabolism Nature Scientific Reports: in press

 

Sheff JG, Farshidfar F, Bathe OF, Kopciuk K, Gentile F, Tuszynski J, Barakat K, Schriemer DC. (2017) Novel Allosteric Pathway of Eg5 Regulation Identified through Multivariate Statistical Analysis of Hydrogen-Exchange Mass Spectrometry (HX-MS) Ligand Screening Data. Mol Cell Proteomics. Mar;16(3):428-437. doi: 10.1074/mcp.M116.064246. Epub 2017 Jan 5. PMID: 28062800

 

Tong Y, Pang XL, Mabilangan C, Preiksaitis JK. (2017) Determination of the Biological Form of Human Cytomegalovirus DNA in the Plasma of Solid-Organ Transplant Recipients. J Infect Dis. Apr 12. doi: 10.1093/infdis/jix069. [Epub ahead of print]

 

Turvey SL, Tyrrell GJ, Hernandez C, Kabbani D, Doucette K, Cervera C. (2017) Mycobacterium branderi infection: Case report and literature review of an unusual and difficult-to-treat non-tuberculous mycobacterium. Int J Infect Dis. 2017 May;58:65-67. doi: 10.1016/j.ijid.2017.03.002. Epub 2017 Mar 6. PMID: 28268125

 

Yao Q, Fischer K, Tyrrell DLJ, Gutfreund K. (2017) The Pekin duck programmed death-1 receptor:  cDNA cloning, genomic organization and expression analysis.  International J Immunogentics.  SUBMITTED March 2017

 

 

Individual Publications

Ablenas CJ, Liu HW, Shkriabai N, Kvaratskhelia M, Cosa G, Götte M. (2017) Dynamic Interconversions of HCV Helicase Binding Modes on the Nucleic Acid Substrate.  ACS Infect Dis. Jan 13;3(1):99-109. doi: 10.1021/acsinfecdis.6b00177.

 

Acharya, J. Alexandre, J. Bernabeu, M. Campbell, S. Cecchini, J. Chwastowski, Y. Cho, M. de Montigny, D. Derendarz, A. De Roeck, J. R. Ellis, M. Fairbairn, D. Felea, M. Frank, D. Frekers, G. Giacomelli, M. Giorgini, D. Hasegan, T. Hott, J. Jakubek, A. Katre, D-W Kim, M.G.L. King, K. Kinoshita, D. Lacarrere, S. C. Lee C. Leroy, A. Margiotta, N. Mauri, N. E. Mavromatos, P. Mermod, V. A. Mitsou, R. Orava, L. Pasqualini, L. Patrizii, G. E. Pavalas J. L. Pinfold, M. Platkevic V. Popa, M. Pozzato, S. Pospisil, A. Rajantie, Z. Sahoun, M. Sakellariadou, S. Sarkar, G. Semenoff, G. Sirri, K. Sliwa, R. Soluk, M. Spurio, R. Staszewski, J. Swain, M. Tenti, V. Togo, M. Trzebinski, J. A. Tuszynski, V. Vento, O. Vives, Z. Vykydal, and A. Widom (2017)  Search for magnetic monopoles with the MoEDAL forward trapping detector in 13 TeV proton-proton collisions at the LHC, Physical Review Letters 118 no.6, 061801

 

Airo, A. *Urbanowski, M.D. Lopez-Orozco, J. You, J. Skene-Arnold, T.D. Holmes, C. Malik-Soni, N. Frappier, L. Hobman, T.C. *Authors contributed equally. (2017). Expression of Flavivirus capsids enhance the cellularenvironment for viral replication by activating Akt-signalling pathways. Cellular Microbiology.

 

Alhhazmi A, Pandey A, Tyrrell GJ. (2017) Identification of the Group B Streptococcus Capsule Type using a Dual Phenotypic/Genotypic Assay. J Clin Microbiol. Jun 14. pii: JCM.00300-17. doi: 10.1128/JCM.00300-17. [Epub ahead of print] PMID: 28615470

 

Arroyo-Arroyo, M., Arango, E., Carmona-Fonseca, J., Aristizabal, B., Yanow, S.K., Maestre, A. (2017) Efficacy of different primaquine regimens to control Plasmodium falciparum gametocytemia in Colombia.  Am. J. Trop. Med. Hyg. In press.

 

Aur and J.A. Tuszynski, (2017) The Emergence of Structered, Living and Conscious Matter in the Evolution of the Universe: A Theory of Structural Evolution and Interaction of Matter, In: Habitability of the Universe Before Earth [in series: Astrobiology: Exploring Life on Earth and Beyond, eds. Pabulo Henrique Rampelott, JosephSeckbach & Richard Gordon]. Ed.: R. Gordon & A.A. Sharov. Amsterdam, Elsevier B.V

 

Balzarini J, Menni M, Das K, va Berckelaer L, Ford A, Maguire NM, Liekens S, Boehmer PE, Arnold E, Götte M, Maguire AR  (2017) Guanine α-carboxy nucleoside phosphonate (G-α-CNP) shows a different inhibitory kinetic profile against the DNA polymerases of human immunodeficiency visrus (HIV) and herpes viruses.  Biochem Pharmacol. Jul 15;136:51-61. Doi: 10.1016/j.bcp.2017.04.001 Epub 2017 Apr 6

 

Barzanjeh, V. Salari, J.A. Tuszynski, M. Cifra and C. Simon (2017) An Optomechanical Proposal for Monitoring Microtubule Mechanical Vibrations, Physical Review E (revisions)

 

Barker KR, Lu Z, Kim H, Zheng Y, Chen J, Conroy AL, Hawkes M, Cheng HS, Njock MS, Fish JE, Harlan JM, López JA, Liles WC, Kain KC. (2017)  miR-155 Modifies Inflammation, Endothelial Activation and Blood-Brain Barrier Dysfunction in Cerebral Malaria. Mol Med. Feb 2;23. doi: 10.2119/molmed.2016.00139

 

Bral M, Gala-Lopez B, Bigam D, Kneteman N, Malcolm A, Livingstone S, Andres A, Emamaullee J, Russell L, Coussios C, West LJ, Friend PJ, Shapiro AM. (2017) Preliminary  Single-Center Canadian Experience of Human Normothermic Ex Vivo Liver Perfusion:  Results of a Clinical Trial. Am J Transplant. 2017 Apr;17(4):1071-1080. doi: 10.1111/ajt.14049. Epub 2016 Dec 9. PubMed PMID: 27639262.

 

Capitanio, J.S., B. Montpetit, and R. W. Wozniak. (2017). Human Nup98 regulates the localization  and  activity  of  DExH/D-box  helicase  DHX9.  e-Life.  6:e18825.  DOI: 10.7554/eLife.18825.

 

Cervera C, Sanroma P, González-Ramallo V, García de la María C, Sanclemente G, Sopena N, Pajarón M, Segado A, Mirón M, Antón F, Basterretxea A, Cuende A, Miró JM; DAPTODOM Investigators.. (2017) Safety and efficacy of daptomycin in outpatient parenteral antimicrobial therapy: a prospective and multicenter cohort study (DAPTODOM trial). Infect Dis (Lond). Mar;49(3):200-207.

 

Cocchi, C. Minuto, L. Tonello, F. Gabrielli, G. Bernroider, M. Rasenick, J. A. Tuszynski and F. Cappello (2017) Linoleic acid: is this the key that unlocks the quantum brain?, BMC Neuroscience 18:38

 

Eaton, H., Dermody, T., Johnston, R., Jais, P., Shmulevitz, M. (2017) African swine fever virus NP868R capping enzyme promotes reovirus rescue during reverse genetics by promoting reovirus protein expression, virion assembly, and RNA incorporation into infectious virions J.Virology, Accepted manuscript posted online 15 March 2017 doi:10.1128/JVI.02416-16

 

Eyre NS, Aloia AL, Joyce MA, Chulanetra M, Tyrrell DLJ, Beard MR.  (2017) Sensitive luminescent reporter viruses reveal appreciable release of hepatitis C virus NS5A protein into the extracellular environment.  Virology April 7;507:20-30 doi 10.1016/j.virol.2017.04.003

 

Feld JJ, Ramji A, Shafran S, Willlems B, Marotta P, Huchet E, Vachon M-L, Svarovskaia ES, Huang KC, Hyland RH, Yun C, Brainard DM, McHutchison JG, Tam E, Bailey R, Cooper C, Yoshida E, Greenbloom S, Elkhashab M, Borgia S, Swain M. (2017) Ledipasvir-sofosbuvir plus ribavirin in treatment-naïve patients with HCV genotype 3 infection: an open-label study. Clin Infect Dis. May 23 [Epub ahead of print].

 

Freedman H, Logan MR, Hockman D, Leman JK,, Law JL, Houghton M. (2017) Computational prediction of the heterodimeric and higher order structure of gpE1/gpE2 envelope glycoproteins encoded by the hepatitis C virus (HCV). J Virol.  doi: 10.1128/JVI.02309-16.

 

Freedman SB, Eltorki M, Chui L, Xie J, Feng S, MacDonald J, Dixon A, Ali S, Louie M, Lee BE, Osterreicher L, Thull-Freedman J. (2017) Province-Wide Review of Pediatric Shiga Toxin-Producing Escherichia coli Case Management. J Pediatr. Jan;180:184-190.e1. doi: 10.1016/j.jpeds.2016.09.013. Epub 2016 Oct 10.

 

Ganesan, A.; Coote, M. L.Barakat, K. (2017) Molecular ‘time‐machines’ to unravel key biological events for drug design. Wiley Interdisciplinary Reviews: Computational Molecular Science 2017.

 

Ganesan, A.Barakat, K. (2017) Applications of computer-aided approaches in the development of hepatitis C antiviral agents. Expert Opinion on Drug Discovery 2017, 12, 407-425.

 

Gavina, K., Arango, E., Larrotta, C.A., Maestre, A., Yanow, S.K. (2017) A sensitive species-specific reverse transcription real-time PCR method for detection of Plasmodium falciparum and Plasmodium vivax. Parasite Epidemiology and Control. In press.

 

P.E. Ghaly, C.D.M. Churchill, R.M. Abou-El Magd, Z. Hajkova, P. Draber, F.G. West and J.A. Tuszynski  (2017) Synthesis and Biological Evaluation of Structurally Simplified Noscapine Analogues as Microtubule Binding Agents, Canadian Journal of Chemistry (accepted Feb. 15, 2017)

 

Gidi Y, Götte M, Cosa G. (2017) Conformational Changes Spanning Angstroms to Nanometers via a Combined Protein Induced Fluorescence Enhancement-Förster Resonance Energy Transfer Method.   J Phys Chem B. Feb 8. doi: 10.1021/acs.jpcb.6b11495. [Epub ahead of print] PMID: 28177636

 

E.G. Govorunova, O.A. Sineshchekov, E.M. Rodarte, R. Janz, O. Morelle, M. Melkonian, G.K. Wong, J.L. Spudich. (2017) The expanding family of natural anion channelrhodopsins reveals large variations in kinetics, conductance, and spectral sensitivity. Sci. Rep. 7: 43358. PMID: 28256618. DOI: 10.1038/srep43358

 

Grasso; J.A. Tuszynski, U. Morbiducci, G. Licandro, A. Danani, M.A. Deriu (2017) Thermodynamic and Kinetic Stability of the Josephin Domain Closed Arrangement: Evidences from Replica Exchange Molecular Dynamics, Biol Direct. 2 Jan 19;12(1):2. doi: 10.1186/s13062-016-0173-y. PMID: 28103906

 

Cameron Griffiths, Steven Drews* and David J. Marchant*. (2017) Respiratory Syncytial Virus Infection, Detection and New Options for Prevention and Treatment. Clinical Microbiology Reviews (impact factor = 17.4). Jan; 30(1):277-319. Review.

 

Gudiol C, Royo-Cebrecos C, Tebe C, Abdala E, Akova M, Álvarez R, Maestro-de la Calle G, Cano A, Cervera C, Clemente WT, Martín-Dávila P, Freifeld A, Gómez L, Gottlieb T, Gurguí M, Herrera F, Manzur A, Maschmeyer G, Meije Y, Montejo M, Peghin M, Rodríguez-Baño J, Ruiz-Camps I, Sukiennik TC, Carratalà J; BICAR study group. (2017)  Clinical efficacy of β-lactam/β-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum β-lactamase-producing Enterobacteriaceae in haematological patients with neutropaenia: a study protocol for a retrospective observational study (BICAR). BMJ Open. Jan 23;7(1):e013268.

 

Gudiol C, Royo-Cebrecos C, Abdala E, Akova M, Álvarez R, Maestro-de la Calle G, Cano A, Cervera C, Clemente WT, Martín-Dávila P, Freifeld A, Gómez L, Gottlieb T, Gurguí M, Herrera F, Manzur A, Maschmeyer G, Meije Y, Montejo M, Peghin M, Rodríguez-Baño J, Ruiz-Camps I, Sukiennik TC, Tebe C, Carratalà J; BICAR study group. Efficacy of β-lactam/β-lactamase inhibitor combinations for the treatment of bloodstream infection due to extended-spectrum β-lactamase-producing Enterobacteriaceae in hematological patients with neutropenia. Antimicrob Agents Chemother. 2017 Jun 5. pii: AAC.00164-17. doi: 10.1128/AAC.00164-17. [Epub ahead of print]

 

Hackenberg, M.R. McKain, S.G. Lee, S.R. Choudhury, T. McCann, S. Schreier, A. Harkess, J.C. Pires, G.K. Wong, J.M. Jez, et al. [Epub ahead of print] Gα and regulator of G-protein signaling (RGS) protein pairs maintain functional compatibility and conserved interaction interfaces throughout evolution despite frequent loss of RGS proteins in plants. New Phytol. PMID: 27634188. DOI: 10.1111/nph.14180

 

J.D. Han, X. Li, C.K. Jiang, G.K. Wong, C.J. Rothfels, G.Y. Rao. (2017). Evolutionary analysis of the LAFL genes involved in the land plant seed maturation program. Front. Plant Sci. 8: 439. PMID: 28421087. DOI: 10.3389/fpls.2017.00439

 

Hobman, T.C. (2017). Astrocytes from human fetal brain are highly permissive for Zika virus replication and persistence. mBio.

 

Horia H. Jalily and Khaled Barakat (2017) Homology Modeling: An Overview of Fundamentals and Tools”, International Review on Modelling and Simulations (IREMOS) (Accepted)

 

Jacobson IM, Lawitz E, Gane EJ, Willems BE, Ruane PJ, Nahass RG, Borgia SM, Shafran SD, Workowski KA, Pearlman B, Hyland RH, Stamm LM, Svarovskaia E, Dvory-Sobol H, Zhu Y, Subramanian GM, Brainard DM, McHutchison JG, Bräu N, Berg T, Agarwal K, Bhandari BR, Davis M, Feld JJ, Dore GJ, Stedman CA, Thompson A, Asselah T, Roberts S, Foster GR. (2017) Efficacy of 8 weeks of sofosbuvir, velpatasvir, and voxilaprevir in patients with chronic HCV infection: 2 phase 3 randomized trials. Gastroenterology. Apr 5 [Epub ahead of press]. \

 

K.L. Johnson, A.M. Cassin, A. Lonsdale, G.K. Wong, D.E. Soltis, N.W. Miles, M. Melkonian, B. Melkonian, M.K. Deyholos, J. Leebens-Mack, et al. (2017). Insights into the evolution of hydroxyproline-rich glycoproteins from 1000 plant transcriptomes. Plant Physiol. 174: 904-921. PMID: 28446636. DOI: 10.1104/pp.17.00295

 

Johnson, I.S. Goping, A. Rieger, J. Mane, T. Huzil, A. Banerjee, R.F. Luduena, B. Hssani, P. Winter and J.A. Tuszynski (2017) Novel Colchicine Derivatives and Their Anti-Cancer Activity (accepted July 6, 2016), Current Topics in Medicinal Chemistry 17(22):2538-2558. doi: 10.2174/1568026617666170104143618.

 

Kalyaanamoorthy, S.Barakat, K. H. (2017) Development of Safe Drugs: The hERG Challenge. Medicinal Research Reviews 2017.

 

Karvellas CJ, Cardoso FS, Senzolo M, Wells M, Alghanem MG, Handou F, Kwapisz L, Kneteman NM, Marotta PJ, Al-Judaibi B. (2017) Clinical Impact of Portal Vein Thrombosis Prior to Liver Transplantation: A Retrospective Cohort Study. Ann Hepatol. March-April;16(2):236-436. doi: 10.5604/16652681.1231582. PubMed PMID: 28233745.

 

Kwo P, Gane E, Peng C-Y, Pearlman B, Vierling JM, Serfaty L, Buti M. Shafran S, Stryszak P, Lin L, Gress J, Black S, Dutko FJ, Robertson M, Wahl J, Lupinacci L, Barr E, Haber B. (2017) Effectiveness of elbasvir and grazoprevir combination, with or without ribavirin, for treatment-experienced patients with chronic hepatitis C infection. Gastroenterology 152:164-75.

 

Lapetina, D. L., C. Ptak, U. K. Roesner, and R. W. Wozniak. (2017). Yeast Sir4 and a subset of nucleoporins form a complex distinct from nuclear pore complexes. In revision for the J Cell Biol.

 

Leligdowicz A, Conroy AL, Hawkes M, Zhong K, Lebovic G, Matthay MA, Kain KC. (2017) Validation of two multiplex platforms to quantify circulating markers of inflammation and endothelial injury in severe infection. PLoS One. Apr 18;12(4):e0175130. doi: 10.1371/journal.pone.0175130. eCollection 2017.

 

C.S. Lin, J.J. Chen, C.C. Chiu, H.C. Hsiao, C.J. Yang, X.H. Jin, J. Leebens-Mack, C.W. dePamphilis, Y.T. Huang, L.H. Yang, G.K. Wong et al. (2017). Concomitant loss of NDH complex-related genes within chloroplast and nuclear genomes in some orchids. Plant J. 90: 994-1006. PMID: 28258650. DOI: 10.1111/tpj.13525

 

López-Aladid R, Guiu A, Sanclemente G, López-Medrano F, Cofán F, Mosquera MM, Torre-Cisneros J, Vidal E, Moreno A, Aguado JM, Cordero E, Martin-Gandul C, Pérez-Romero P, Carratalá J, Sabé N, Niubó J, Cervera C, Cervilla A, Bodro M, Muñoz P, Fariñas C, Codina MG, Aranzamendi M, Montejo M, Len O, Marcos MA; Group for Study of Infection in Transplantation of the Spanish Society of Infectious Diseases Clinical Microbiology GESITRA-SEIMC Spanish Network for Research in Infectious. (2017) Detection of cytomegalovirus drug resistance mutations in solid organ transplant recipients with suspected resistance. J Clin Virol. May; 90:57-63

 

Ma C, Claude KM, Kibendelwa ZT, Brooks H, Zheng X, Hawkes M. (2017) Pathog Glob Health. Is maternal education a social vaccine for childhood malaria infection? A cross-sectional study from war-torn Democratic Republic of Congo. Feb 21:1-9. doi: 10.1080/20477724.2017.1288971.

 

Marrie TJ, Tyrrell GJ, Majumdar SR, Eurich DT. (2017) Concurrent Infection with Hepatitis C Virus and Streptococcus pneumoniae. Emerg Infect Dis. Jul;23(7):1118-1123. doi: 10.3201/eid2307.161858. PMID: 28628455

 

Martin LJ, Im C, Dong H, Lee BE, Talbot J, Meurer DP, Mukhi SN, Drews SJ, Yasui Y. (2017) Influenza-like illness-related emergency department visits: Christmas and New Year holiday peaks and relationships with laboratory-confirmed respiratory virus detections, Edmonton, Alberta, 2004-2014. Influenza Other Respir Viruses. Jan; 11(1):33-40. doi: 10.1111/irv.12416. Epub 2016 Aug 30. PMID: 27442911

 

McDonald CR, Conroy AL, Hawkes M, Elphinstone RE, Gamble JL, Hayford K, Namasopo S, Opoka RO, Liles WC, Kain KC. (2017) Brain-Derived Neurotrophic Factor is Associated with Disease Severity and Clinical Outcome in Ugandan Children Admitted to Hospital with Severe Malaria. Pediatr Infect Dis J. Feb;36(2):146-150. doi: 10.1097/INF.0000000000001382.

 

Meng G, Tang X, Yang Z, Benesch MGK, Marshall A, Murray D, Hemmings DG, Wuest F, McMullen TP W, and Brindley D N (2017) Implications for breast cancer treatment from increased autotaxin production in adipose tissue after radiotherapy,” FASEB journal May 24. pii: fj.201700159R. doi: 10.1096/fj.201700159R. [Epub ahead of print]

 

A Montano-Loza, R. Bhanji, A. Mason. (2017) Systematic Review: Recurrent autoimmune liver diseases after liver transplantation. Alimentary Pharmacology & Therapeutics 45: 485–500. doi:10.1111/apt.13894

 

Nabwire J, Namasopo S, Hawkes M. (2017) Oxygen Availability and Nursing Capacity for Oxygen Therapy in Ugandan Paediatric Wards. J Trop Pediatr. May 8. doi: 10.1093/tropej/fmx033. [Epub ahead of print]

 

Nayebi N, Cetinel S, Omar SI, Tuszynski JA, Montemagno C. (2017) A computational method for selecting short peptide sequences for inorganic material binding.

 

Osiowy, K. Fonseca, A. Mason, A. Andonov, K. Swidinsky, E. Giles, C. Coffin. (2017) Transmission of hepatitis D virus between spouses: a longitudinal study of the first reported Canadian case. Infectious Disease Cases: in press.

 

Pagadala NS, Syed K, Tuszynski J. (2017) Software for molecular docking: a review. Biophys Rev. Apr;9(2):91-102. doi: 10.1007/s12551-016-0247-1. Epub 2017 Jan 16. Review.

 

N.S. Pagadala, K. Syed and J.A. Tuszynski (2017) Software for Molecular Docking: A Review. Biophys Rev. Apr;9(2):91-102. doi: 10.1007/s12551-016-0247-1. Epub 2017 Jan 16. PMID: 28510083

 

R.J. Paproski, J. Jovel, G.K. Wong, J.D. Lewis, R.J. Zemp. (2017) Enhanced detection of cancer biomarkers in blood-borne extracellular vesicles using nanodroplets and focused ultrasound. Cancer Res. 77: 3-13. PMID: 27793845. DOI: 10.1158/0008-5472.CAN-15-3231; Dis. 2017 Apr 12. Doi 10.1093/infdis/jix069

 

Pericàs JM, Messina JA, Garcia-de-la-Maria C, Park L, Sharma-Kuinkel BK, Marco F, Wray D, Kanafani Z, Carugati M, Durante-Mangoni E, Tattevin P, Chu VH, Moreno A, Fowler VG Jr, Miró JM; International Collaboration on Endocarditis Microbiology- Investigators (Cervera C). (2017)  Influence of Vancomycin Minimum Inhibitory Concentration on the Outcome of Methicillin-Susceptible Staphylococcus aureus Left-Sided Infective Endocarditis Treated with Anti-staphylococcal Beta-Lactam Antibiotics; a Prospective Cohort Study by the International Collaboration on Endocarditis. Clin Microbiol Infect. Jan 31. pii: S1198-743X(17)30050-2.

 

Ptak, C. and R.W. Wozniak. (2017). SUMO and Nucleocytoplasmic Transport. Adv Exp Med Biol. 963:111-126. doi: 10.1007/978-3-319-50044-77

 

Reid, CR Hobman, TC. (2017). The nucleolar helicase DDX56 distributes to West Nile virus assembly sites. Virology. 500: 169-177.

 

E.A. Rietman, J.G. Scott, J.A. Tuszynski and G.Lakka Klement (2017) Personalized Anticancer Therapy Selection Using Molecular Landscape Topology and Thermodynamics, Oncotarget  Mar 21;8(12):18735-18745. doi: 10.18632/oncotarget.12932.

 

Santelices, D.E. Friesen, C. Bell, J. Lewis, J. Xiao, C.M. Hough, H. Freedman, V. Rezania, K. Shankar and J.A. Tuszynski (2017) Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic Solutions, Scientific Reports (corrections February 24, 2017)

 

Seal A, Hawkes M, Bhargava R, Noga M, Preiksaitis J, Mabilangan C, Robinson J. Radiation (2017) Exposure from Diagnostic Imaging in a Cohort of Pediatric Transplant Recipients. PLoS One. Jan 12;12(1):e0167922. doi: 10.1371/journal.pone.0167922.

 

Sheff, J. G.; Farshidfar, F.; Bathe, O. F.; Kopciuk, K.; Gentile, F.; Tuszynski, J.; Barakat, K.Schriemer, D. C. (2017) Novel Allosteric Pathway of Eg5 Regulation Identified through Multivariate Statistical Analysis of Hydrogen-Exchange Mass Spectrometry (HX-MS) Ligand Screening Data. Molecular & Cellular Proteomics, mcp. M116. 064246

 

J.G. Sheff, F. Farshidfar, O.F. Bathe, K. Kopciuk, F. Gentile, K. Barakat and D.C. Schriemer (2017) Novel allosteric pathway of Eg5 regulation identified through multivariate statistical analysis of HX-MS ligand screening data., Molecular Cell Proteomics, Jan. 5 doi: 10.1074/mcp.M116.064246

 

Spasevska I, Ayoub AT, Winter P, Preto J, Wong GK, Dumontet C, Tuszynski JA. (2017) Modeling the Colchicum autumnale Tubulin and a Comparison of Its Interaction with Colchicine to Human Tubulin. Int J Mol Sci. Aug 2;18(8). pii: E1676. doi: 10.3390/ijms18081676. PMID: 28767055

 

Sperling JL, KL Silva-Brandao, MM Brandao, VK Lloyd, S Dang, CS Davis, FA Sperling and KE Magor (2017) Comparison of bacterial 16S rRNA variable regions for microbiome surveys of ticks.  Ticks and Tickborne Diseases, 8 (4): 453-461.

 

Steenbergen R, Oti M, Ter Horst R, Tat W, Neufeldt C, Belovodskiy A, Chua TT, Anwar-Mohamed A, Cho WJ, Joyce MA, Dutilh B, Tyrrell DLJ.  (2017) Establishment of normal hepatocyte metabolism and functions in hepatoma cells by adult human serum.  Cell Metabolism SUBMITTED May 2017

 

Taylor, B.J., Lanke, K., Banman, S.L., Morlais, I., Morin, M.J., Bousema, T., Rijpma, S.R., Yanow, S.K. (2017) A Direct from Blood Reverse Transcriptase Polymerase Chain Reaction Assay for Monitoring Falciparum Malaria Parasite Transmission in Elimination Settings. Am. J. Trop. Med. Hyg. In press.

 

Teferi, W.M., Desaulniers, M.A., Noyce, R.S., Shenouda, M., Umer, B., and Evans, D.H. (2017) The vaccinia virus K7 protein promotes histone methylation associated with heterochromatin formation. PLoS One. 12(3):e0173056: 1-21.

 

Tonello, M. Cocchi, F. Gabrielli and J.A. Tuszynski (2017) Stream of Consciousness: Quantum and Biochemical Assumptions Regarding Psychopathology, Medical Hypotheses Volume 101, April; 78-84

 

J.A. Tuszynski, T. Luchko, P. Winter, C. Churchill, K. Sahu, F. Gentile, S.I. Omar, N. Nayebi, G. Hu, K. Wang and J. Ruan. (2017) Molecular Dynamics and Related Computational Methods with Applications to Drug Discovery, in “Coupled Mathematical Models for Physical and Biological Nanoscale Systems and Their Applications” (L.L. Bonilla, E. Kaxiras and R. Melnik, ed.), Springer, Berlin

 

Vanpouille C, Bernatchez JA, Lisco A, Arakelyan A, Saba E, Götte M, Margolis L.  (2017) A common anti CMV drug, ganciclovir, inhibits HIV-1 replication in human tissues ex vivo.  AIDS  May 5, doi 10.1097/QAD.0000000000001532. [Epub ahead of print]

 

K.Velpula, M. R. Guda, K. Sahu, J.A. Tuszynski, S. Asuthkar, S. E. Martin, J. D. Lathia, and A. J. Tsung (2017) Metabolic targeting of EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma, Oncotarget (accepted February 28, 2017)

 

Vink, E.I., Smiley, J.R., and Mohr, I. (2017) Subversion of host responses to energy insufficiency by Us3 supports HSV-1 replication during stress. J. Virol. July; 91:14 13 Accepted manuscript posted online 3 May doi:10.1128/JVI.00295-17

 

Vrancken B, Adachi D, Benedet M, Singh A, Read R, Shafran S, Taylor GD, Houston S, Simmonds K, Plitt S, Sikora C, Lemey P, Charlton CL, Tang JW. (2017) Infect Genet Evol 52:100-105.

 

Wang, H. Zhang, X. Wang, J. Patterson, P. Winter, K. Graham, S. Ghosh, J.C. Lee, C.D. Katsetos, J.R. Mackey, G.K. Wong et al. (2017). Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer. Protoplasma 254: 1163-1173. PMID: 27943021. DOI: 10.1007/s00709-016-1060-1

 

Weismüller, P. Trivedi, A. Bergquist, M. Imam, H. Lenzen, C. Ponsioen, K. Holm, D. Gotthardt, M. Färkkilä, H. Marschall, D. Thorburn, R. Weersma, J. Fevery, T. Mueller, O. Chaouillères, K. Schulze, K. Lazaridis, S. Almer, S. Pereira, C. Levy, A. Mason, S. Naess, C. Bowlus, A. Floreani, E. Halilbasic, K. Yimam, P.Milkiewicz, U. Beuers, D. Huynh, A. Pares, C. Manser, G. Dalekos, B. Eksteen, P. Invernizzi, C. Berg, G. Kirchner, C. Sarrazin, V. Zimmer, L. Fabris, F. Braun, M. Marzioni, B. Juran, K. Said, C. Rupp, K. Jokelainen, M. Benito de Valle, F. Saffioti, A. Cheng, M. Trauner, C. Schramm, R. Chapman, T. Karlsen, E. Schrumpf, C. Strassburg, M.Manns, K. Lindor, G. Hirschfield, B. Hansen, M. Boberg on behalf of the International PSC Study Group. (2017) Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis. Gastroenterology in press

 

Julian Wei-Tze Tang, MBChB, PhD, MRCP, FRCPath; Marion Koopmans, PhD; Tommy T Lam, PhD; Hassan Zaraket, PhD; W. Ian Lipkin, MD; Jean-Michel Heraud, PhD; Asha M Abraham, MD, PhD; Amal Baraket, PhD; Seweryn Bialasiewicz, PhD; Miguela Caniza, MD; Paul K Chan, MD (CUHK), FRCPath, FHKCPath, FHKAM; Cheryl Cohen, MBBCh, FCPath (SA) Micro, DTM&H, MSc; André Corriveau, MD, MBA, FRCPC; Benjamin J Cowling, PhD; Steven J Drews, PhD, FCCM D(ABMM); Marcela Echavarria, PhD; Ron Fouchier, PhD; Pieter L Fraaij, MD, PhD; Hamid Jalal, PhD, FRCPath; Lance Jennings, PhD; Alice Kabanda, BSc; Herve A Kadjo, MD; Mohammed R Khanini, MBBS, MPhil, PhD,FCPath; Evelyn S Koay, PhD, FAACB, FRCPath; Mel Krajden, MD, FRCPC; Julius Lutwama, PhD; David J. Marchant, PhD; Hidekazu Nishimura, MD, PhD; Benjamin A Pinsky, MD, PhD; Sanjiv Rughooputh, PhD; Taslimarif Saiyed, PhD; Anita Shet, MD; Theo Sloots, BSc, PhD, GCM, MASM; JJ Muyembe Tamfum, MD, PhD; Sarah Tozer, PhD; Florette Treurnicht, PhD; Matti Waris, PhD; Aripuana Watanabe, PhD; Emile O Wemakoy, MD, PhD. (2017) The global epidemiology of non-influenza respiratory viruses – data gaps and a growing need. Lancet Infectious Diseases (impact factor = 21.4), 2017 Apr 28. pii: S1473-3099(17)30238-4. doi: 10.1016/S1473-3099(17)30238-4. [Epub ahead of print].

 

Willows, D. Skene-Arnold, T. Holmes, C.F.B. Hobman, T.C.(2017). A Protein Phosphatase-1 binding site in the Rubella virus capsid is important for viral replication. Virology.

 

Wyles D, Mangia A, Cheng W, Shafran S, Schwabe C, Ouyang W, Hedskog C, McNally J, Brainard DM, Doehle B, Svarovskaia V, Miller MD, Mo H, Dvory-Sobol H. (2017) Long-term persistence of HCV NS5A resistance associated substitutions after treatment with NS5A inhibitor ledipasvir. Antiviral Therapy  [in press].

 

Xu, Z. Asahchop, E. Brandon, W. Gilman, B.B. Power, C. Hobman, T.C.(2017). MicroRNAs upregulated during HIV infectiontarget peroxisome biogenesis factors: Implications for virus biology, diseasemechanisms and neuropathology. PLoS Pathogens. Jun 8;13(6):e1006360

 

Yang AS, Lopaticki S, O’Neill MT, Erickson SM, Douglas DN, Kneteman NM, Boddey JA. (2017) AMA1 and MAEBL are important for Plasmodium falciparum sporozoite infection of the liver. Cell Microbiol. Mar 31. doi: 10.1111/cmi.12745. [Epub ahead of print] PubMed PMID: 28371168.

 

Yang AS, O’Neill MT, Jennison C, Lopaticki S, Allison CC, Armistead JS, Erickson SM, Rogers KL, Ellisdon AM, Whisstock JC, Tweedell RE, Dinglasan RR, Douglas DN, Kneteman NM, Boddey JA. (2017) Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice. Cell Rep. Mar 28;18(13):3105-3116. doi: 10.1016/j.celrep.2017.03.017. PubMed PMID: 28355563.

 

Yang ASP, O’Neill, MT, Jennison C,  Lopaticki S, Allison CC, Armistead JS,   Erickson SN, Rogers KL, Ellisdon AM, Whisstock JC, Tweedell RE, Dinglasan RR, Douglas DN, Kneteman NM, BoddeyJA.  (201)Cell traversal activity facilitates plasmodium falciparum infection of human hepatocytes in vivo.   Cell Rep. 2017 Mar 28;18(13):3105-3116. doi: 10.1016/j.celrep.2017.03.017. PMID:     28355563

 

Yu, Q. Xiang, P.S. Manos, D.E. Soltis, P.S. Soltis, B.H. Song, S. Cheng, X. Liu, G.K. Wong. (2017) Whole-genome duplication and molecular evolution in Cornus L (Cornaceae) – Insights from transcriptome sequences. PLoS One 12: e0171361. PMID: 28225773. DOI: 10.1371/journal.pone.0171361

 

 

2016

 

Multiple PI

Ahmed M, Pal A, Houghton M, Barakat K (2016) A Comprehensive Computational Analysis for the Binding Modes of Hepatitis C Virus NS5A Inhibitors: The Question of Symmetry. ACS Infect Dis. Nov 11;2(11):872-881. Epub 2016 Aug 3. PMID: 27933783

 

Alipour, D. Zaidi, R. Valcheva, J. Jovel, I. Martínez, C. Sergi, J. Walter, A.L. Mason, G.K. Wong, L.A. Dieleman, et al (2016) Mucosal barrier depletion and loss of bacterial diversity are primary abnormalities in paediatric ulcerative colitis. J. Crohns Colitis 10: 462-471. PMID: 26660940. DOI: 10.1093/ecco-jcc/jjv223

 

Burton CE, Doucette K, Mabilangan CA, Plitt SS, Lee BE, Preiksaitis JK. (2016) Hepatitis B and C serologic profiles of Canadian organ donors and recipients: retrospective 10 year review at a single center. Transplant Infect Dis 2016, 18(4):520-8. doi: 10.1111/tid.12558

 

Doucette K, Preiksaitis J, Plitt S, Mabilangan C, Lee B, et al. (2016) Hepatitis B and C Serologic Profiles of Canadian Organ Donors and Recipients: Retrospective 10 Year Review at a Single Center. Transplant Infectious Disease. In Press 2016.

 

Galenza A, Hutchinson J, Campbell SD, Hazes B, Foley E. (2016). Glucose modulates Drosophila longevity and immunity independent of the microbiota. Biol Open 5(2):165-73. doi: 10.1242/bio.015016.

 

Gentile, J.A. Tuszynski and K.H. Barakat (2016) Modelling DNA Repair Pathways: Recent Advances and Future Directions, Current Pharmaceutical Design 22. Curr Pharm Des. 2016;22(23):3527-46. PMID: 27093954

 

Gentile, J.A. Tuszynski and K.H. Barakat (2016) New Design of Nucleotide Excision Repair (NER) Inhibitors for Combination Cancer Therapy, Journal of Molecular Graphics and Modelling. J Mol Graph Model. Apr;65:71-82. doi: 10.1016/j.jmgm.2016.02.010. Epub 2016 Feb 26. PMID: 26939044

 

K.L. Gilroy, A. Terry, A. Naseer, J. de Ridder, A. Allahyar, W. Wang, E. Carpenter, A. Mason, G.K. Wong, E.R. Cameron, et al. (2016) Gamma-retrovirus integration marks cell type-specific cancer genes: A novel profiling tool in cancer genomics. PLoS One 11: e0154070. PMID: 27097319. DOI: 10.1371/journal.pone.0154070

 

Hasing ME, Hazes B, Lee BE, Preiksaitis JK, Pang XL. (2016) A next generation sequencing-based method to study the intra-host genetic diversity of norovirus in patients with acute and chronic infection. BMC Genomics. Jul 1;17:480. doi: 10.1186/s12864-016-2831-y. PMID: 27363999

 

James, KT, Cooney, B., Agopsowicz K., Trevors, MA, Mohamed, A, Stoltz, D., Hitt, M., Shmulevitz M (2016) High-throughput Approach for Purification of Infectious Virions. Scientific Reports Nov 9;6:36826. doi: 10.1038/srep36826.

 

Jovel, J. Patterson, W. Wang, N. Hotte, S. O’Keefe, T. Mitchel, T. Perry, D. Kao, A. L. Mason, K. L. Madsen, G. Wong (2016) Characterization of the Gut Microbiome Using 16S or Shotgun Metagenomics. Frontiers in Microbiology 7:459 PMID: 27148170. DOI: 10.3389/fmicb.2016.00459

 

Landi A, Broadhurst D, Vernon SD, Tyrrell DLJ, Houghton M. (2016) Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome.  Cytokine Feb 78:27-36

 

Logan M, Law J, Wong J, Hockman D, Landi A, Chen C, Crawford K, Kundu J, Baldwin L, Johnson J, Dahiya A, Lachance G, Marcotrigiano J, Law M, Foung S, Tyrrell DLJ, Houghton M. (2016)  Native folding of a recombinant gpE1/gpE2 heterodimer vaccine antigen from a precursor protein fused with FcIgG.  J Virology.  October 19, Epub ahead of print  DOI:10.1128/JVI.01552-16

 

Neufeldt CJ, Joyce MA, VanBuren N, Kierkegaard K,  Levin A,  Gale Michael Jr., Tyrrell DLJ*, and Wozniak RW*. (2016) The hepatitis C virus-induced membranous web and associated nuclear transport machinery limit access of pattern recognition receptors to viral replication sites. PLoS Pathogens 10;12(2):e1005428. doi: 10.1371/journal.ppat.1005428. eCollection 2016. (*-co-senior authors)

 

O’Shea D, Law J, Egli A, Douglas D, Lund G, Forester S, Lambert J, Law M, Burton DR, Tyrrell DLJ, Houghton M, Humar A, Kneteman N. (2016)  Prevention of HCV infection using a broad cross-neutralizing monoclonal antibody (AR4A) and Epigallocatechin-Gallate.  Liver Transpl. 2016 March 22(3):324-32. doi: 10.1002/lt.24344. [Epub ahead of print]

 

Preiksaitis JK, Hayden RT, Tong Y, Pang XL, Fryer JF, Heath AB, Cook L, Petrich AK, Yu B Caliendo AM. (2016)  Are We there Yet? Impact of the First International Standard for Cytomegalovirus DNA on the Harmonization of Results Reported on Plasma Samples. Clin Infect Dis, 63(5):583-9. doi: 10.1093/cid/ciw370.

 

Galenza A, Hutchinson J, Campbell SD, Hazes B, Foley E. (2016) Glucose modulates Drosophila longevity and immunity independent of the microbiota. Biol Open. Jan 21;5(2):165-73. doi: 10.1242/bio.015016. PMID: 26794610

 

Qiu Y, Lee BE, Ruecker NJ, Neumann N, Ashbolt N, Pang X. (2016) A one-step centrifugal ultrafiltration method to concentrate enteric viruses from wastewater. J Virol Methods. Nov;237:150-153. doi: 10.1016/j.jviromet.2016.09.010. Epub 2016 Sep 11. PMID: 27630040

 

Syedbasha M, Linnik J, Santer D, O’Shea D, Barakat K, Joyce M, Khanna N, Tyrrell DL, Houghton M, Egli A (2016) An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions. JoVE (Journal of Visualized Experiments): e53575-e53575. PMID: 27023275; DOI: 10.3791/53575

 

Suresh S, Lee BE, Robinson JL, Akinwumi MS, Preiksaitis JK. (2016) A risk-stratified approach to cytomegalovirus prevention in pediatric solid organ transplant recipients. Pediatr Transplant. Nov;20(7):970-980. doi: 10.1111/petr.12786. Epub 2016 Aug 26. PMID: 27565955

 

Syedbasha M, Linnik J, Santer D, O’Shea D, Barakat K, Joyce M, Khanna N, Tyrrell DL, Houghton M, Egli A. (2016) An ELISA Based Binding and Competition Method to Rapidly Determine Ligand-receptor Interactions.  Journal of Visualized Experiments.  Mar 14 (109), e53575, doi:10.3791/53575

 

 

Individual Publications

 

Abou El-Magd RM, Vozza NF, Tuszynski JA, Wishart DS. (2016) Isolation of soluble scFv antibody fragments specific for small biomarker molecule, L-Carnitine, using phage display. J Immunol Methods. Jan;428:9-19. doi: 10.1016/j.jim.2015.11.006. Epub 2015 Dec 1. PMID: 26608419

 

B.Acharya, J. Alexandre, K. Bendtz, P. Benes, J. Bernabeu, M. Campbell, S. Cecchini,J. Chwastowski, Y. Cho, A. Chatterjee, M. de Montigny, D. Derendarz, A. De Roeck, J. R. Ellis, M. Fairbairn, D. Felea, M. Frank, D. Frekers, C. Garcia, G. Giacomelli, M. Giorgini, D. Hasegan, T. Hott, J. Jakubek, A. Katre, D-W Kim, M.G.L. King, K. Kinoshita, D. Lacarrere, S. C. Lee C. Leroy, A. Margiotta, N. Mauri, N. E. Mavromatos, P. Mermod, V. A. Mitsou, R. Orava, L. Pasqualini, L. Patrizii, G. E. Pavalas J. L. Pinfold, M. Platkevic V. Popa, M. Pozzato, S. Pospisil, A. Rajantie, Z. Sahoun, M. Sakellariadou, S. Sarkar, G. Semenoff, G. Sirri, K. Sliwa, R. Soluk, M. Spurio, R. Staszewski, J. Swain, M. Tenti, V. Togo, M. Trzebinski, J. A. Tuszynski, V. Vento, O. Vives, Z. Vykydal, T. Whyntie and A. Widom (2016) Search for magnetic monopoles with the MoEDAL prototype trapping detector in 8 TeV proton-proton collision at the LHC, Phys Rev Lett. 2017 Feb 10;118(6):061801. doi: 10.1103/PhysRevLett.118.061801. Epub 2017 Feb 10.

Alhhazmi A, Hurteau D, Tyrrell GJ. (2016) Correction for Alhhazmi et al., Epidemiology of Invasive Group B Streptococcal Disease in Alberta, Canada, from 2003 to 2013. J Clin Microbiol. Dec 28;55(1):342-343. doi: 10.1128/JCM.02052-16. PMID: 28031447

 

Alhhazmi A, Hurteau D, Tyrrell GJ. (2016) Epidemiology of Invasive Group B Streptococcal Disease in Alberta, Canada, from 2003 to 2013. J Clin Microbiol.  Jul;54(7):1774-81. doi: 10.1128/JCM.00355-16. Epub 2016 Apr 20. Erratum in: J Clin Microbiol. 2016 Dec 28;55(1):342-343. PMID: 27098960

 

Andres A, Livingstone S, Kin T, Campbell PM, Senior PA, Kneteman NM, Bigam D, Shapiro AM.  (2016) Islet-after-failed-pancreas and pancreas-after-failed islet transplantation: two complementary rescue strategies to control diabetes. Islets. Feb 19 7(6), e1126036

 

Andres A, Kin T, O’Gorman D, Livingstone S, Bigam D, Kneteman N, Senior P, Shapiro AMJ. (2016) Clinical Islet isolation and transplantation outcomes with deceased cardiac death donors are similar to neurological determination of death donors. Transpl Int. Jan;29(1):34-40. Epub 2015 Sep 3

 

Andres A, Montano Loza A, Greiner R, Uhlich M, Ping J, Hoehn B, Bigam D, Shapiro J, Kneteman NM.  (2016) A novel learning algorithm to predict individual survival time after liver transplantation for primary sclerosing cholangitis. Submitted JAMA.

 

Aur, A. Bandrowski and J.A. Tuszynski (2016) The Intelligence of Structured Matter: A Theory of Structural Evolution and Interaction of Matter. P.S. Satsangi, S.R. Hameroff and V. Sahni (eds.), Consciousness: Integrating Eastern and Western Perspectives, New Age Books (Publishers), New Delhi, India

 

Ayoub, A. Rabab, J. Xiao, C. Lewis, T. Tilli, K. Arakawa, Y. Nindita, G. Chan, L. Sun, M.J.N. Glover, M. Klobukowski, and J.A. Tuszynski (2016) Antitumor activity of lankacidin antibiotics is due to microtubule stabilization via a paclitaxel-like mechanism, J Medicinal Chemistry Oct 27;59(20):9532-9540. Epub 2016 Oct 18. PMID: 27718573

 

Banerji A, Ng K, Moraes TJ, Panzov V, Robinson J, Lee BE. (2016) Cost-effectiveness of palivizumab compared to no prophylaxis in term infants residing in the Canadian Arctic. CMAJ Open. 2016 Oct 18;4(4):E623-E633. doi: 10.9778/cmajo.20150052. eCollection 2016 Oct-Dec. PMID: 28443266

 

Backes S, Jäger C, Dembek CJ, Kosinska AD, Bauer T, Stephan AS, Dišlers A, Mutwiri G, Busch DH, Babiuk LA, Gasteiger G, Protzer U. (2016) Protein-prime/modified vaccinia virus Ankara vector-boost vaccination overcomes tolerance in high-antigenemic HBV-transgenic mice. Vaccine Jan 6. pii: S0264-410X(15)01871-X. doi: 10.1016/j.vaccine.2015.12.060. [Epub ahead of print]

 

Barker KR, Conroy AL, Hawkes M, Murphy H, Pandey P, Kain KC (2016) Biomarkers of hypoxia, endothelial and circulatory dysfunction among climbers in Nepal with AMS and HAPE: a prospective case-control study. J Travel Med. Mar 16;23(3).

 

Bauman ME, Hawkes M, Bruce A, Siddons S, Massicotte P (2016) Immunizations in Children Requiring Warfarin Therapy. J Pediatr Hematol Oncol. Nov;38(8):e329-e332

 

Beatty JA, Majumdar SR, Tyrrell GJ, Marrie TJ, Eurich DT. (2016) Prognostic factors associated with mortality and major in-hospital complications in patients with bacteremic pneumococcal pneumonia: Population-based study. Medicine (Baltimore). Nov;95(46):e5179. PMID: 27861340

 

Beatty JA, Majumdar SR, Tyrrell GJ, Marrie TJ, Eurich DT. (2016) Current Smoking and Reduced Mortality in Bacteremic Pneumococcal Pneumonia: A Population-Based Cohort Study. Chest. Sep;150(3):652-60. doi: 10.1016/j.chest.2016.04.020. Epub 2016 May 3. PMID: 27151328

 

Belga S and Doucette K (2016) Hepatitis C in Non-Hepatic Solid Organ Transplant Candidates and Recipients: A New Horizon. World Journal of Gastroenterology 22(4):1650-1663.

 

Berenger B, Doucette K, Smith S. (2016) Epidemiology and risk factors for nosocomial bloodstream infections in solid organ transplants over a 10-year period. Transplant Infectious Diseases. Transplant Infectious Diseases 2016;18:183-190.

 

Boadu, N.Y., Amuasi, J., Ansong, D., Einsiedel, E., Menon, D., Yanow, S.K. (2016) Challenges with implementing malaria rapid diagnostic tests at primary care facilities in a Ghanaian district: a qualitative study. Malaria Journal 15:126.

 

Bourque, S. Jeandroz, V. Grandperret, N. Lehotai, S. Aimé, D.E. Soltis, N.W. Miles, M. Melkonian, M.K. Deyholos, J.H. Leebens-Mack, G.K. Wong, et al. (2016) The evolution of HD2 proteins in green plants. Trends Plant Sci. 21: 1008-1016. PMID: 27789157. DOI: 10.1016/j.tplants.2016.10.001

 

Bral M, Gala Lopez B, Bigam D, Kneteman N, Malcolm A, Livingstone S, Andres A, Emamaullee J, Russell L, Coussios C, West L, Andrewes C, Friend P, Shapiro AMJ.  (2016) Preliminary Single Centre Canadian Experience of Human Normothermic Ex Vivo Liver Perfusion: Results of a Clinical Trial.  Am J Transplant. Sep 17. doi: 10.1111/ajt.14049. [Epub ahead of print]  PMID:  27639262

 

Burak KW, Meeberg GA, Myers RP, Fick GH, Swain MG, Bain VG, Kneteman NM, Hilsden RJ. (2016) Validation of the Model of End-stage Liver Disease (MELD) for liver transplant allocation in Alberta: implications for future directions in Canada. Can J Gastroenterol Hepatol, 2016:1329532. doi: 10.1155/2016/1329532. Epub 2016 Apr 3.

 

Cairo, L. V. and R.W. Wozniak. (2016). The nuclear transport factor Kap121 is required for stability of the Dam1 complex and mitotic kinetochore bi-orientation. Cell Rep. Mar 15;14(10):2440-50. doi: 10.1016/j.celrep.2016.02.041. Epub 2016 Mar 3. PMID: 26947076

 

Cairo, L. V. and R.W. Wozniak. (2016). The nuclear transport factor Kap121 is required for stability of the Dam1 complex and mitotic kinetochore bi-orientation. Cell Reports. Mar 15;14(10):2440-50.

 

Cervera C, Cofan F, Hernandez C, Soy D, Marcos MA, Sanclemente G, Bodro M, Moreno A, Diekmann F, Campistol JM, Oppenheimer F (2016) Effect of mammalian target of rapamycin inhibitors on cytomegalovirus infection in kidney transplant recipients receiving polyclonal antilymphocyte globulins: a propensity score-matching analysis. Transpl Int. Nov;29(11):1216-1225

 

Chan and J.A. Tuszynski (2016)  Automatic Prediction of Tumour Malignancy in Breast Cancer with Fractal Dimension. Royal Society Open Science, Dec 7;3(12):160558. doi: 10.1098/rsos.160558. eCollection 2016 Dec. PMID: 28083100

 

Chan, WF, J.A. Parks, B. G. Magor, and K. E. Magor (2016) The minor MHC Class I gene UDA is regulated by let-7 microRNA. Journal of Immunology, 197 (4): 1212-20.

 

Charchuk R, Makelele JPK, Kasereka MC, Houston S, Hawkes MT (2016) Burden of malaria is higher among children in an internal displacement camp compared to a neighbouring village in the Democratic Republic of the Congo. Malar J. Aug 25;15(1):431.

 

Chaurasiya, S.,* Hew, P.,* Crosley, P., Sharon, D., Potts, K., Agopsowicz, K., Long, M., Shi, C.-X., Hitt, M.M. (2016) Breast cancer gene therapy using an adenovirus encoding human IL-2 under control of mammoglobin promoter/enhancer sequences. Cancer Gene Therapy 23, 178-187.  *both authors contributed equally

 

Chen R, Kobewka M, Addison W, LaChance G, Tyrrell DLJ.  (2016)   Intrinsic Viral Factors are the Dominant Determinants of the Hepatitis C Virus Response to Interferon Alpha Treatment in Chimeric Mice.  PLoS One 11(1):30147007. http://dx.doi.org/10.1371/journal.pone.0147007

 

Cheung SM, Ostergaard HL. (2016) Pyk2 Controls Integrin-Dependent CTL Migration through Regulation of De-Adhesion. J Immunol. Sep 1;197(5):1945-56. doi: 10.4049/jimmunol.1501505. Epub 2016 Jul 25. PMID: 27456486

 

Cleary S, Doucette K, Doig C, Coffin C, Grant D, et al. (2016) Canadian Association of General Surgeons position statement: recommendations for surgeons with blood-borne communicable diseases. Can J Surg  59(1):7615.

 

Conroy AL, Hawkes M, Hayford K, Hermann L, McDonald CR, Sharma S, Namasopo S, Opoka RO, John CC, Liles WC, Miller C, Kain KC. (2016) Methemoglobin and nitric oxide therapy in Ugandan children hospitalized for febrile illness: results from a prospective cohort study and randomized double-blind placebo-controlled trial. BMC Pediatr. Nov 4; 16(1):177.

 

Conroy AL, Hawkes M, McDonald CR, Kim H, Higgins SJ, Barker KR, Namasopo S, Opoka RO, John CC, Liles WC, Kain KC (2016) Host Biomarkers Are Associated With Response to Therapy and Long-Term Mortality in Pediatric Severe Malaria. Open Forum Infect Dis. 2016 Jun 20;3(3):ofw134. eCollection 2016.

 

Conroy AL, Hawkes M, Elphinstone RE, Morgan C, Hermann L, Barker KR, Namasopo S, Opoka RO, John CC, Liles WC, Kain KC (2016) Acute Kidney Injury Is Common in Pediatric Severe Malaria and Is Associated With Increased Mortality. Open Forum Infect Dis. Feb 26;3(2):ofw046. doi: 10.1093/ofid/ofw046. eCollection 2016 Mar

 

T.J.A. Craddock, S.R. Hameroff and J.A. Tuszynski (2016) The Quantum Underground- Where Mind and Life Originate, 58 pages, in R. Poznanski, J.A. Tuszynski and T. Feinberg  (eds.), The Biophysics of Consciousness: A Foundational Approach, World Scientific

 

R. Darestani, P. Winter, E. N. Kitova, J. A. Tuszynski and J. S. Klassen (2016) Screening Anti-Cancer Drugs against Tubulin using Catch-and-Release Electrospray Ionization Mass Spectrometry. J Am Soc Mass Spectrom. May; 27(5):876-85. doi: 10.1007/s13361-016-1360-x. Epub 2016 Mar 4. PMID: 26944280

 

Dauber, B., Poon, D., Dos Santos, T., Duguay, B.A., Mehta, N., Saffran, H.A., and Smiley, J.R. (2016) The herpes simplex virus virion host shutoff protein enhances translation of viral true late mRNAs independently of suppressing protein kinase R and stress granule formation. J. Virol. 90: 6049-6057.

 

A. Deriu, G. Grasso, J. A. Tuszynski, D. Massai, D. Gallo, U. Morbiducci, and A. Danani (2016) Characterization of the AXH Domain of Ataxin-1 Using Enhanced Sampling and Functional Mode Analysis, PROTEINS: Structure, Function, and Bioinformatics. Proteins. May;84(5):666-73. doi: 10.1002/prot.25017. Epub 2016 Mar 9. PMID: 26879337

 

G.R. de Melo, M. de Montigny, J. Pinfold and J.A. Tuszynski (2016) Symmetries and soliton solutions of the Galilean complex Sine-Gordon equation, Physics Letters A (accepted January 28, 2016),

 

Deriu MA, Grasso G, Tuszynski JA, Massai D, Gallo D (2016) Morbiducci U, Danani A Characterization of the AXH domain of Ataxin-1 using enhanced sampling and functional mode analysis. Proteins. May;84(5):666-73. doi: 10.1002/prot.25017. Epub 2016 Mar 9. PMID: 26879337

 

Deriu MA, Grasso G, Tuszynski JA, Gallo D, Morbiducci U, Danani A. (2017) Josephin Domain Structural Conformations Explored by Metadynamics in Essential Coordinates. PLoS Comput Biol. Jan 8;12(1):e1004699. doi: 10.1371/journal.pcbi.1004699. eCollection 2016 Jan. PMID: 26745628

 

Dharnidharka VR, Webster AC, Martinez OM, Preiksaitis JK, Leblond V , Choquet S. (2016) Post-transplant lymphoproliferative disorders. Nat Rev Dis Primers 2016, 2:15088. doi: 10.1038/nrdp2015.88

 

Dong M, Artusa P, Kelly SA, Fournier M, Baldwin TA, Mandl JN, and Melichar HJ (2016) Alterations in the thymic selection threshold skew the self-reactivity of the T cell receptor repertoire in neonates. J Immunol. 2017 Aug 1;199(3):965-973. doi: 10.4049/jimmunol.1602137. Epub 2017 Jun 28. PMID: 28659353; **We contributed data using our HYcd4 mouse model to examine neonatal thymocyte selection and provided intellectual contributions (~10% contribution)

 

Doucette K, Weinkauf J, Kapasi A, Lien D, Halloran K. (2016) Outcomes of Lung Transplantation in Recipients with Hepatitis C Virus Infection. American Journal of Transplantation. Aug;16(8):2445-52. doi: 10.1111/ajt.13796. Epub 2016 Apr 19.

 

Doucette K, Sumner S, Weinkauf J (2016) Treatment of Hepatitis C in a lung transplant recipient with sofosbuvir and daclatasvir. Journal of Heart and Lung Transplantation. Feb 8, PMID: 26944671

 

Douglas DN, Pu CH, Lewis JT, Logan M, Lund G, Addison WR, Bhat R, Anwar-Mohamed A, Lehner R, Kneteman NM.  (2016) Oxidative stress attenuates lipid synthesis and increases mitochondrial fatty acid oxidation in hepatoma cells infected with hepatitis C virus. J Biol Chem. 2016 Jan 22; 291(4): 1974-90.  Epub 2015 Dec1

 

Elphinstone RE, Conroy AL, Hawkes M, Hermann L, Namasopo S, Warren HS, John CC, Liles WC, Kain KC (2016) Alterations in systemic extracellular heme and hemopexin are associated with adverse clinical outcomes in Ugandan children with severe malaria. J Infect Dis. Oct 15;214(8):1268-75

 

Fleming-Canepa, X., S.M. Jensen, C. M. Mesa, L. Diaz-Satizabal, A. J. Roth, J. A. Parks-Dely, D. A. Moon, J. P. Wong, D. Evseev, D. A. Gossen, D. G. Tetrault and K. E. Magor (2016) Extensive allelic diversity of MHC class I in wild mallard ducks. Journal of Immunology 197 (3):783-94.

 

Fortún J, Muriel A, Martín-Dávila P, Montejo M, Len O, Torre-Cisneros J, Carratalá J, Muñoz P, Fariñas C, Moreno A, Fresco G, Goikoetxea J, Gavaldá J, Pozo JC, Bodro M, Vena A, Casafont F, Cervera C, Silva JT, Aguado JM; Grupo de Estudio de Infección en Pacientes Trasplantados-Grupo de Estudio de Micología Médica (Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica), and Red Española de Investigación en Patología Infecciosa. (2016) Caspofungin versus fluconazole as prophylaxis of invasive fungal infection in high-risk liver transplantation recipients: A propensity score analysis. Liver Transpl. Apr;22(4):427-35

 

Freedman SB, Xie J, Neufeld MS, Hamilton WL, Hartling L, Tarr PI; Alberta Provincial Pediatric Enteric Infection Team (APPETITE), Preiksaitis JK. (2016) Shiga Toxin-Producing Escherichia coli Infection, Antibiotics, and Risk of Developing Hemolytic Uremic Syndrome: A Meta-analysis. Clin Infect Dis. Feb 24. pii: ciw099. [Epub ahead of print]

 

Freedman H, Logan MR, Law JL, Houghton M. (2016) Structure and Function of the Hepatitis C Virus Envelope Glycoproteins E1 and E2: Antiviral and Vaccine Targets. ACS Infect Dis. 2:749-762. Epub 2016 Aug 16

 

Ahmed M, Pal A, Houghton MBarakat K. (2016) A Comprehensive Computational Analysis for the Binding Modes of Hepatitis C Virus NS5A Inhibitors: The Question of Symmetry. ACS Infect Dis.  2:872-881.

 

Fryer JF, Heath AB, Minor PD; Collaborative Study Group, Preiksaitis JK. (2016) A collaborative study to establish the 1st WHO International Standard for human cytomegalovirus for nucleic acid amplification technology. Biologicals. 2016 May 11. pii: S1045-1056(16)30007-0. doi: 10.1016/j.biologicals.2016.04.005. [Epub ahead of print]

 

Ganesan A, Barakat K (2016) Target fishing: a key to unlock the One-To-Many puzzle in drug discovery. Journal of Pharmaceutical Care & Health Systems: 1-2.

 

Garant K, Shmulevitz M., Pan L, Daigle R, Ahn DG, Gujar S, Lee PW. (2016) Oncolytic reovirus induces intracellular redistribution of Ras to promote apoptosis and progeny virus release.  Oncogene May 11. doi: 10.1038/onc.2015.136.

 

Geissler E, Schnitzbauer AA, Zulke C, Lamby PE, Proneth A, Duvoux C, Burra P, Jauch, KW, Rentsch M, Ganten TM, Schmidt J, Settmacher U, Heise M, Rossi G, Cillo U, Kneteman N, Adam R, van Hoek B, Bachellier P, Wold P, Rostaing L, Bechstein WO, Rizell M, Powell J, Hidalgo E, Gugenheim J, Wolters H, Brockmann J, Roy A, Mutzbauer I, Schlitt A, Beckebaum S, Graeb C, Nadalin S, Valente U, Schanez Turrion V, Jamieson N, Scholz T, Colledan M, Fandrich F, Becker T, Soderdahl G, Chazouilleres, Makisola H, Pageaux GP, Steininger R, Soliman T, de Jong KP, Pirenne J, Margreiter R, Pratschke J, Pinna AD, Hauss J, Schreiber S, Strasser S, Klempnauer J, Troisi RL, Bhoori S, Lerut J, Bilbao I, Klein CG, Konigsrainer A, Mirza Daruis, Otto G, Mazzaferro V, Neuhaus P, Schlitt HJ. (2016) Sirolimus use in liver transplant recipients with hepatocellular carcinoma: A randomized, multi-centre, open-label phase 3 trial. Transplantation Jan;100(1):116-25

 

Gilroy, A. Terry, A. Naseer, J. Ridder, A. Allahyar, W. Wang, E. Carpenter, A. Mason, E. Cameron, A. Kilbey, J. Neil (2016) Gamma-retrovirus integration marks cell type-specific cancer genes: A novel profiling tool in cancer genomics. PLoS One 11: e0154070

 

P.E. Ghaly, R. A. El-Magd, C. Churchill, J.A. Tuszynski and F.G. West (2016) A New antiproliferative Noscapine Analogue: Chemical Synthesis and Biological Evaluation. Oncotarget. Jun 28;7(26):40518-40530. doi: 10.18632/oncotarget.9642. PMID: 27777381

 

S.T. Glantz, E.J. Carpenter, M. Melkonian, K.H. Gardner, E.S. Boyden, G.K. Wong, B.Y. Chow (2016) Functional and topological diversity of LOV domain photoreceptors. Proc. Natl. Acad. Sci. USA 113: E1442- E1451. PMID: 26929367. DOI: 10.1073/pnas.1509428113

 

Good, M.F., Yanow, S.K. (2016) Cryptic epitopes should not be forgotten in vaccine design. Expert Review of Vaccines. Mar 21:1-2.

 

Gopal K, Gupta N, Zhang H, Alshareef A, Alqahtani H, Bigras G, Lewis J, Douglas D, Kneteman N, Lavasanifar A, Lai R.  (2016) Oxidative stress induces the acquisition of cancer stem-like phenotype in breast cancer detectable by using a Sox2 regulatory region-2 (SRR2) reporter. Oncotarget  Jan 19;7(3):3111-27

 

Götte M and Feld, Jordan J (2016) Direct-acting antiviral agents for hepatitis C: structural and mechanistic insights.  Nat Rev Gastroenterol Hepatol. Jun;13(6):338-51. doi: 10.1038/nrgastro.2016.60. Epub 2016 May 5. Review.

 

Golec DP, Henao Caviedes LM and Baldwin TA  (2016) RasGRP1 and RasGRP3 Are Required for Efficient Generation of Early Thymic Progenitors. The Journal of Immunology. 197(5): 1743-53. 2016

 

Graham SM, Chen J, Chung DW, Barker KR, Conroy AL, Hawkes MT, Namasopo S, Kain KC, López JA, Liles WC (2016) Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial. Malar J. Feb 2;15(1):56.

 

Hamula CL, Peng H, Wang Z, Tyrrell GJ, Li XF, Le XC. (2016) An improved SELEX technique for selection of DNA aptamers binding to M-type 11 of Streptococcus pyogenes. Methods. Mar 15;97:51-7. doi: 10.1016/j.ymeth.2015.12.005. Epub 2015 Dec 8. PMID: 26678795

 

Hamula, C., H. Peng, Z. Wang, G.J. Tyrrell, X-F. Li and X.C. Le.  (2016) An improved SELEX technique for selection of DNA aptamers binding to M-type 11 of Streptococcus pyogenes. Methods. 2015 Dec 8. pii: S1046-2023(15)30173-0. doi: 10.1016/j.ymeth.2015.12.005. PMID:26678795.

 

Hamze H, Charchuk R, Makelele JPK, Kasereka MC, Mashukano L, Hawkes MT (2016) Lack of household clustering of malaria in a complex humanitarian emergency: implications for active case detection. Pathog Glob Health Aug 25:1-5.

 

Harrison, M.L., Desaulniers, M., Noyce, R.S., and Evans, D.H. (2016) The vaccinia virus I3 single-strand binding protein encodes an acidic C-terminal tail that regulates assembly of DNA-protein complexes. Virology 489:212-222.

 

Hawkes MT, Brophy JC, Mwinjiwa E, Mateyu G, Sodhi SK, Chan AK (2016) Survival Outcomes in a Pediatric Antiretroviral Treatment Cohort in Southern Malawi. PLOS ONE. Nov 3; doi.org/10.1371/journal.pone.0165772

 

Healey MA, Woodside MT, Tuszynski JA. (2016) Phase transitions and structure analysis in wild-type, A30P, E46K, and A53T mutants of α-synuclein. Eur Biophys J. May;45(4):355-64. doi: 10.1007/s00249-015-1103-0. Epub 2015 Dec 22. PMID: 26695014

 

Higgins SJ, Purcell LA, Silver KL, Tran V, Crowley V, Hawkes M, Conroy AL, Opoka RO, Hay JG, Quaggin SE, Thurston G, Liles WC, Kain KC (2016) Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria. Sci Transl Med. Sep 28;8(358):358ra1

 

Huang W, Wang Y, Chen C, Law JL, Houghton M, Chen L. (2016) Fabrication of flexible self-standing all-cellulose nanofibrous composite membranes for virus removal. Carbohydrate Polymers. 143:9-17. doi: 10.1016/j.carbpol.2016.02.011.

 

A.Huczynski, U. Majcher,  E. Maj, J.  Wietrzyk, J. Janczak, M.  Moshari, J.A. Tuszynski and F. Bartl (2016) Synthesis, antiproliferative activity and molecular docking of Colchicine derivatives. Bioorg Chem. 2016 Feb;64:103-12. doi: 10.1016/j.bioorg.2016.01.002. Epub 2016 Jan 12. PMID: 26794327

 

Hull M, Shafran S, Wong A, Tseng A, Giguère P, Barrett L, Haider S, Conway B, Klein M, Cooper C. (2016) Updated Canadian HIV/hepatitis C adult guidelines for management and treatment. J Assoc Med Microbiol Infect Dis Can 2016; Volume 2016, Article ID 4385643. http://dx.doi.org/10.1155/2016/4385643.

 

Jeandroz, D. Wipf, D.J. Stuehr, L. Lamattina, M. Melkonian, Z. Tian, Y. Zhu, E.J. Carpenter, G.K. Wong, D. Wendehenne (2016) Occurrence, structure, and evolution of nitric oxide synthase-like proteins in the plant kingdom. Sci. Signal. 9: re2. PMID: 26933064. DOI: 10.1126/scisignal.aad4403

 

Jacobson I, Zeuzem S, Flisiak R, Knysz B, Lueth S, Zarebska-Michaluk D, Janczewska E, Ferenci P, Diago M, Zignego AL, Safadi R, Baruch Y, Abdurakhmanov D, Shafran S, Thabut D, Bruck R, Gadano A, Thompson AJ, Kopit J, McPhee F, Michener T, Hughes E, Yin PD, Noviello S. (2016) Daclatasvir versus telaprevir plus peginterferon alfa/ribavirin for HCV genotype 1. World J Hepatol 2016; 22:3418-31.
Lionel D. Jensen and David J. Marchant. (2016) Emerging pharmacologic targets and treatments for myocarditis. Pharmacology and Therapeutics Mar 20. pii: S0163-7258(16)30014-6 Review.

 

Jia, G. Li, T.G. Köllner, J. Fu, X. Chen, W. Xiong, B.J. Crandall-Stotler, J.L. Bowman, D.J. Weston, Y. Zhang, G.K. Wong et al. (2016) Microbial-type terpene synthase genes occur widely in nonseed land plants, but not in seed plants. Proc. Natl. Acad. Sci. USA 113: 12328-12333. PMID: 27791023. DOI: 10.1073/pnas.1607973113

 

Keck, ZY, Wang Y, Lau P, Lund G, Rangarajan S, Fauvelle C,Liao GC, Holtsberg FW, Warfield KL, Aman MJ, Pierce BG, Fuest T, Bailey JR, Baumert TF, Mariuzza RA, Kneteman NM, Foung SKH.  (2016) Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.  Hepatology Sep 19. doi: 10.1002/hep.28850. [Epub ahead of print]  PMID: 27641232

 

Koehli S, Golec DP and Baldwin TA.  (2016) TCR Affinity and Signaling during Thymocyte Selection.  Encyclopedia of Immunobiology. Elsevier Publishing Group. In press

 

Kuban-Jankowska, K. K. Sahu, M. Gorska, P. Niedzialkowski, J. A. Tuszynski, T. Ossowski, and M. Wozniak (2016) Aurintricarboxylic acid structure modifications lead to reduction of inhibitory properties against virulence factor YopH and higher cytotoxicity. World J Microbiol Biotechnol. Oct;32(10):163. doi: 10.1007/s11274-016-2123-3. Epub 2016 Aug 25. PMID: 27562597

 

Kuban-Jankowska A, Sahu KK, Gorska M, Tuszynski JA, Wozniak M. (2016) Chicoric acid binds to two sites and decreases the activity of the YopH bacterial virulence factor. Oncotarget. Jan 19;7(3):2229-38. doi: 10.18632/oncotarget.6812. PMID: 26735581

 

Kulkarni AS, Damha MJ, Schinazi RF, Mo H, Doehle B, Sagan SM, and Götte M (2016) A complex network of interactions between S282 and G283 of HCV NS5B and the template strand affect susceptibility to Sofosbuvir and Ribavirin Antimicrob. Antimicrob Agents Chemother.  Mar 25;60(4):2018-27. doi: 10.1128/AAC.02436-15. Print 2016 Apr.

 

Kumar, K. Boone, J.A. Tuszynski, P. Barclay and C. Simon (2016) Possible existence of optical communication channels in the brain, Scientific Reports Nov 7;6:36508. doi: 10.1038/srep36508. PMID: 27819310

 

Anil Kumar *Shangmei Hou Adriana M. Airo Daniel Limonta Valeria Mancinelli William Branton Christopher Power Tom C. Hobman *authors contributed equally. (2016). Zikavirus inhibits type-I interferon production and downstream signaling. EMBO Reports. 17(12): 1766-1775.

 

T.S. Lane, C.S. Rempe, J. Davitt, M.E. Staton, Y. Peng, D.E. Soltis, M. Melkonian, M. Deyholos, J.H. Leebens-Mack, M. Chase, G.K. Wong et al (2016) Diversity of ABC transporter genes across the plant kingdom and their potential utility in biotechnology. BMC Biotechnol. 16: 47. PMID: 27245738. DOI: 10.1186/s12896-016-0277-6

 

Leal L, León A, Torres B, Inciarte A, Lucero C, Mallolas J, Laguno M, Martínez-Rebollar M, González-Cordón A, Manzardo C, Rojas J, Pich J, Arnaiz JA, Gatell JM, García F; RALPEP Study Group (Cervera C). (2016) A randomized clinical trial comparing ritonavir-boosted lopinavir versus raltegravir each with tenofovir plus emtricitabine for post-exposure prophylaxis for HIV infection. J Antimicrob Chemother Jul;71(7):1987-93

 

Lee E, Alsagheir A, Wu X, Hammack C, McLauchlan J, Watanabe N, Wakita T, Kneteman N, Douglas D, Tang H. (2016) Hepatitis C virus induced degradation of cell death-inducing DFFA-like effector B leads to hepatic lipid dysregulation. J Virol. 2016 Mar 29;90 (8) 4174-85

 

Leis JA, Evans GA, Ciccotelli W, Garber G, Gregson D, Lee TC, Le Saux N, McFadden DR, Saxinger L, Shafran S, Gold WL. (2016) Choosing Wisely Canada- top five list in infectious diseases: an official position statement of the Association of Medical Microbiology and Infectious Diseases Canada. J Assoc Med Microbiol Infect Dis Can 1:8-12.

 

Liu CH, Lin CC, Hsu WC, Chung CY, Lin CC, Jassey A, Chang SP, Tai CJ, Tai CJ, Shields J, Richardson CD, Yen MH, Tyrrell DLJ, Lin LT.  (2016)Highly Bioavailable Silibinin Nanoparticles Inhibit Hepatitis C Virus Infection.    Gut Jul 19. pii: gutjnl-2016-312019. doi: 10.1136/gutjnl-2016-312019

 

Livingstone S, Andres A, Shapiro J, Bigam D,  Kneteman NM (2016)  Diaphragmatic Hernia Following Living Donor Right Hepatectomy: Proposal for a screening protocol. Transplant Direct. Jun 2;2(7):e84.

 

López-Medrano F, Silva JT, Fernández-Ruiz M, Carver PL, van Delden C, Merino E, Pérez-Saez MJ, Montero M, Coussement J, de Abreu Mazzolin M, Cervera C, Santos L, Sabé N, Scemla A, Cordero E, Cruzado-Vega L, Martín-Moreno PL, Len Ó, Rudas E, de León AP, Arriola M, Lauzurica R, David M, González-Rico C, Henríquez-Palop F,  Fortún J, Nucci M, Manuel O, Paño-Pardo JR, Montejo M, Muñoz P, Sánchez-Sobrino B, Mazuecos A, Pascual J, Horcajada JP, Lecompte T, Lumbreras C, Moreno A, Carratalà J, Blanes M, Hernández D, Hernández-Méndez EA, Fariñas MC, Perelló-Carrascosa M, Morales JM, Andrés A, Aguado JM; Spanish Network for Research in Infectious Diseases (REIPI), the Group for the Study of Infection in Transplant Recipients (GESITRA) of the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC), the Study Group for Infections in Compromised Hosts (ESGICH) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), and the Swiss Transplant Cohort Study (STCS) (2016) Risk Factors Associated With Early Invasive Pulmonary Aspergillosis in Kidney Transplant Recipients: Results From a Multinational Matched Case-Control Study. Am J Transplant. Jul;16(7):2148-57

 

López-Medrano F, Fernández-Ruiz M, Silva JT, Carver PL, van Delden C, Merino E, Pérez-Saez MJ, Montero M, Coussement J, de Abreu Mazzolin M, Cervera C, Santos L, Sabé N, Scemla A, Cordero E, Cruzado-Vega L, Martín-Moreno PL, Len Ó, Rudas E, de León AP, Arriola M, Lauzurica R, David M, González-Rico C, Henríquez-Palop F,  Fortún J, Nucci M, Manuel O, Paño-Pardo JR, Montejo M, Muñoz P, Sánchez-Sobrino B, Mazuecos A, Pascual J, Horcajada JP, Lecompte T, Moreno A, Carratalà J, Blanes M, Hernández D, Fariñas MC, Andrés A, Aguado JM; Spanish Network for Research in Infectious Diseases (REIPI), the Group for the Study of Infection in Transplant Recipients (GESITRA) of the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC), the Study Group for Infections in Compromised Hosts (ESGICH) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), and the Swiss Transplant Cohort Study (STCS) (2016) Clinical Presentation and Determinants of Mortality of Invasive Pulmonary Aspergillosis in Kidney Transplant Recipients: A Multinational Cohort Study. Am J Transplant. Nov;16(11):3220-3234.

 

E Lytvyak, A Montano-Loza, A Mason (2016) Combination anti-retroviral therapy for patients with primary biliary cirrhosis World. J Gastroenterology 22(1): 349-360

 

Minu Maninder, D. Singh, T. Mahaddalkar, M.  Lopus, P. Winter; A. T Ayoub; K. Missiaen, T.  M. Tilli, M.  Pasdar and J.A.  Tuszynski (2016) Chemical synthesis, pharmacological evaluation and in silico analysis of new 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives as potential anti-mitotic agents, Bioorganic & Medicinal Chemistry Letters, volume 26, issue 15, pp. 3866-3861

 

Marrie TJ, Tyrrell GJ, Majumdar SR, Eurich DT. (2016) Asplenic patients and invasive pneumococcal disease-how bad is it these days? Int J Infect Dis. Oct;51:27-30. doi: 10.1016/j.ijid.2016.08.022. Epub 2016 Aug 30. PMID: 27590561

 

Maugarny-Calès, B. Gonçalves, S. Jouannic, M. Melkonian, G.K. Wong, P. Laufs. (2016) Apparition of the NAC transcription factors predates the emergence of land plants. Mol. Plant 9: 1345-1348. PMID: 27302340. DOI: 10.1016/j.molp.2016.05.016

 

Miller, R.R., M.G. Langille, V. Montoya, A. Crisan, A. Stefanovic, I. Martin, L. Hoang, D.M. Patrick, M. Romney, G.J. Tyrrell, S.J. Jones, F.S. Brinkman and P. Tang. (2016) Genomic analysis of a serotype 5 Streptococcus pneumoniae outbreak in British Columbia, Canada 2005-2009. Can J Infect Dis Med Microbiol. 2016;2016:5381871. doi: 10.1155/2016/5381871. Epub 2016 Apr 14. PMID: 27366170

 

El Moghazy W, Kashkoush S, Meeberg GA,  Kneteman NM.  (2016) Incidence, Characteristics, and Prognosis of Incidentally-discovered Hepatocellular Carcinoma after Liver Transplantation.   J Transplant  March;2016:1916387. doi: 10.1155/2016/1916387. Epub 2016 Jun 15.

 

Morcos, C. and D.N. Burshtyn, (2016) The Expanding Spectrum of Ligands for Leukocyte Immunoglobulin-Like Receptors (Brief Review)  J Immunol. Feb 1;196(3):947-55. doi: 10.4049/jimmunol.1501937.

 

Ngure M, Issur M, Shkriabai N, Liu HW, Cosa G, Kvaratskhelia M, Götte M (2016) Interactions of the Disordered Domain II of Hepatitis C Virus NS5A with Cyclophilin A, NS5B, and Viral RNA Show Extensive Overlap.  ACS Infect Dis. Nov 11;2(11):839-851.

 

Pabbaraju K, S Wong K Gill, K Fonseca, GA Tipples and R Tellier (2016) Simultaneous detection of Zika, Chikungunya and Dengue viruses by a multiplex real-time RT-PCR assay. J Clin Virol 83:66-7 (2016).

 

Pabbaraju K, S Wong, SJ Drews, G Tipples and R Tellier (2016) Full genome analysis of enterovirus D-68 strains circulating in Alberta, Canada. J Med Virol 88:1194-203 (2016).

 

Park LP, Chu VH, Peterson G, Skoutelis A, Lejko-Zupa T, Bouza E, Tattevin P, Habib G, Tan R, Gonzalez J, Altclas J, Edathodu J, Fortes CQ, Siciliano RF, Pachirat O, Kanj S, Wang A; International Collaboration on Endocarditis (ICE) Investigators (Cervera C) (2016) Validated Risk Score for Predicting 6-Month Mortality in Infective Endocarditis. J Am Heart Assoc. Apr 18;5(4):e003016

 

Parsons B, Foley E. (2016) Cellular immune defenses of Drosophila melanogaster. Dev Comp Immunol. May; 58:95-101. doi: 10.1016/j.dci.2015.12.019. Epub 2015 Dec 31. Review. PMID: 26748247

 

Parvez, L. B. Qhanya, N. T. Mthakathi, I. K. R. Kgosiemang, H. D. Bamal, N. S. Pagadala, T. Xie, H. Yang, H. Chen, C. W. Theron, R. Monyaki, S. C. Raselemane, V. Salewe, B. L. Mongale, R. G. Matowane, S. M. H. Abdalla, W. I. Booi, M. van Wyk, D. Olivier, C. E. Boucher, J. A. Tuszynski, J. M. Blackburn, J-H Yu, S. S. Mashele, W. Chen, K. Syed (2016) Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s Sci Rep. Sep 12;6:33099. doi: 10.1038/srep33099. PMID: 27616185

 

Paszkowski, P., Noyce, R.S., and Evans, D.H. (2016) Live-cell imaging of vaccinia virus genetic recombination. PLoS Pathogens. 12(8):e1005824. doi: 10.1371/journal.ppat.1005824

 

Perin, PM , Haid, S, Richard J. P. Brown, Doerrbecker, J, Schulze, K, Zeilinger, C, von Schaewen, M, Heller, B, Vercauteren, K, Luxenburger, E, Baktash, YM, Vondran, FWR, Speerstra, S, Awadh, A, Mukhtarov, F, Schang, LM, Kirschning, A, Müller, R, Guzman, CA, Kaderali, L, Randall, G, Meuleman, P, Ploss, A, Pietschmann, T. (2016) Flunarizine Prevents Hepatitis C Virus Membrane Fusion in a Genotype-dependent Manner by Targeting the Potential Fusion Peptide within E1. Hepatology 63(1):49-62.

 

Petkau, K., Fast, D., Duggal, A., and Foley E. (2016) Comparative evaluation of the genomes of common bacterial members of the Drosophila intestinal community. BioRxiv doi: http://dx.doi.org/10.1101/036020. Under review at Biology Direct. Research funded by CIHR.

 

Petkau K, Fast D, Duggal A, Foley E. (2016) Comparative evaluation of the genomes of three common Drosophila-associated bacteria. Biol Open. Sep 15;5(9):1305-16. doi: 10.1242/bio.017673. PMID: 27493201

 

Plitt SS, Osman M, Sahni V, Lee BE, Charlton C, Simmonds K. (2016) Examination of a prenatal syphilis screening program, Alberta, Canada: 2010-2011. Can J Public Health. Oct 20;107(3):e285-e290. doi: 10.17269/cjph.107.5320.

 

Preiksaitis JK, Cockfield SM, Peters A. Ljungman P, Syndman D, Boeckh M (eds). (2016) Epstein-Barr Virus Infection and Lymphoproliferative Disorders after Transplantation. Transplant Infections  (4th edition). Berlin Heidelberg Springer International Publishing 26;477-512

 

R. Poznanski, J.A. Tuszynski and T.E. Feinberg (eds.) (2016) Biophysics of Consciousness: A Foundational Approach, ISBN 9789814644259, World Scientific, Singapore

 

Ptak, C. and R. W. Wozniak. (2016). Nucleoporins and chromatin metabolism. Curr Opin Cell Biol. 40:153-160.

 

Rezania V, Coombe D, Tuszynski JA. (2016) A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models. Theor Biol Med Model. Mar 3;13:9. doi: 10.1186/s12976-016-0034-5. PMID: 26939615

 

Rietman and J.A. Tuszynski (2016) Thermodynamics and Cancer Dormancy: A Perspective. Thermodynamics and the Proliferation-Quiescence Dilemma, Springer Verlag, New York edited by Drs. X. Wang and F.Crea

 

Salari, I. Bókkon, F. Ghobadi, F. Scholkmann and J. A. Tuszynski (2016) Relationship between intelligence and spectral characteristics of brain biophoton emission: correlation does not automatically imply causation. Proc Natl Acad Sci U S A. Sep 20;113(38):E5540-1. doi: 10.1073/pnas.1612646113. Epub 2016 Sep 12. PMID: 27621479

 

Salari, F. Scholkmann, I. Bokkon, F. Shabhazi and J.A. Tuszynski (2016) Physical Mechanism for Retinal Discrete Dark Noise: Thermal Activation or Cellular Ultra-weak Photon Emission? PLoS One. Mar 7;11(3):e0148336. doi: 10.1371/journal.pone.0148336. eCollection 2016. PMID: 26950936

 

Sapisochin G, Facciuto M, Marti J, Mehta N, Yao FY, Vibert E, Cherqui D, Hernandez-Alejandro R,   Cucchetti A, Pinna S, Hwang S, Lee S, Agopian VG, Busuttil RW, Gores G, Rizvi S, Montenovo M, Reyes J, Cesaretti M, Soubrane 0, Reichman T, Seal J, Kim P, Klintmalm G, Sposito C, Mazzaferro V, Dutkowski P, Clavien PA, Toso C, Majno P, Kneteman N, Bruix J. (2016) iCCAInternational Consortium. Liver Transplantation for “Very Early” Intrahepatic Cholangiocarcinoma.  International retrospective study supporting a prospective assessment.  Hepatology Oct; 64(4):1178-88. [Epub 2016 Aug 24. PMID27481548]

 

Shafran SD. (2016) Live attenuated herpes zoster vaccine for HIV-infected adults. HIV Medicine; 17:305-10.

 

Shegarfi, H, Nestvold, J, Kane, K and Rolstad, B. (2016). Listeria monocytogenes infection differentially affects NK cell response and NK cell ligand expression, – depending on the infected cell type.Journal of Leukocyte Biology. 1: 1-2.

 

Shegarfi, H, Nestvold, J, Kane, K, and Rolstad, B. (2016). The rat non-classical MHC-I molecule RT1- CE16d is a ligand for the paired rat Ly49i4 and Ly49s4 NK cell receptors and Listeria monocytogenes infection influences its expression and recognition.Journal of Immunology. 1: 1-2

 

Shen Y, Cheng F, Sharma M, Merkulova Y, Raithatha SA, Parkinson LG, Zhao H, Westendorf K, Bohunek L, Bozin T, Hsu I, Ang LS, Williams SJ, Bleackley RC, Eriksson JE, Seidman MA, McManus BM, Granville DJ.  Granzyme B (2016) Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis.  Am J Pathol. Jan;186(1):87-100.

 

Stata, T.L. Sage, N. Hoffmann, S. Covshoff, G.K. Wong, R.F. Sage (2016) Mesophyll chloroplast investment in C3, C4 and C2 species of the genus Flaveria. Plant Cell Physiol. 57: 904-918. PMID: 26985020. DOI: 10.1093/pcp/pcw015

 

Stamatikos AD, da Silva RP, Lewis JT, Douglas DN, Kneteman NM, Jacobs RL, Paton CM. (2016) Tissue specific effects of dietary carbohydrates and obesity on ChREBPα and ChREBPβ expression. Lipids  Jan;51(1):95-104. Epub 2015 Nov 2

 

S.R. Stevenson, Y. Kamisugi, C.H. Trinh, J. Schmutz, J.W. Jenkins, J. Grimwood, W. Muchero, G.A. Tuskan, S.A. Rensing, D. Lang, G.K. Wong et al. (2016) Genetic analysis of Physcomitrella patens identifies ABSCISIC ACID NON-RESPONSIVE, a regulator of ABA responses unique to basal land plants and required for desiccation tolerance. Plant Cell 28: 1310-1327. PMID: 27194706. DOI: 10.1105/tpc.16.00091

 

Strunk, U., Ramos, D.G., Saffran, H.A., and Smiley J.R. (2016) Role of herpes simplex virus 1 VP11/12 tyrosine-based binding motifs for Src family kinases, p85, Grb2 and Shc in activation of the phosphoinositide 3-kinase-Akt pathway. Virology 498: 31-35

 

Suresh S, Tyrrell G, Alhhazami A, Escoredo S, Hawkes M (2016) Recurrent sepsis and neuroinvasive disease in a neonate culture positive for a group B Streptococcus CPS III serotype, hvgA+ strain. JMM Case Rep. Jun 25; 3(3):e005034

 

T.M. Tilli, C. da Silva Castro, J.A. Tuszynski, N. Carels (2016) A strategy to identify housekeeping genes suitable for analysis in breast cancer diseases. BMC Genomics. Aug 15;17(1):639. doi: 10.1186/s12864-016-2946-1. PMID:     27526934

 

T.M. Tilli, N. Carels, M. Pasdar and J.A. Tuszynski (2016) Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of a network of targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development, Oncotarget Sep 27;7(39):63189-63203. doi: 10.18632/oncotarget.11055. PMID: 27527857

 

Toso C, Axel A, Kneteman NM, Hernandez-Alejandro R, Majno P.  (2016) AFP:  further evidence to add a biological marker to refine Milan criteria.  Liver International, November  Volume 36, Issue 11, Pages 1580–1581. PMID: 27744652

 

Tsang, R.S.W., A. Li, A. Muller, M. Baikie, K. Whyte, M. Shuel, G.J. Tyrrell, J.A.L. Rotondo, S. Desai and J. Spika. (2016) Characterization of invasive Haemophilus influenzae isolated from Nunavut, Canada, 2000-2012. International Journal of Circumpolar Health. 75:29798, http://dx.doi.org/10.3402/ijch.v75.29798.

 

Turnbull H, Conroy A, Opoka RO, Namasopo S, Kain KC, Hawkes M (2016) Solar-powered oxygen delivery: proof of concept. Int J Tuberc Lung Dis. May;20(5):696-703.

 

J.A. Tuszynski, C. Wenger, D.E. Friesen and J. Preto (2016)  An Overview of sub-cellular mechanisms involved in the action of TTFields. Int J Environ Res Public Health. Nov 12;13(11). pii: E1128. PMID: 27845746

 

J.A. Tuszynski, T.M. Tilli and M.Levin (2016) Ion channel and neurotransmitter modulators as electroceutical approach to the control of cancer, Current Pharmaceutical Design, vol. 23, issue 46; DOI: 10.2174/1381612823666170530105837

 

J.A. Tuszynski (2016) Perspective on Non-genic Inheritance of Cellular Handedness, in: Ahead of the Curve: hidden breakthroughs in the biosciences, M. Levin and D. Adams (eds), IOP Publishing, Bristol, UK, 2016.

 

Carels N, Spinassé LB, Tilli TM, Tuszynski JA. (2016) Toward precision medicine of breast cancer. Theor Biol Med Model. Feb 29;13:7. doi: 10.1186/s12976-016-0035-4. Review. PMID: 26925829

 

Wang, H. Zhang, X. Wang, J. Patterson, P. Winter, K. Graham, S. Ghosh, J. C. Lee, C. D. Katsetos, J. Mackey, J. A. Tuszynski, G. K-S Wong, R. F. Ludueña (2016) Novel Mutations Involving βI-, βIIA-, or βIVB-Tubulin Isotypes with Functional Resemblance to βIII-Tubulin in Breast Cancer, Protoplasma 2017 May;254(3):1163-1173. doi: 10.1007/s00709-016-1060-1. Epub 2016 Dec 9. PMID: 27943021

 

White, D. Coombe, V. Rezania and J.A. Tuszynski (2016) Building a 3D Virtual Liver: Methods for Simulating Blood Flow and Hepatic Clearance on 3D Structures, PLoS One (accepted August 19, 2016)

 

Williams KJ, Eaton HE, Jones L, Rengan S, Burshtyn DN (2016) Vaccinia virus Western Reserve induces rapid surface expression of a host molecule detected by the antibody 4C7 that is distinct from CLEC2D. Microbiol Immunol. 2016 60:754-769.

 

Wu C, Zhang HF, Gupta N, Alshareef A, Wang Q, Huang YH, Lewis JT, Douglas DN, Kneteman NM, Lai, R.  A positive feeback loop involving the Wnt/β-catenin/MYC/Sox2 axix defines a high tumorigenic cell population in ALK-positive anaplastic large cell lymphoma.  J Hematol Oncol. 2016 Nov 8;9(1):120. PMID: 27821172

 

Vasco, T.L. Smalls, S.W. Graham, E.D. Cooper, G.K. Wong, D.W. Stevenson, R.C. Moran, B.A. Ambrose (2016) Challenging the paradigms of leaf evolution: Class III HD-Zips in ferns and lycophytes. New Phytol. 212: 745-758. PMID: 27385116. DOI: 10.1111/nph.14075

 

Xiao-Yang J, Steenbergen R, Tyrrell DLJ.  (2016) The use of human umbilical cord blood serum is beneficial for the continuous production of hepatitis C virus.  J Gen Virol.  Dec;97(12):3248-3252. doi: 10.1099/jgv.0.000636. Epub 2016 Oct 24.

 

Yanow, S.K., Gavina, K., Gnidehou, S., and Maestre, A. (2016) Impact of malaria in pregnancy as Latin America approaches elimination. Trends in Parasitology 32:416-27.

 

Yanow, S.K. (2016) Molecular diagnosis of malaria in low-resource settings. Point of Care 15:41-42.

 

Yeh LC, Banerjee A, Prasad V, Tuszynski JA, Weis AL, Bakos T, Yeh IT, Ludueña RF, Lee JC. (2016) Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells overexpressing the βIII isotype of tubulin. Invest New Drugs. Feb;34(1):129-37. doi: 10.1007/s10637-015-0315-6. Epub 2015 Dec 21. PMID: 26686345

 

Yerramsetty, M. Stata, R. Siford, T.L. Sage, R.F. Sage, G.K. Wong, V.A. Albert, J.O. Berry (2016) Evolution of RLSB, a nuclear-encoded S1 domain RNA binding protein associated with post-transcriptional regulation of plastid-encoded rbcL mRNA in vascular plants. BMC Evol. Biol. 16: 141. PMID: 27356975. DOI:10.1186/s12862-016-0713-1

 

 

 

 

2015

 

Acosta, N., Pukatzki, S., Raivio, S. (2015) The Vibrio cholerae Cpx envelope stress response senses and mediates adaptation to low iron. Journal of Bacteriology 2015 Jan;197(2):262-76. doi: 10.1128/JB.01957-14. Epub 2014 Nov 3.

Acosta, N., Pukatzki, S., Raivio, S.: (2015) The Cpx system regulates virulence gene expression in Vibrio cholerae. Infection & Immunity 83(6): 2396-408. 2015.

 

Ahmed M, Wang F, Levin A, Le C, Eltayebi Y, Houghton M, Tyrrell L, Barakat K. (2015) Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA. Drug Discov Today. May;20(5):548-61. doi: 10.1016/j.drudis.2015.01.008. Epub 2015 Jan 24.

 

Ahmed M, Wang F, Levin A, Le C, Eltayebi Y, Barakat K et al. (2015) Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA. Drug Discov Today.

 

Ahmed M, Barakat K (2015) Baby Steps Toward Modelling The Full human Programmed Death-1 (PD-1) Pathway. Receptors & Clinical Investigation 2(3), 124.

 

Ahmed M, Wang F, Levin A, Le C, Eltayebi Y, Houghton M, Tyrrell DLJ, Barakat K.  (2015) Targeting the “Achilles heel” of the hepatitis B virus:  A review of current treatments against covalently closed circular DNA (cccDNA).  Drug Discovery Today.  May;20(5):548-61. doi: 10.1016/j.drudis.2015.01.008. Epub 2015 Jan 24. Review.

Al-Adra DP, Gill RS, Axford SJ, Shi X, Kneteman N, Liau SS. (2015) Treatment of unresectable intrahepatic cholangiocarcinoma with yttrium-90 radioembolization: A systematic review and pooled analysis. EJSO 41 120-127.

 

Andres A, Kin T, O’Gorman D, Livingstone S, Bigam D, Kneteman N, Senior P, Shapiro AMJ. (2015) Clinical Islet isolation and transplantation outcomes with deceased cardiac death donors are similar to neurological determination of death donors. Transpl Int. Aug 15 doi: 10.1111/tri.12650 [Epub ahead of print]

 

Anggakusuma, Romero-Brey, I, Berger, C, Wieland, S, Colpitts, CC, Todt, D, Monteiro, P, Perin, P, Behrendt, P, Vondran, FWR, Xu, S, Goffinet, C, Schang, LM, Heim, MH, Bartenschlager, R, Pietschmann, T, Steinmann, E (2015) “Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus via blockage of membranous web formation”. Hepatology, 62(3):702-714.

 

M.M. Augustin, D.R. Ruzicka, A.K. Shukla, J.M. Augustin, C.M. Starks, M. O’Neil-Johnson, M.R. McKain, B.S. Evans, M.D. Barrett, A. Smithson, Wong GK, Deyholos MK, Edger PP, Pires JC, Leebens-Mack JH, Mann DA, Kutchan TM.

(2015) Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 82: 991-1003. PMID: 25939370. DOI: 10.1111/tpj.12871

 

A.T. Ayoub, M. Klobukowski and J.A. Tuszynski (2015) The Driving Force for Microtubule Disassembly is

Explained by a Detailed Balance of its Interaction Energy Per Residue, PLoS Computational

Biology June 1, DOI: 10.1371/journal.pcbi.1004313, IF=5.759.

 

Bachmann, V., Kostiuk, B., Unterweger, D., Pukatzki, S.: (2015) Bile salts modulate the mucin-activated type VI secretion system of pandemic Vibrio cholerae. PLoS Neglected Tropical Diseases 9 (8): e0004031. doi:10.1371/journal.pntd.0004031.

 

Balzarini J, Das K, Bernatchez JA, Martinez SE, Ngure M, Keane S, Ford A, Maguire N, Mullins N, John J, Kim Y, Dehaen W, Vande Voorde J, Liekens S, Naesens L, Götte M, Maguire AR, Arnold E (2015) Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics. Proc Natl Acad Sci U S A. Mar 17;112(11):3475-80

 

Barakat K (2015) Editorial:  Immune Checkpoints Inhibitors: The Search For A Single Antiviral & Anticancer Magic Bullet. J Pharma Care Health Sys. 2:e125.

 

Berghold VM, Gauster M, Hemmings DG, Moser G, Kremshofer J, Siwetz M, Sundl M, Huppertz B. (2015) “Phospholipid scramblase 1 (PLSCR1) activity negatively regulates villous trophoblast fusion,” Histochemistry and Cell Biology, Apr;143(4):381-96. doi: 10.1007/s00418-014-1294-y. Epub 2014 Nov 2.

 

B. Becker, J.M. Doan, B. Wustman, E.J. Carpenter, L. Chen, Y. Zhang, G.K. Wong, M. Melkonian. (2015). The origin and evolution of the plant cell surface: algal integrin-associated proteins and a new family of integrin-like cytoskeleton-ECM linker proteins. Genome Biol. Evol. 7: 1580-1589. PMID: 25977459. DOI: 10.1093/gbe/evv089

 

S. Belga and K. Doucette. (2015) Hepatitis C in Non-Hepatic Solid Organ Transplant Candidates and Recipients: A New Horizon. World Journal of Gastroenterology. In Press 2015.

 

Benesch MGK, Tang X, Dewald J, Dong W-F, Mackey JR, Hemmings DG, McMullen TPW, Brindley DN. “Tumor-induced inflammation in mammary adipose tissue stimulates a vicious cycle of autotaxin expression and breast cancer progression,” FASEB J, 29(9):3990-4000, 2015 (IF = 5.043)

 

B Berenger, K Doucette, S. Smith. (2015) Epidemiology and risk factors for nosocomial bloodstream infections in solid organ transplants over a 10-year period. Transplant Infectious Diseases. In Press 2015.

S. Benzekry, J. A Tuszynski, E. A Rietman and G. L Klement (2015) Design Principles for Cancer Therapy guided by changes in complexity of Protein-Protein Interaction Networks, Biology Direct 10:32 (2015), DOI 10.1186/s13062-015-0058-5, IF=4.04.

 

Bernatchez JA, Paul R, Tchesnokov EP, Ngure M, Beilhartz GL, Berghuis AM, Lavoie R, Li L, Auger A, Melnyk RA, Grobler JA, Miller MD, Hazuda DJ, Hecht SM, Götte M (2015) Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase.  J Biol Chem. Jan 16;290(3):1474-84

 

Blaine, A.H. D. Miranzo-Navarro, L.K. Campbell, J. R. Aldridge, R.G. Webster, and K.E. Magor. (2015) Duck TRIM27-L enhances MAVS signaling and is absent in chickens and turkeys. Molecular Immunology 67:607-15.

 

Blyth, G.A.D., W-F. Chan, R.G. Webster and K.E. Magor. (2015) Duck IFITM3 mediates restriction of influenza viruses. Journal of Virology 90 (1): 103-16.

 

Brockington SF, Yang Y, Gandia-Herrero F, Covshoff S, Hibberd JM, Sage RF, Wong GK, Moore MJ, Smith SA. (2015)

Lineage-specific gene radiations underlie the evolution of novel betalain pigmentation in Caryophyllales.

New Phytol. 2015 Sep;207(4):1170-80. doi: 10.1111/nph.13441. Epub 2015 May 13.

 

Brockington SF, Moyroud E, Sayou C, Monniaux M, Nanao MH, Thévenon E, Chahtane H, Warthmann N, Melkonian M, Zhang Y, Wong GK, Weigel D, Dumas R, Parcy F. (2015) Evolution. Response to Comment on “A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity”. Science. 6;347(6222):621. doi: 10.1126/science.1256011

 

S.F. Brockington, Y. Yang, F. Gandia-Herrero, S. Covshoff, J.M. Hibberd, R.F. Sage, G.K. Wong, M.J. Moore, S.A. Smith. (2015) Lineage-specific gene radiations underlie the evolution of novel betalain pigmentation in Caryophyllales. New Phytol. 207: 1170-1180. PMID: 25966996. DOI: 10.1111/nph.13441

 

Brownlie R, Kumar P, Babiuk LA, Tikoo SK. (2015) Recombinant Bovine Adenovirus-3 Co-Expressing Bovine Respiratory Syncytial Virus Glycoprotein G and Truncated Glycoprotein gD of Bovine Herpesvirus-1 Induce Immune Responses in Cotton Rats. Mol Biotechnol. 57(1):58-64. doi: 10.1007/s12033-014-9801-x.

 

Burak KW, Meeberg GA, Myers RP, Fick GH, Swain MG, Bain VG, Kneteman NM, Hilsden RJ. (2015) Validation, current use and future direction of the Model for End-stage Liver Disease for liver transplant allocation in Canada. Can J Gastroenterol Hepatol, June 15; pii: 16942.  [Epub ahead of print]

 

Burak KW, Sherman M, Kneteman N, Collaborators(13). (2015) Hepatocellular carcinoma: Consensus, controversies and future directions. A report   from the Canadian Association for the Study of the Liver Hepatocellular Carcinoma meeting. Can J Gastroenterol Hepatol May;29(4):178-184.

S.B. Cannon, M.R. McKain, A. Harkess, M.N. Nelson, S. Dash, M.K. Deyholos, Y. Peng, B. Joyce, C.N. Stewart Jr, M. Rolf, Kutchan T, Tan X, Chen C, Zhang Y, Carpenter E, Wong GK, Doyle JJ, Leebens-Mack J  (2015) Multiple polyploidy events in the early radiation of nodulating and nonnodulating legumes. Mol. Biol. Evol. 32: 193-210. PMID: 25349287. DOI: 10.1093/molbev/msu296

 

H. Cao, H. Wu, R. Luo, S. Huang, Y. Sun, X. Tong, Y. Xie, B. Liu, H. Yang, H. Zheng, … Y. Li, G.K. Wong, J. Wang. (2015)  De novo assembly of a haplotype-resolved human genome. Nat. Biotechnol. 33: 617-622. PMID: 26006006. DOI: 10.1038/nbt.3200

 

Cardoso FS, Bagshaw SM, Abraldes JG, Kneteman NM, Meeberg G, Fidalgo P, Karvellas CJ. (2015) Comorbidities have a limited impact on post-transplant survival in carefully selected cirrhotic patients: a population-based cohort study. Ann Hepatolog. July/August;14(4):505-14

Cardoso FS, Karvellas CJ, Kneteman NM, Meeberg G, Fidaigo P, Bagshaw SM. (2015) Postoperative resource utilization and survival among liver transplant recipients with Model for end-stage liver disease score >=40: A retrospective cohort study. Can J Gastroenterol Hepatol  May;29(4):185-191.

 

N. Carels, L. B. Spinassé, T. M. Tilli, J. A. Tuszynski (2015) Toward precision medicine of breast cancer. Theoretical Biology and Computational Medicine (accepted with minor corrections December 20, 2015), IF=0.95

 

Chen R, Kobewka M, Addison W, LaChance G, Tyrrell DLJ.     Intrinsic Viral Factors are the Dominant Determinants of the Hepatitis C Virus Response to Interferon Alpha Treatment in Chimeric Mice.  PlosOne. Accepted. December 2015

 

C. D.M. Churchill, M. Klobukowski and J.A. Tuszynski (2015) Analysis of the binding mode of laulimalide to microtubules: Establishing a laulimalide-tubulin  pharmacophore, Journal of Biomolecular Structure & Dynamics, (accepted for publication, July 27, 2015) IF=2.919

 

C.D. M. Churchill, M. Klobukowski and J.A. Tuszynski (2015) Elucidating the mechanism of action of the clinically-approved  taxanes: A comprehensive comparison of local and allosteric effects, Chemical Biology & Drug Design  Nov. 85(5) 1253-66 (2015), IF=2.527.

 

M. Cocchi, C. Minuto, L. Tonello and J. A. Tuszynski (2015) Connection Between the Linoleic Acid in the Brain and Psychopathology: Quantum Symmetry Breaking in the Brain? Open Journal of Depresssion 4, 41-52 (2015) IF=0.84

 

Conroy AL, Hawkes M, Hayford K, Namasopo S, Opoka RO, John CC, Liles WC, Kain KC. (2015) Prospective validation of pediatric disease severity scores to predict mortality in Ugandan children presenting with malaria and non-malaria febrile illness. Crit Care. 2015 Feb 23;19:47.

 

Conroy AL, Gélvez M, Hawkes M, Rajwans N, Tran V, Liles WC, Villar-Centeno LA, Kain KC. (2015) Host biomarkers are associated with progression to dengue haemorrhagic fever: a nested case-control study. Int J Infect Dis. Aug 6

 

Cordell HJ, Han Y, Mells GF, Li Y, Hirschfield GM, Greene CS, Xie G, Juran BD, Zhu D, Qian DC, Floyd JA, Morley KI, Prati D, Lleo A, Cusi D; Canadian-US PBC Consortium (A Mason); Italian PBC Genetics Study Group; UK-PBC Consortium, Gershwin ME, Anderson CA, Lazaridis KN, Invernizzi P, Seldin MF, Sandford RN, Amos CI, Siminovitch KA (2015) International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways. Nature Communications 22;6:8019. doi: 10.1038/ncomms9019.

 

Cooper T, Biron B, Fast D, Tam R, Carey T, Shmulevitz, M*, Seikaly H* (2015) Oncolytic activity of reovirus in HPV positive and negative head and neck squamous cell carcinoma. J Otolaryngol Head Neck Surg. 2015 Feb 24;44:8. doi: 10.1038/onc.2015.136. (*corresponding authors)

 

T.J.A. Craddock, S.R. Hameroff and J.A. Tuszynski, (2015) The Quantum Underground- Where Mind and Life Originate, 58 pages, in R. Poznanski, J.A. Tuszynski and T. Feinberg  (eds.), The Biophysics of Consciousness: A Foundational Approach, World Scientific,

 

Dai YC, Zhang XF, Xia M, Tan M, Quigley C, Lei W, Fang H, Zhong W, Lee B, Pang X, Nie J, Jiang X. (2015) Antigenic Relatedness of Norovirus GII.4 Variants Determined by Human Challenge Sera. PLoS One. Apr 27;10(4):e0124945. eCollection 2015. PubMed PMID: 25915764; PubMed Central PMCID: PMC4411064.

 

P.M. Delaux, G.V. Radhakrishnan, D. Jayaraman, J. Cheema, M. Malbreil, J.D. Volkening, H. Sekimoto, T. Nishiyama, M. Melkonian, L. Pokorny, G.K. Wong et al. (2015). Algal ancestor of land plants was preadapted for symbiosis. Proc. Natl. Acad. Sci. USA. 112: 13390-13395. PMID: 26438870. DOI: 10.1073/pnas.1515426112

 

Demczuk, W., T. Lynch, I. Martin, G. Van Domselaar, M. Graham, A. Bharat, V. Allen, L. Hoang, B. Lefebvre, G.J. Tyrrell, G. Horsman, D. Haldane, R. Garceau, J. Wylie, T. Wong, and M. Mulvey (2015) Whole-genome phylogenetic heterogeneity of Neisseria gonorrhoeae with decreased cephalosporin susceptibility collected in Canada between 1989 and 2013. Journal of Clinical Microbiology. 53(1):191-200. PMID:25378573.

 

M. Deriu, G. Grasso, J.A. Tuszynski, D. Gallo, U. Morbiducci and A. Danani, Josephin Domain (2015) Structural Conformations Explored by Metadynamics in Essential Coordinates, PLoS Computational Biology (accepted December 15, 2015) IF=4.867.

 

Dore G, Lawitz E, Hézode C, Shafran SD, Ramji A, Tatum HA, Taliani G, Tran A, Brunetto MR, Zaltron S, Strasser SI, Weis N, Ghesquiere W, Lee SS, Larrey D, Pol S, Harley H, George J, Fung S, de Lédinghen V, Hagens P, McPhee F, Hernandez D, Cohen D, Cooney E, Noviello S, Hughes EA. (2015) Daclatasvir and peginterferon/ribavirin has higher efficacy with shorter treatment duration for hepatitis C virus genotype 2 or 3 infection. Gastroenterology 148:355-66.

 

Douglas DN, Pu CH, Lewis JT, Logan M, Lund G, Addison WR, Bhat R, Anwar-Mohamed A, Lehner R, Kneteman NM.  (2015) Oxidative stress attenuates lipid synthesis and increases mitochondrial fatty acid oxidation in hepatoma cells infected with hepatitis C virus. J Biol Chem. Dec 1. pii: jbc.M115.674861. [Epub ahead of print]

 

Douglas D, Kneteman NM. (2015) Generation of improved mouse models for the study of hepatitis C virus. European Journal of Pharmacology. July  15;759: 313-325.  Review.

 

Drews SJ, Simmonds K, Usman HR, Yee K, Fathima S, Tipples G, Tellier R, Pabbaraju K, Wong S, Talbot J. (2015) Characterization of enterovirus activity, including that of enterovirus D68, in pediatric patients in Alberta, Canada, in 2014. J Clin Microbiol. 2015 Mar;53(3):1042-5. doi: 10.1128/JCM.02982-14. Epub 2015 Jan 14.

 

H. DuanMu, Y. Wang, X. Bai, S. Cheng, M.K. Deyholos, G.K. Wong, D. Li, D. Zhu, R. Li, Y. Yu, et al. (2015) Wild soybean roots depend on specific transcription factors and oxidation reduction related genesin response to alkaline stress. Funct. Integr. Genomics 15: 651-660. PMID: 25874911. DOI: 10.1007/s10142-015-0439-y

 

Egli A, Humar A, Widmer LA, Lisboa LF, Santer DM, Mueller T, Stelling J, Baluch A, O’Shea D, Houghton M, Kumar D. (2015) Effect of Immunosuppression on T-Helper 2 and B-Cell Responses to Influenza Vaccination. J Infect Dis. Jul 1;212(1):137-46. doi: 10.1093/infdis/jiv015. Epub 2015 Jan 14.

 

R.M. A. El-Magd, B. Griffith, N.F. Vozza, J.A. Tuszynski and D. S. Wishart (2015) Isolation of soluble scFv antibody fragments specific for small biomarker molecule, L-Carnitine, using phage display, Journal of Immunological Methods (accepted November 18, 2015) IF=1.82.

 

Feld JJ, Jacobson IM, Hezode CH, Asselah T, Ruane PJ, Gruener N, Abergal A, Mangia A, Lai C-L, Chan HLY, Mazzotta F, Moreno C, Yoshida E, Shafran SD, Towner WJ, Tran TT, McNally J, Osinusi A, Svarovskaia E, Zhu Y, Brainard DM, McHutchinson JG, Agarwal K, Zeuzem S, for the ASTRAL-1 Investigators. (2015) Sofosbuvir and velpatasvir for HCV genotype 1,2,4,5, and 6 infection. N Engl J Med 373:2599-607.

 

Freedman SB, Lee BE, Louie M, Pang XL, Ali S, Chuck A, Chui L, Currie GR, Dickinson J, Drews SJ, Eltorki M, Graham T, Jiang X, Johnson DW, Kellner J, Lavoie M, MacDonald J, MacDonald S, Svenson LW, Talbot J, Tarr P, Tellier R, Vanderkooi OG. (2015) Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE): epidemiology, emerging organisms, and economics. BMC Pediatr. Jul 31;15:89. doi: 10.1186/s12887-015-0407-7

 

D. Friesen, V. Baracos and J.A. Tuszynski (2015) Modeling the energetic cost of cancer as a result of altered energy metabolism: implications for cachexia, Theoretical Biology and Computational Medicine 2015, 12:17  doi:10.1186/s12976-015-0015-0 IF=1.27

 

Friesen DE, Craddock TJ, Kalra AP, Tuszynski JA. (2015) Biological wires, communication systems, and implications for disease. Biosystems. Jan;127C:14-27. doi: 10.1016/j.biosystems.2014.10.006. Epub 2014 Nov 4. Review.

Galenza, A., Hutchinson, J., Hazes, B., Campbell, S., and Foley E. (2015) Glucose modulates Drosophila longevity and immunity independent of the microbiota. BioRxiv doi: http://dx.doi.org/10.1101/027326. Accepted by Open Biology. Research funded by CIHR.

 

Garant K, Shmulevitz M, Pan L, Daigle R, Ahn DG, Gujar S, Lee PW. (2015)  “Oncolytic reovirus induces intracellular redistribution of Ras to promote apoptosis and progeny virus release.  Oncogene May 11. doi: 10.1038/onc.2015.136.

 

Geissler E, Schnitzbauer AA, Zulke C, Lamby PE, Proneth A, Duvoux C, Burra P, Jauch, KW, Rentsch M, Ganten TM, Schmidt J, Settmacher U, Heise M, Rossi G, Cillo U, Kneteman N, Adam R, van Hoek B, Bachellier P, Wold P, Rostaing L, Bechstein WO, Rizell M, Powell J, Hidalgo E, Gugenheim J, Wolters H, Brockmann J, Roy A, Mutzbauer I, Schlitt A, Beckebaum S, Graeb C, Nadalin S, Valente U, Schanez Turrion V, Jamieson N, Scholz T, colledan M, Fandrich F, Becker T, Soderdahl G, Chazouilleres, Makisola H, Pageaux GP, Steininger R, Soliman T, de Jong KP, Pirenne J, Margreiter R, Pratschke J, Pinna AD, Hauss J, Schreiber S, Strasser S, Klempnauer J, Troisi RL, Bhoori S, Lerut J, Bilbao I, Klein CG, Konigsrainer A, Mirza Daruis, Otto G, Mazzaferro V, Neuhaus P, Schlitt HJ. (2015) Sirolimus use in liver transplant recipients with hepatocellular carcinoma: A randomized, multi-centre, open-label phase 3 trial. Transplantation Nov 12 [Epub ahead of print].

 

F. Gentile, M. Deriu, G. Licandro, A. Prunotto, A. Danani, J. A. Tuszynski (2015) Structure Based Modeling of Small Molecules Binding to the TLR7 by Atomistic Level Simulations, Molecules 20, 8316-8340; doi:10.3390/molecules20058316, IF=2.095.

 

Good MF, Hawkes MT, Yanow SK. (2015) Humanized Mouse Models to Study Cell-Mediated Immune Responses to Liver-Stage Malaria Vaccines. Trends Parasitol. 2015 Nov;31(11):583-94.

 

Good, M.F., M. Pandey, M.R. Batzloff and G.J. Tyrrell. (2015) Strategic development of the conserved region of the M protein and other candidates as vaccines to prevent infection with Group A streptococci. Expert Review of Vaccines. 14(11):1459-1470. PMID:26485214.

 

Gopal K, Gupta N, Zhang H, Alshareef A, Alqahtani H, Bigras G, Lewis J, Douglas D, Kneteman N, Lavasanifar A, Lai R.  (2015) Oxidative stress induces the acquisition of cancer stem-like phenotype in breast cancer detectable by using a Sox2 regulatory region-2 (SRR2) reporter. Oncotarget  Dec 16. doi: 10.18632/oncotarget.6630. [Epub ahead of print]

 

Gounder, P.P., T. Zulz, S. Desai, F. Stenz, K. Rudolph, R. Tsang, G.J. Tyrrell and M.G. Bruce. (2015) Epidemiology of meningitis caused by Haemophilus influenzae, Neisseria meningitdis and Streptococcus pneumoniae in North American Arctic, 2000-2010. Journal of Infection. 71(2):178-187. PMID:25864638.

 

G. Grasso, M. A. Deriu, J. A. Tuszynski, D. Gallo, U. Morbiducci, and A. Danani (2015) Conformational Fluctuations of the AXH monomer of Ataxin-1, Proteins: Structure, Function, and Bioinformatics (accepted, October 19, 2015), IF=2.627

 

Guntermann S., Fraser B., Hazes B., Foley E. (2015). Independent Proteolytic Activities Control the Stability and Size of Drosophila Inhibitor of Apoptosis 2 Protein. J Innate Immun. 7 (5):518-529.

 

Guntermann, S., Fraser, B., Hazes, B., and Foley, E. (2015) Caspase Activation and Activity in the Drosophila Immune Deficiency Pathway. J Innate Immunity. 7(5): 518-29.

Haile Y, Carmine-Simmen K, Olechowski C, Kerr B, Bleackley RC, Giuliani F.  (2015) Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivoJ Neuroinflammation. Sep 4;12:157.

 

Hamula, C.L.A., H. Peng, Z. Wang, A.M. Newbigging, G.J. Tyrrell, X.F. Li and X.C. Le. (2015) The effects of SELEX conditions on the resultant aptamer pools in the selection of aptamers binding to bacterial cells. Journal of Molecular Evolution. 81(5-6):194-206. PMID:26538121.

 

Hatchette TF, Drews SJ, Grudeski E, Booth T, Martineau C, Dust K, Garceau R, Gubbay J, Karnauchow T, Krajden M, Levett PN, Mazzulli T, McDonald RR, McNabb A, Mubareka S, Needle R, Petrich A, Richardson S, Rutherford C, Smieja M, Tellier R, Tipples G, LeBlanc JJ. (2015) Detection of enterovirus D68 in Canadian laboratories. J Clin Microbiol. May;53(5):1748-51. doi: 10.1128/JCM.03686-14. Epub 2015 Mar 4.

 

Hawkes MT, Forgie S, Brophy J, Crockett M. (2015) Artesunate treatment of severe pediatric malaria: A review of parasite clearance kinetics and clinical implications. Can J Infect Dis Med Microbiol. 2015 Sep-Oct;26(5):237-40.

 

Hawkes MT, Conroy AL, Opoka RO, Hermann L, Thorpe KE, McDonald C, Kim H, Higgins S, Namasopo S, John C, Miller C, Liles WC, Kain KC. (2015) Inhaled nitric oxide as adjunctive therapy for severe malaria: a randomized controlled trial. Malar J. 2015 Oct 29;14(1):421.

 

Hawkes M, Conroy AL, Opoka RO, Namasopo S, Zhong K, Liles WC, John CC, Kain KC. (2015) Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011-2013. Emerg Infect Dis. 2015 Jul;21(7):1237-9.

 

Hayden RT, Preiksaitis J, Tong Y, Pang X, Sun Y, Tang L, Cook L, Pounds S, Fryer J, Caliendo AM. (2015) Commutability of the First World Health Organization International Standard for Human Cytomegalovirus. J Clin Microbiol. 2015 Oct;53(10):3325-33

 

M. Healey, M. Woodside and J.A. Tuszynski (2015) Phase Transitions and Structure Analysis in Wild- Type, A30P, E46K, and A53T Mutants of ɑ-Synuclein, European Biophysics Journal (accepted November 18, 2015), IF=2.219

 

R. Hellinger, J. Koehbach, D.E. Soltis, E.J. Carpenter, G.K. Wong, C.W. Gruber. (2015) Peptidomics of circular cysteine-rich plant peptides: Analysis of the diversity of cyclotides from Viola tricolor by transcriptome and proteome mining. J. Proteome Res. 14: 4851-4862. PMID: 26399495. DOI: 10.1021/acs.jproteome.5b00681

 

Hézode C, Hirschfield GM, Ghesquiere W, Sievert W, Rodriguez-Torres M, Shafran SD, Thuluvath PJ, Tatum HA, Waked I, Esmat G, Lawitz EJ, Rustgi VK, Pol S, Wels N, Pockros PJ, Bourliere M, Serfaty L, Vierling JM, Fried MW, Weiland O, Brunetto MR, Everson GT, Zeuzem S, Kwo PY, Sulkowski M, Bräu N, Hernandez D, McPhee F, Wind-Rotolo M, Liu Z, Noviello S, Hughes EA, Yin PD, Schnittman S. (2015) Daclatasvir plus peginterferon alfa and ribavirin for treatment-naïve chronic hepatitis C genotype 1 or 4: a randomized study. Gut 64:948-56.

 

P. Hinow, E.A. Rietman, S.I. Omar and J.A. Tuszynski (2015) Algebraic and Topological Indices of Molecular Pathway Networks in Human Cancers, Mathematical Biosciences and Engineering vol. 12, No. 6, December pp. 1289-1302 (2015) IF=0.866

 

G. Hirschfield, AL Mason, V. Luketic, K Lindor, S. Gordon, M. Mayo, K. Kowdley, C. Vincent, H. Bodhenheimer, A. Parés, M. Trauner, H. Marschall, L. Adorini, C. Sciacca, T. Beecher-Jones, E. Castelloe, O. Böhm, D. Shapiro (2015) Efficacy of Obeticholic Acid in Patients with Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid.. Gastroenterology 148:751-761

 

J.D. Hollister, S. Greiner, W. Wang, J. Wang, Y. Zhang, G.K. Wong, S.I. Wright, M.T. Johnson. (2015) Recurrent loss of sex is associated with accumulation of deleterious mutations in Oenothera. Mol. Biol. Evol. 32: 896-905. PMID: 25534028. DOI: 10.1093/molbev/msu345

 

Hu Q and Baldwin TA. (2015) Differential roles for Bim and Nur77 in thymocyte clonal deletion induced by ubiquitous self-antigen. The Journal of Immunology. 194(6): 2643-53

 

Islam A, Schulz S, Afroz S, Babiuk LA, van Drunen Littel-van den Hurk S. (2015) Interaction of VP8 with mRNAs of bovine herpesvirus-1. Virus Res. Feb 2;197:116-26. doi: 10.1016/j.virusres.2014.12.017. Epub 2014 Dec 18.

 

Jacobson I, Zeuzem S, Flisiak R, Knysz B, Lueth S, Zarebska-Michaluk D, Janczewska E, Ferenci P, Diago M, Zignego AL, Safadi R, Baruch Y, Abdurakhmanov D, Shafran S, Thabut D, Bruck R, Gadano A, Thompson AJ, Kopit J, McPhee F, Michener T, Hughes E, Yin PD, Noviello S. (2015) Daclatasvir versus telaprevir plus peginterferon alfa/ribavirin for HCV genotype 1. World J Hepatol (in press).

 

A.Jandová, J. Pokorný, J. Pokorný, J. Kobilková, M. Nedbalova, A. Čoček, F. Jelínek, J. Vrba, J.
Vrba (Jr.), A. Dohnalova, J. Kytnarová, J.A. Tuszyński and A. Foletti (2015) Diseases Caused by Defects of Energy Level and Loss of Coherence in Living Cells, Electromagnetic Biology and Medicine Volume 34 (2) – Jun 1, 2015, IF=1.194.

 

Jeremy A. Hirota, David J. Marchant, Gurpreet K. Singhera, Fatemeh Moheimani, Delbert R. Dorscheid, Chris Carlsten, Don D. Sin, Darryl A. Knight. (2015) Urban particulate matter increases human airway epithelial cell IL-1β secretion following scratch wounding and H1N1 influenza A exposure in vitro. Experimental Lung Research,  In press.

 

Jung K, Gupta N, Wang P, Lewis J, Gopal K, Wu F, Ye X, Alshareef A, Abdulkarim B, Douglas D, Kneteman N, Lai R. (2015) Triple negative breast cancers comprise a highly turorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulartory region 2 (SRR2) reporter. Oncotarget  Apr 30;6(12):10366-7320.

 

Kassem S, Marawan A, El-Sheikh S, Barakat KH (2015) Entropy In Bimolecular Simulations: A Comprehensive Review Of Atomic Fluctuations-Based Methods. J Mol Graph Model (Accepted).

 

C.D.Katsetos, M. J. Reginato, L. D’Agostino, A. Legido, P. W. Baas, J.A. Tuszyński, E. Dráberová, and P. Dráber (2015) Emerging Microtubule Targets in Glioma Therapy, Seminars in Pediatric Neurology, DOI: http://dx.doi.org/10.1016/j.spen.2015.03.009, March 2015, vol. 22 (issue 1) pp. 49-72 (2015) IF=1.883.

 

A.Kuban-Jankowska, M. Gorska, J.A. Tuszynski, C. Churchill, P. Winter, M. Klobukowski and M.
Woźniak (2015) Inactivation of protein tyrosine phosphatases by peracids correlates with the hydrocarbon chain length, Cellular Physiology and Biochemistry, 36:1069-1083

 

A. Kuban-Jankowska, K. K. Sahu, M. Gorska, J. A. Tuszynski and M. Wozniak (2015) Chicoric acid properties to prevent infection by decrease the activity of YopH virulence factor, Microbiology and Immunology (accepted November 27, 2015), IF=1.242

 

A. Kuban-Jankowska, M. Gorska, L. Jaremko, M. Jaremko, J. A. Tuszynski and M. Wozniak (2015) The physiological concentration of ferrous iron (II) alters the inhibitory effect of hydrogen peroxide on CD45, LAR and PTP1B phosphatases, Biometals (accepted September 22, 2015), IF=2.503

 

A. Kuban-Jankowska, K. Sahu, P. Niedzialkowski, M. Gorska, J.A. Tuszynski, T. Ossowski, and M.Wozniak (2015) Redox process is crucial for inhibitory properties of aurintricarboxylic acid against activity of YopH – virulence factor of Yersinia pestis, Oncotarget, vol. 6, no. 21 pp. 18364-18373, IF=6.63

 

Lai FY, Dover DC, Lee B, Fonseca K, Solomon N, Plitt SS, Jaipaul J, Tipples GA, Charlton CL. (2015) Determining rubella immunity in pregnant Alberta women 2009-2012. Vaccine. 2015 Jan 29;33(5):635-41. doi: 10.1016/j.vaccine.2014.12.022. Epub 2014 Dec 19.

 

W. Lammers, G. Hirschfield, C. Corpechot, F. Nevens, J. Talkwalkar, H. Janssen, A. Floreani, C. Ponsioen, M. Mayo, P. Invernizzi, P. Battezzati, A. Parés, A. Burroughs,, A. Mason, K. Kowdley, T. Kumagi, M. Harms, P. Trivedi, R. Poupon, A. Cheung, A. Lleo, K. Lindor, B. Hansen, H. van Buuren (2015) Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy. Gastroenterology in press 10.1053/j.gastro.2015.07.061

 

Landi A, Broadhurst D, Vernon SD, Tyrrell DLJ, Houghton M.  Reductions in circulating levels of I-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome.  Cytokine 2015. Nov 23: 78:27-36.  Doi: 10.1016/j.cyto.2015.11.018. (Epub ahead of print)

 

F.W. Li, C.J. Rothfels, M. Melkonian, J.C. Villarreal, D.W. Stevenson, S.W. Graham, G.K. Wong, S. Mathews, K.M. Pryer. (2015). The origin and evolution of phototropins. Front. Plant Sci. 6: 637. PMID: 26322073. DOI: 10.3389/fpls.2015.00637

 

F.W. Li, M. Melkonian, C.J. Rothfels, J.C. Villarreal, D.W. Stevenson, S.W. Graham, G.K. Wong, K.M. Pryer, S. Mathews. (2015) Phytochrome diversity in green plants and the origin of canonical plant phytochromes. Nat. Commun. 6: 7852. PMID: 26215968. DOI: 10.1038/ncomms8852

 

C.S. Lin, J.J. Chen, Y.T. Huang, M.T. Chan, H. Daniell, W.J. Chang, C.T. Hsu, D.C. Liao, F.H. Wu, S.Y. Lin, Liao CF, Deyholos MK, Wong GK, Albert VA, Chou ML, Chen CY, Shih MC (2015). The location and translocation of ndh genes of chloroplast origin in the Orchidaceae family. Sci. Rep. 5: 9040. PMID: 25761566. DOI: 10.1038/srep09040

 

Lineker C, Kerr PM, Nguyen P, Bloor I, Astbury S, Patel N, Budge H, Hemmings DG, Plane F, Symonds ME, Bell RC. “High fructose consumption in pregnancy alters the perinatal environment without increasing metabolic disease in the offspring,” Reproduction, Fertility and Development, 2015 Jul 6

 

Lisboa LF, Egli A, O’Shea D, Åsberg A, Hartmann A, Rollag H, Pang XL, Tyrrell DL, Kumar D, Humar A. (2015) Hcmv-miR-UL22A-5p: A Biomarker in Transplantation With Broad Impact on Host Gene Expression and Potential Immunological Implications. Am J Transplant. Apr 1. doi: 10.1111/ajt.13222. [Epub ahead of print]

 

Lopez-Orozco, J., Pare, J.M., Holme, A.L., Chaulk, S.G., Fahlman, R.P. and Hobman, T.C. (2015) Functional analyses of phosphorylation events in human Argonaute 2. RNA 21: 2030-8. doi: 10.1261/rna.053207.115.

 

M.J. Lyu, U. Gowik, S. Kelly, S. Covshoff, J. Mallmann, P. Westhoff, J.M. Hibberd, M. Stata, R.F. Sage, H. Lu, Wei X, Wong GK, Zhu XG (2015) RNA-Seq based phylogeny recapitulates previous phylogeny of the genus Flaveria (Asteraceae) with some modifications. BMC Evol. Biol. 15: 116. PMID: 26084484. DOI: 10.1186/s12862-015-0399-9

 

Mackenzie-Dyck S, Latimer L, Atanley E, Kovacs-Nolan J, Attah-Poku S, Babiuk LA, van Drunen Littel-van den Hurk S. (2015) Immunogenicity of a bovine herpesvirus 1 glycoprotein d DNA vaccine complexed with bovine neutrophil Beta-defensin 3. Clin Vaccine Immunol. 22(1):79-90. doi: 10.1128/CVI.00476-14. Epub 2014 Nov 5.

 

Mahrooghy, S. Yarahmadian, V. Menon, V. Reazania and J.A. Tuszynski (2015) The use of compressive sensing and peak detection in the reconstruction of microtubule length time series in the process of dynamic instability, DOI: http://dx.doi.org/10.1016/j.compbiomed.2015.07.014, Computers in Biology and Medicine (2015), IF=1.240

 

Manning Fox J, Lyon J, Dai XQ, Wright R, Hayward J, van de Bunt M, Kin T, Shapiro J, McCArthy M, Gloyn A, Ungrin M, Lakey J, Kneteman N, Warnock G, Korbutt G, Rajotte R, MacDonald P. (2015) Human islet function following twenty years of cryogenic biobanking.  Diabetologia. Open access 01 May 2015

 

Marcet-Palacios M, Ewen C, Pittman E, Duggan B, Carmine-Simmen K, Fahlman RP, Bleackley RC. (2015) Design and characterization of a novel human Granzyme B inhibitor. Protein Eng Des Sel. 2015 Jan;28(1):9-17. doi: 10.1093/protein/gzu052. Epub 2014 Dec 9.

 

Marquez, E and Kane, K. (2015). Identities of P2 and P3 residues of H-2Kb-bound peptides determine mouse Ly49C recognition. PLoS One. 10(7): 0-0.

 

Martin LJ, Lee BE, Yasui Y.  (2015) Google Flu Trends in Canada: A comparison of digital disease surveillance data with physician consultations and respiratory virus surveillance data, 2010-14. Epidemiol Infect. Epub.2015  http://dx.doi.org/10.1017/S0950268815001478

 

McKillop SJ, Belletrutti MJ, Lee BE, Yap JY, Noga ML, Desai SJ, Sergi C. (2015)  Adenovirus necrotizing hepatitis complicating atypical teratoid rhabdoid tumor. Pediatr Int. Oct;57(5):974-7. doi: 10.1111/ped.12674. Epub 2015 Aug 19. PubMed PMID: 26508178

 

Mehta N, Taylor J, Quilty D, Barry M. (2015) Ectromelia virus encodes an anti-apoptotic protein that regulates cell death. Virology. 2015 Jan 15;475:74-87. doi: 10.1016/j.virol.2014.10.023. Epub 2014 Nov 26.

 

Members of the Canadian Public Health Laboratory Network Syphilis Laboratory Task Group during authorship (co-chairs and membership in alphabetical order), Tsang RS, Morshed M, Allen V, Chernesky MA, Fonseca K, Garceau R, Jayaraman GC, Kadkhoda K, Lee BE, Levett PN, Radons SM, Serhir B, Singh AE, Wong T. (2015) Canadian Public Health Laboratory Network national syphilis laboratory testing recommendations: INTRODUCTION. Can J Infect Dis Med Microbiol. Jan-Feb;26(Suppl A):4A-5A. PubMed PMID: 25798164; PubMed Central PMCID: PMC4353978.

 

Mohamed A, Johnston R, Shmulevitz, M. (2015). Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus Variants. Viruses (Review) Dec 1;7(12):6251-78. doi: 10.3390/v7122936

 

Mohamed A, Teicher C, Haefliger S, Shmulevitz M. (2015) Reduced virion-associated σ1 fibers on oncolytic reovirus variants promotes adaptation towards tumorigenic cells. J Virol. 89(8): 4319-4334. doi: 10.1128/JVI.03651-14

 

Nyende S, Conroy A, Opoka RO, Namasopo S, Kain KC, Mpimbaza A, Bhargava R, Hawkes M. (2015) Solar-powered oxygen delivery: study protocol for a randomized controlled trial. Trials. 2015 Jul 9;16:297.

 

O’Shea D, Law J, Egli A, Douglas D, Lund G, Forester S, Lambert J, Law M, Burton DR, Tyrrell DL, Houghton M, Humar A, Kneteman N. (2015) Prevention of HCV infection using a broad cross-neutralizing monoclonal antibody (AR4A) and Epigallocatechin-Gallate. Liver Transpl. 2015 Sep 21. doi: 10.1002/lt.24344. [Epub ahead of print]

 

Pabbaraju K, S Wong, SJ Drews, G Tipples and R Tellier. (2015) Full genome analysis of enterovirus D-68 strains circulating in Alberta, Canada. J Med Virol  Dec 8. doi: 10.1002/jmv.24444. [Epub ahead of print]

Pang X, Lee BE. (2015) Laboratory Diagnosis of Noroviruses: Present and Future. Clin Lab Med. Jun;35(2):345-362.

 

T. Perry, J. Jovel, J. Patterson, G.K. Wong, R.N. Fedorak, A. Thiesen, B. Dicken, K.L. Madsen. (2015) Fecal microbial transplant after ileocolic resection reduces ileitis but restores colitis in IL-10 -/- mice. Inflamm. Bowel Dis. 21: 1479-1490. PMID: 26070001. DOI: 10.1097/MIB.0000000000000383

 

Peterson, S.W., I. Martin, W. Demczuk, A. Bharat, L. Hoang, J. Wylie, V. Allen, B. Lefebvre, G.J. Tyrrell, G. Horsman, D. Haldane, R. Garceau, T. Wong and M.R. Mulvey. (2015) Molecular assay for the detection of ciprofloxacin resistance in Neisseria gonorrhoeae from cultures and clinical nucleic acid amplification test (NAAT) specimens. Journal of Clinical Microbiology. 53(11):3606-3608. PMID:26292300.

 

Peterson, S.W., I. Martin, W. Demczuk, A. Bharat, L. Hoang, J. Wylie, V. Allen, B. Lefebvre, G.J. Tyrrell, G. Horsman, D. Haldane, R. Garceau, T. Wong and M. Mulvey. (2015) Molecular assay for the detection of genetic markers associated with decreased susceptibility to cephalosporins in Neisseria gonorrhoeae. Journal of Clinical Microbiology.53(7):2042-2048. PMID:25878350.

 

Piret J, Goyette N, Eckenroth BE, Drouot E, Götte M, Boivin G. (2015) Contrasting Effect of W781V and W780V Mutations in Helix N of Herpes Simplex Virus-1 and Human Cytomegalovirus DNA Polymerases on Antiviral Drug Susceptibility. Journal of Virology  Apr 15;89(8):4636-44

 

R. R. Poznanski, J.A. Tuszynsik and T.E. Feinberg (eds.), Biophysics of Consciousness: A Foundational Approach, ISBN 9789814644259, World Scientific, Singapore, (2015)

 

J. Preto, M. Pettini, and J. A. Tuszynski (2015) Role of electrodynamic interactions in long-distance biomolecular recognition, Physical Review E 91, 052710 – Published 22 May 2015, IF=2.352.

 

Qin L, Favis N, Famulski J, Evans DH. (2015) Evolution of and Evolutionary Relationships between Extant Vaccinia Virus Strains. J Virol. 2015 Feb 1;89(3):1809-24. doi: 10.1128/JVI.02797-14. Epub 2014 Nov 19.

 

Qiu Y, Lee BE, Neumann N, Ashbolt N, Craik S, Maal-Bared R, Pang X. (2015) Assessment of human virus removal during municipal wastewater treatment in Edmonton, Canada. J Appl Microbiol. Oct 16. doi: 10.1111/jam.12971. [Epub ahead of print]

 

Reid, C.R., Airo, A.M. and Hobman, T.C. (2015) The Virus-host Interplay: Biogenesis of +RNA Replication Complexes. Viruses 7: 4385-4413. doi: 10.3390/v7082825.

 

V. Rezania, D. Coombe and J. A. Tuszynski (2015) A physiologically-based  flow network model for hepatic drug elimination III: 2D/3D DLA lobule models, Theoretical Biology and Computational
M
edicine (accepted with minor corrections December 24, 2015), IF=0.95

 

E.A. Rietman, J. Platig, J. A. Tuszynski, G. L. Klement  (2015) Thermodynamic Measures of Cancer: Gibbs Free Energy and Entropy of Protein-Protein Interactions, Journal of Biological Physics (accepted with minor reevisions December 14, 2015), IF=1.286

 

Roggenbeck BA, Carew MW, Charrois GJ, Douglas DN, Kneteman NM, Lu X, Le XC, Leslie EM. (2015) Characterization of arsenic hepatobiliary transplrot using sandwich cultured human hepatocytes. Toxicol Sci  Jun;145(2):307-20  Epub 2015 Mar 9.

 

Rothfels CJ, Li FW, Sigel EM, Huiet L, Larsson A, Burge DO, Ruhsam M, Deyholos M, Soltis DE, Stewart CN Jr, Shaw SW, Pokorny L, Chen T, dePamphilis C, DeGironimo L, Chen L, Wei X, Sun X, Korall P, Stevenson DW, Graham SW, Wong GK, Pryer KM. (2015) The evolutionary history of ferns inferred from 25 low-copy nuclear genes. Am. J. Bot. 102: 1089-1107. PMID: 26199366. DOI: 10.3732/ajb.1500089

 

K. Sahu, M. Woodside and J.A. Tuszynski (2015) α-Synuclein dimer structures found from computational simulations, Biochimie (accepted July 12, 2015), IF=2.963

 

V. Salari, M. Sajadi, H. Bassereh, V. Rezania, M. Alaei and J.A. Tuszynski (2015) On the Classical Vibrational Coherence of Carbonyl Groups in the Selectivity Filter Backbone of the KcsA Ion Channel, J of Integrative Neuroscience Vol. 14, no. 2, 195-206 (2015), IF=1.121.

 

Sawatzky, P., G. Liu, J.R. Dillon, V. Allen, B. Lefebvre, L. Hoang, G.J. Tyrrell, P. van Caeseele, P. Levett, and I. Martin. (2015) Quality assurance for antimicrobial susceptibility testing of Neisseria gonorrhoeae in Canada 2003 to 2012. Journal of Clinical Microbiology. 53(11):3646-3649. PMID:26338862.

 

 

Shafran SD. (2015) Hepatitis C genotype 1 paradox: Cost per treatment is increasing, but cost per cure is decreasing. Can J Gastroenterol Hepatol 29:46-8.

 

Shafran SD. (2015) HIV co-infected have similar SVR rates as HCV mono-infected with DAAs: it’s time to end segregation and integrate HIV patients into HCV trials. Clin Infect Dis 61:1127-34.

 

Shafran SD. (2015) Live attenuated herpes zoster vaccine for HIV-infected adults. HIV Medicine 2015; Aug 27 [Epub ahead of print].

 

Shah G, Tse-Chang A, Cooper R, Robinson J, Zorzela L, Amirav I, Codesal MC, Dixit D, Hansen E, Hawkes M. (2015) Nodular Lung Lesions in a 10 Week-Old Infant. Pediatr Infect Dis J. 2015 May 9.

 

D. Sharon, M. Chen, G. Zhang, S. Girgis, D. Graham, C. McDougall, B. Subsin, S. Wasilenko, A. Montano-Loza, A. Mason. (2015) Impact of combination antiretroviral therapy in the NOD.c3c4 mouse model of autoimmune biliary disease. Liver International 35;1442-1450

 

Shigayeva, A., W. Rudnick, K. Green, G.J. Tyrrell, W. Demczuk, W. Gold, J. Gubbay, F. Jamieson, A. Plevneshi, S. Pong-Porter, S. Richardson, A. McGeer and the Toronto Invasive Diseases Network. (2015) Association of serotype with respiratory presentations of pneumococcal infection, Ontario, Canada, 2003-2011. Vaccine. Nov 18, 2015. PMID:26602266.

 

Shigayeva, A, W. Rudnick, K. Green, D. Chen, W. Demzcuk, W. Gold, J. Johnstone, I. Kitai, S. Krajden, R. Lovinsky, M. Muller, J. Powis, N. Rau, S. Walmsley, G.J. Tyrrell, A. McGeer. (2015) Invasive pneumococcal disease among immunocompromised persons: implications for vaccination programs. Clinical Infectious Diseases. 2015 Sep 9. PMID:26354970.

 

Shmulevitz M and Mohamed A. (2-15) Nogo to IFN by Ras. Cell Cycle (Invited News and Views). Aug 3;14(15):2392-3. doi: 10.1080/15384101.2015.1063310.

 

Simmonds, D.K.,  S. Fathima, L. Chui,M. Lovgren,P. Shook,M. Shuel, G. J. Tyrrell, R. Tsang, S.J. Drews.

(2015) Dominance of two genotypes of Bordetella pertussis during a period of increased pertussis activity in Alberta, Canada: January 2012 – August 2012. International Journal for Infectious Diseases. 29:223-225. PMID:25462185.

 

S. Siccardi, J.A. Tuszynski and A. Adamatzki (2015) Boolean gates on actin filaments, Physics Letters A, on-line September 24 2015. IF=1.683

 

Singaravelu R, O’Hara S, Jones D, Chen R, Taylor N, Srinivasan P, Quan C, Roy D, Steenbergen R, Kumar A, Lyn R, Ozcelik D, Rouleau Y,  Nguyen M, Rayner K, Hobman T, Tyrrell DLJ,  Russell R, Pezacki J.  MicroRNAs regulate the immunometabolic response to viral infection in the liver.  Nature Chemical Biology 2015 Oct 19. doi: 10.1038/nchembio.1940. [Epub ahead of print]

 

Singh AE, Levett PN, Fonseca K, Jayaraman GC, Lee BE. (2015) Canadian Public Health Laboratory Network laboratory guidelines for congenital syphilis and syphilis screening in pregnant women in Canada. Can J Infect Dis Med Microbiol. Jan-Feb;26(Suppl A):23A-8A. PubMed PMID: 25798162; PubMed Central PMCID: PMC4353984.

 

Stamatikos AD, da Silva RP, Lewis JT, Douglas DN, Kneteman NM, Jacobs RL, Paton CM. (2015) Tissue specific effects of dietary carbohydrates and obesity on ChREBPα and ChREBPβ expression. Lipids  November 09 [Epub ahead of print].

 

M. St. George, A. T. Ayoub, A. Banerjee, C. Churchill, P. Winter, M. Klobukowski, C. Cass, R.

Ludueña, J. A. Tuszynski and S. Damaraju (2015) Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells, PLoS One, 23 pages, DOI:10.1371/journal.pone.0129168 June 8, 2015 IF=3.534.

 

Tang JW, Trivedi PJ, Lammers WJ, van Buuren HR, Parés A, Floreani A, Janssen HL, Invernizzi P, Battezzati PM, Ponsioen CY, Corpechot C, Poupon R, Mayo MJ, Burroughs AK, Nevens F, Mason AL, Kowdley KV, Lleo A, Caballeria L, Lindor KD, Hansen BE, Hirschfield GM; On behalf of the Global PBC Study Group. (2015) Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: a multicentre international study. Gut. 2015 Jan 7. pii: gutjnl-2014-308351. doi: 10.1136/gutjnl-2014-308351. [Epub ahead of print]

 

T. Tilli, N. Carels and J.A. Tuszynski (2015) Optimization of combination chemotherapy based on the calculation of network entropy for protein-protein interactions in breast cancer cell lines, European Physical Journal Nonlinear Biomedical Physics 3:6

 

L. Tonello, M. Cocchi, F. Gabrielli and J.A. Tuszynski (2015) On the possible quantum role of serotonin in consciousness, Journal of Integrative Neuroscience vol. 14, no. 3 pp. 295-308 (2015), IF=1.121.

 

YP Tong, B E Lee, XL Pang (2015)  Rapid genotyping of human rotavirus using SYBR green real-time reverse transcription-polymerase chain reaction with melting curve analysis. World J Virol  November 12; 4(4): 000-000

 

Toso C, Meeberg G, Hernandez-Alejandro R, Dufour JF, Marotta P, Majno P, Kneteman N. (2015) Total tumor volume and alpha fetoprotein for selection of transplant candidates with hepatocellular carcinoma: A prospective validation. Hepatology 2 Jul;62(1):158-65.  Epub 2015 Apr 22

 

P. Trivedi, W. Lammers, H. van Buuren, A.Parés, A. Floreani, H. Janssen, P. Invernizzi, P Battezzati, C. Ponsioen, C. Corpechot, R. Poupon, M. Mayo, A. Burroughs, F. Nevens, A. Mason, K. Kowdley, A. Leo,L. Caballeria, K. Lindor, B. Hansen, G. Hirschfield, on behalf of the Global PBC Study group. (2015) Stratification of Hepatocellular Carcinoma Risk in Primary Biliary Cirrhosis: A Multi-Center International Study. Gut DOI:10.1136/gutjnl-2014-308351

 

Tsang, R.S., L. Hoang, G.J. Tyrrell, G. Horsman, J. Wylie, F. Jamieson, B. Lefebvre and M. Taha. (2015) Genetic and antigenic characterization of Canadian invasive Neisseria meningitidis serogroup C (MenC) case isolates in the post MenC-conjugate vaccine era, 2009-2013. Journal of Medical Microbiology. 64(Pt2):174-179.  PMID:25587078.

 

C-Y Tseg and J.A. Tuszynski (2015) A Unified Approach to Drug Discovery, Drug Discovery Today,(accepted June 5, 2015) IF=6.422

 

C-Y Tseg and J.A. Tuszynski (2015) Entropic analysis reveals a connection between the recurrence of cancer and chemotherapy, Saudi Journal of Biological Sciences,  Volume 22, Issue 6, November 2015, Pages 674–678, IF=1.274

 

Unterweger, D., Kostiuk, B., Oetjengerdes, R., Wilton, A., Diaz, L., and Pukatzki, S.: (2015) Chimeric adaptor proteins translocate diverse type VI secretion system effectors in Vibrio cholerae. EMBO Journal: 34(16): 2198-2210.

 

Viricel C, Ahmed M, Barakat K (2015) Human PD-1 binds differently to its human ligands: A comprehensive modeling study. J Mol Graph Model 57C: 131-142.

Wang Y, Buggia-Prévot V, Zavorka ME, Bleackley RC, MacDonald RG, Thinakaran G, Kar S. (2015) Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability. Mol Cell Biol. 2 Jul;35(14):2368-84.

 

W. Wang, J. Jovel, B. Halloran, E. Wine, J. Patterson, G. Ford, S. O’Keefe, Bo Meng, D. Song, Y. Zhang, Z. Tian, S. Wasilenko, M. Rahbari, S. Reza, T. Mitchell, T. Jordan, E. Carpenter, K. Madsen, R. Fedorak, L. Dieleman, G. Wong. A. Mason (2015) Metagenomic analyses of microbiome in colon tissue from subjects with inflammatory bowel diseases reveals interplay of viruses and bacteria. Inflammatory Bowel Disease 21;1419-27.

 

W. Wang, S. Indik, G.K. Wong, A.L. Mason. (2015) Editorial: betaretrovirus in biliary epithelia of patients with autoimmune and cryptogenic liver disease – authors’ reply. Aliment. Pharmacol. Ther. 41: 491. PMID: 25631652. DOI: 10.1111/apt.13082

 

W. Wang, S. Indik, S.T. Wasilenko, A. Faschinger, E.J. Carpenter, Z. Tian, Y. Zhang, G.K. Wong, A.L. Mason. (2015) Frequent proviral integration of the human betaretrovirus in biliary epithelium of patients with autoimmune and idiopathic liver disease. Aliment. Pharmacol. Ther. PMID: 25521721. DOI: 10.1111/apt.13054;[Epub ahead of print]

 

Waye, A., A. Chuck, P. Jacobs, G.J. Tyrrell, J.D. Kellner, V. Remple. (2015)  Prevnar 7 childhood immunization program in pneumococcal incidence and resulting impact on health care costs in Alberta (2003-2008). Drugs – Real World Outcomes.  2(2):153-161.

 

Weber, B.S., Ly, P.M., Irwin, J.N., Pukatzki, S., Feldman, M.F.: (2015) A multidrug resistance plasmid acts as a molecular switch for T6SS in Acinetobacter baumannii. Proceedings of the National Academy of Sciences 112: 9442-9447. 2015.

 

West, A.P., Khoury-Hanold, W., Staron, M., Tal, M.C., Pineda, C.M., Lang, S.M., Bestwick, M., Duguay, B.A., Raimundo, N., MacDuff, D.A., Kaech, S.M., Smiley, J.R., Means, R.E., Iwasaki, A,. Shadel, G.S. (2015) Mitochondrial DNA stress primes the antiviral innate immune response.  Nature 520: 553-557.

 

Wilson J, Tyrrell DL, et al.  The Fourth Canadian Symposium on Hepatitis C:  Moving Towards a National Action Plan”.   Canadian Journal of Gastroenterology & Hepatology.  October 2015  ACCEPTED

 

Wu C, Molavi O, Zhang H, Gupta N, Alshareef A, Bone K, Gopal K, Wu F, Lewis J, Douglas D, Kneteman N, Lai R. (2015) STAT1 is phosphorylated and down-regulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large cell lymphoma. Blood. July 16;126(3):336-45.  Epub 2015 Apr 28.

 

Yang Y, Moore MJ, Brockington SF, Soltis DE, Wong GK, Carpenter EJ, Zhang Y, Chen L, Yan Z, Xie Y, Sage RF, Covshoff S, Hibberd JM, Nelson MN, Smith SA. (2015) Dissecting Molecular Evolution in the Highly Diverse Plant Clade Caryophyllales Using Transcriptome Sequencing. Mol Biol Evol. 2015 Aug;32(8):2001-14. doi: 10.1093/molbev/msv081. Epub 2015 Apr 2.

 

Yeh LC, Banerjee A, Prasad V, Tuszynski JA, Weis A, Bakos T, Yeh IT, Ludueña RF and Lee JC (2015) Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells over-expressing the βIII isotype of tubulin, New Investigational Drugs (accepted December 18, 2015), IF=2.919

 

You, J., Hou, S., Malik-Soni, N., Xu, Z., Kumar, A., Rachubinski, R.A., Frappier, L., and Hobman, T.C. (2015) Flavivirus infection impairs peroxisome biogenesis and early anti-viral signaling. J. Virol 89: 12349-61. doi: 10.1128/JVI.01365-15.
This article was selected by the editors for inclusion in “Spotlight,” a feature in the Journal that highlights research articles of significant interest from the current issue.

 

G. Zhang, D. Sharon, J. Jovel, L. Liu, E. Wine, N. Tahbaz, S. Indik, A. Mason (2015) Pericentriolar targeting of the Gag protein of mouse mammary tumor virus. PLoS One June 29 DOI: 10.1371/journal.pone.0131515

 

Zhuo R, Hasing ME; Team of Molecular Diagnostics, Pang XL  (2015)  A Single Nucleotide Polymorphism at the TaqMan Probe-Binding Site Impedes Real-Time Reverse Transcription-PCR-Based Detection of Norovirus GII.4 Sydney. J Clin Microbiol. Oct;53(10):3353-4.
2014

Adachi D, Tang JW, Lundeberg R, Tipples G, Charlton CL, Drews SJ. (2014) Comparison of the IMDx influenza A virus, influenza B virus, and respiratory syncytial virus A/B assay on the m2000 platform with real-time reverse transcriptase PCR assays. J Clin Microbiol. 2014 Dec;52(12):4441-2. doi: 10.1128/JCM.02565-14. Epub 2014 Oct 1.

 

Adachi D, Benedet M, Tang JW, Taylor GD. (2014) Comparative evaluation of Roche’s COBAS Ampliprep/COBAS TaqMan HIV-1 Test v2.0 and Abbott’s RealTime m2000sp/rt HIV-1 assay on PPTs and EDTA samples. J Clin Virol. May;60(1):78-9. doi: 10.1016/j.jcv.2014.01.019. Epub 2014 Feb 4. No abstract available.

 

Adokoh CK, Quan S, Hitt M, Darkwa J, Kumar P, Narain R. (2014) Synthesis and Evaluation of Glycopolymeric Decorated Gold Nanoparticles Functionalized with Gold-Triphenyl Phosphine as Anti-Cancer Agents. Biomacromolecules 15(10): 3802-10.

 

Agrawal A, Samrat SK, Kumar R, Tyrrell DLJ, and Agrawal B.  (2014) Co-Incubation with core proteins of HBV and HCV leads to modulation of human Dendritic Cells.  Viral Immunol. 2014 Oct;27(8):412-7. doi: 10.1089/vim.2014.0056. Epub 2014 Aug 22.

 

Anggakusuma, Colpitts, CC, LM Schang, Rachmawati, H, Frentzen, A, Pfaender, S, Behrendt, P, Brown, RJP, Bankwitz, D, Steinmann, J Ott, M, Meuleman, P, Pietschmann, T, Steinmann, E (2014) Turmeric curcumin inhibits entry of all hepatitis c virus genotypes into human liver cells. Gut 63(7):1137-1149.

 

Anwar-Mohamed A, Barakat KH, Bhat R, Noskov SY, Tyrrell DL, Tuszynski JA, Houghton M. (2014) A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity. Toxicol Lett. 2014 Nov 4;230(3):382-92. doi: 10.1016/j.toxlet.2014.08.007. Epub 2014 Aug 13.

 

Asrani SK, Wiesner R, Trotter JF, Klintmalm G, Katz E, Maller E, Roberts J, Kneteman N, Teperman L, Fung JJ, Millis JM. De novo sirolimus and reducted dose tacrolimus versus standard dose tacrolimus after liver transplantation: the 2000-2003 phase II prospective randomized trial.  AJT 2014 Feb;14(2):356-66,[ Epub ahead of print].

 

Awate S, Wilson HL, Singh B, Babiuk LA, Mutwiri G. (2014) The adjuvant PCEP induces recruitment of myeloid and lymphoid cells at the injection site and draining lymph node. Vaccine. 32(21):2420-7. doi: 10.1016/j.vaccine.2014.03.014. Epub 2014 Mar 21.

 

Axel, A, Kin T, O’Gorman D, Bigam D, Knetman N, Peters , Shapiro James. Impact of Adverse Pancreatic Injury at Surgical Procurement Upon Islet Isolation Outcome. Transplant International. 30 June 2014 Volume 27, Issue 11, November 2014, Pages: 1135–1142 [ Epub ahead of print].

 

Barakat K, Houghton M, Tyrrell DLJ,  Tuszynski J.    (2014) Rational Drug Design:  One Target, Many Paths to IT.  Int. J Computational Models & Algorithms in Med.  DOI: 10.4018/ijcmam.2014010104

 

Barakat KH, Anwar-Mohamed A, Tuszynski JA, Robins MJ, Tyrrell DL, Houghton M. (2014) A Refined Model of the HCV NS5A Protein Bound to Daclatasvir Explains Drug-Resistant Mutations and Activity against Divergent Genotypes. J Chem Inf Model. 2014 Apr 14. [Epub ahead of print]

 

Benesch, M.G.K., Tang, X., Maeda, T., Ohhata, A., Zhao, Y.Y., Kok, B.P.C., Dewald, J., Hitt, M., Curtis, J.M., McMullen, T.P.W., and Brindley, D.N. (2014) Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice. FASEB J. 28(6): 2655-66.

 

T. Bennett, S.F. Brockington, C. Rothfels, S.W. Graham, D. Stevenson, T. Kutchan, M. Rolf, P. Thomas, G.K. Wong, O. Leyser, et al. (2014) Paralogous radiations of PIN proteins with multiple origins of noncanonical PIN structure. Mol. Biol. Evol. 31: 2042-2060. PMID: 24758777. DOI: 10.1093/molbev/msu147
Burles K, van Buuren N, Barry M. (2014) Ectromelia virus encodes a family of Ankyrin/F-box proteins that regulate NFκB. Virology. 2014 Nov;468-470:351-62. doi: 10.1016/j.virol.2014.08.030. Epub 2014 Sep 18.

 

Bareiss B, Barry M. (2014) Fowlpox virus encodes two p28-like ubiquitin ligases that are expressed early and late during infection. Virology. 2014 Aug;462-463:60-70. doi: 10.1016/j.virol.2014.05.018. Epub 2014 Jun 17.

 

Bleackley RC. (2014) Cloning CTL-Specific Genes (And Now for Something Completely Differential). Front Immunol. 2014 Oct 14;5:509. doi: 10.3389/fimmu.2014.00509. eCollection 2014. Review. No abstract available.

 

Burles K, Irwin CR, Burton RL, Schriewer J, Evans DH, Buller RM, Barry M. (2014) Initial characterization of vaccinia virus B4 suggests a role in virus spread. Virology. 2014 May;456-457:108-20. doi: 10.1016/j.virol.2014.03.019. Epub 2014 Apr 4.

 

Campbell S, Thibault J, Mehta N, Colman PM, Barry M, Kvansakul M. (2014) Structural insight into BH3 domain binding of vaccinia virus antiapoptotic F1L. J Virol. 2014 Aug;88(15):8667-77. doi: 10.1128/JVI.01092-14. Epub 2014 May 21.

 

Cardoso FS, Karvellas CJ, Kneteman NM, Meeberg G, Fidalgo P, Bagshaw SM. Respiratory rate at intensive care unit discharge after liver transplant is an independent risk factor for intensive care unit readmission within the same hospital stay: A nested case-control study. J. Crit Care. 24 April 2014 [Epub ahead of print]

 

P.A. Christin, M. Arakaki, C.P. Osborne, A. Bräutigam, R.F. Sage, J.M. Hibberd, S. Kelly, S. Covshoff, G.K. Wong, L. Hancock, et al. (2014) Shared origins of a key enzyme during the evolution of C4 and CAM metabolism. J. Exp. Bot. 65: 3609-3621. PMID: 24638902. DOI: 10.1093/jxb/eru087

 

Churchill CD, Klobukowski M, Tuszynski JA. (2014) The Unique Binding Mode of Laulimalide to Two Tubulin Protofilaments. Chem Biol Drug Des. 2014 Nov 6. doi: 10.1111/cbdd.12475. [Epub ahead of print]

 

Congly SE, Doucette KE, Coffin CS. (2014) Outcomes and management of viral hepatitis and human immunodeficiency virus co-infection in liver transplantation. World J Gastroenterol. 2014 Jan 14;20(2):414-24. doi: 10.3748/wjg.v20.i2.414. Review.

 

Colombatto P, Brunetto MR, Maina AM, Romagnoli V, Almasio P, Rumi MG, Ascione A, Pinzello G, Mondelli M, Muratori L, Rappuoli R, Rosa, D, Houghton M, Abrignani S, Bonino F. (2014) HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFNα2a and ribavirin: a randomized controlled trial. J. Viral Hepatitis. 21:458-65.

 

Colpitts, CC, and Schang, LM (2014) A small molecule inhibits attachment to heparan sulfate- or sialic acid-containing glycans. Journal of Virology 88 (14): 7806-7817.

 

Conroy AL, Gélvez M, Hawkes M, Rajwans N, Liles WC, Villar-Centeno LA, Kain KC. (2014)  Host biomarkers distinguish dengue from leptospirosis in Colombia: a case-control study. BMC Infect Dis. Jan 20;14(1):35. doi: 10.1186/1471-2334-14-35.

 

Cooper C, Shafran S, Greenbloom S, Enns R, Farley J, Hilzenrat N, Williams K, Elkashab M, Abadir N, Neuman M. (2014) Single-dose infliximab in hepatitis C genotype 1 treatment-naive patients with high serum tumour necrosis factor-alpha does not influence the efficacy of pegylated interferon alpha-2b/ribavirin therapy. Can J Gastroenterol. Jan;28(1):35-40. Epub 2013 Nov 8.

Cooper T, Biron B, Fast D, Tam R, Carey T, Shmulevitz, M, Seikaly H* (2014) Oncolytic activity of reovirus in HPV positive and negative head and neck squamous cell carcinoma. J. Otolaryngology – Head and Neck Surgery, In

 

Craddock TJ, Friesen D, Mane J, Hameroff S, Tuszynski JA. (2014) The feasibility of coherent energy transfer in microtubules. J R Soc Interface. 2014 Nov 6;11(100):20140677. doi: 10.1098/rsif.2014.0677.

 

Dang CC, Le VS, Gascuel O, Hazes B, Le QS. (2014) FastMG: a simple, fast, and accurate maximum likelihood procedure to estimate amino acid replacement rate matrices from large data sets. BMC Bioinformatics. 2014 Oct 24;15:341. doi: 10.1186/1471-2105-15-341.

 

Dauber B, Saffran HA, Smiley JR. (2014) The herpes simplex virus 1 virion host shutoff protein enhances translation of viral late mRNAs by preventing mRNA overload. J Virol.  Sep 1;88(17):9624-32. doi: 10.1128/JVI.01350-14. Epub 2014 Jun 11.

 

Chelsea L. Davidson, Lisa E. Cameron, and Deborah N. Burshtyn (2014) The AP-1 transcription factor JunD activates the leukocyte immunoglobulin-like receptor 1 distal promoter Int. Immunol. 26 (1): 21-33 first published online September 13, 2013 doi:10.1093/intimm/dxt038

 

Demczuk, W., T. Lynch, I. Martin, G. Van Domselaar, M. Graham, A. Bharat, V. Allen, L. Hoang, B. Lefebvre, G.J. Tyrrell, G. Horsman, D. Haldane, R. Garceau, J. Wylie, T. Wong, and M. Mulvey (2014) Whole-genome phylogenetic heterogeneity of Neisseria gonorrhoeae with decreased cephalosporin susceptibility collected in Canada between 1989 and 2013. Journal of Clincial Microbiology. IN PRESS.

 

Deriu MA, Grasso G, Licandro G, Danani A, Gallo D, Tuszynski JA, Morbiducci U. (2014) Investigation of the Josephin Domain protein-protein interaction by molecular dynamics. PLoS One. 2014 Sep 30;9(9):e108677. doi: 10.1371/journal.pone.0108677. eCollection 2014.

 

Dore G, Lawitz E, Hézode C, Shafran SD, Ramji A, Tatum HA, Taliani G, Tran A, Brunetto MR, Zaltron S, Strasser SI, Weis N, Ghesquiere W, Lee SS, Larrey D, Pol S, Harley H, George J, Fung S, de Lédinghen V, Hagens P, McPhee F, Hernandez D, Cohen D, Cooney E, Noviello S, Hughes EA. (2014) Daclatasvir and peginterferon/ribavirin has higher efficacy with shorter treatment duration for hepatitis C virus genotype 2 or 3 infection. Gastroenterology Oct 10. [Epub ahead of print].

 

Duguay BA, Saffran HA, Ponomarev A, Duley SA, Eaton HE, Smiley JR. (2014) Elimination of mitochondrial DNA is not required for herpes simplex virus 1 replication. J Virol. Mar;88(5):2967-76. doi: 10.1128/JVI.03129-13. Epub 2013 Dec 26.

 

Eaton HE, Saffran HA, Wu FW, Quach K, Smiley JR. (2014) Herpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activity. J Virol. Jul;88(13):7379-88. doi: 10.1128/JVI.00712-14. Epub 2014 Apr 16.

 

Egli A, Santer DM, O’Shea D, Barakat K, Syedbasha M, Vollmer M, Baluch A, Bhat R, Groenendyk J, Joyce MA, Lisboa LF, Thomas BS, Battegay M, Khanna N, Mueller T, Tyrrell DL, Houghton M, Humar A, Kumar D. (2014) IL-28B is a Key Regulator of B- and T-Cell Vaccine Responses against Influenza. PLoS Pathog. 2014 Dec 11;10(12):  e1004556. doi: 10.1371/journal.ppat.1004556. eCollection 2014 Dec.

 

Egli A, Santer D, Barakat K, Zand M, Levin A, Vollmer M, Weisser M, Khanna N, Kumar D, Tyrrell L, Houghton M, Battegay M, O’Shea D. (2014) Vaccine adjuvants–understanding molecular mechanisms to improve vaccines. Swiss Med Wkly. 2014 May 20;144:w13940. doi: 10.4414/smw.2014.13940. eCollection 2014.

 

Egli A, Levin A, Santer DM, Joyce M, O’Shea D, Thomas BS, Lisboa LF, Barakat K, Bhat R, Fischer KP, Houghton M, Tyrrell DL, Kumar D, Humar A. (2014) Immunomodulatory Function of Interleukin 28B during primary infection with cytomegalovirus. J Infect Dis. 2014 Sep 1;210(5):717-27. doi: 10.1093/infdis/jiu144. Epub 2014 Mar 11.

 

Egli A, Santer DM, O’Shea D, Tyrrell DL, and Houghton M.  (2014) The impact of the interferon lambda family on the innate and adaptive immune response to viral infections.  Emerging Microbes and Infections.  (2014) 3, e51; doi:10.1038/emi.2014.51   Published online 16 July 2014

 

Elahi S, Van Kessel J, Kiros TG, Strom S, Hayakawa Y, Hyodo M, Babiuk LA, Gerdts V. (2014) c-di-GMP enhances protective innate immunity in a murine model of pertussis. PLoS One. 9(10):e109778. doi: 10.1371/journal.pone.0109778. eCollection 2014.

 

Evans DH, Fox MP, Maskew M, McNamara L, MacPhail P, Mathews C, Sanne I. (2014) CD4 criteria improves the sensitivity of a clinical algorithm developed to identify viral failure in HIV-positive patients on antiretroviral therapy. J Int AIDS Soc. 2014 Sep 15;17:19139. doi: 10.7448/IAS.17.1.19139. eCollection 2014.

 

Fathima S, Ferrato C, Lee BE, Simmonds K, Yan L, Mukhi SN, Li V, Chui L, Drews SJ. (2014) Bordetella pertussis in sporadic and outbreak settings in Alberta, Canada, July 2004 – December 2012. BMC Infect Dis. 2014;14:48. [Epub ahead of print] PubMed PMID: 24476570

 

Finnen RL, Hay TJ, Dauber B, Smiley JR, Banfield BW. (2014) The herpes simplex virus 2 virion-associated ribonuclease vhs interferes with stress granule formation. J Virol.  Nov;88(21):12727-39. doi: 10.1128/JVI.01554-14. Epub 2014 Aug 20.

 

S.K. Floyd, J.G. Ryan, S.J. Conway, E. Brenner, K.P. Burris, J.N. Burris, T. Chen, P.P. Edger, S.W. Graham, J.H. Leebens-Mack, J,C. Pires, CJ Rothfels , EM Sigel , DW Stevenson , C Neal Stewart Jr, GK Wong , JL Bowman. (2014). Origin of a novel regulatory module by duplication and degeneration of an ancient plant transcription factor. Mol. Phylogenet. Evol. 81: 159-173. PMID: 25263420. DOI: 10.1016/j.ympev.2014.06.017

 

Forbrich, A., Paproski, R., Hitt, M., and Zemp, R. (2014). Comparing efficiency of micro-RNA and mRNA biomarker liberation with microbubble-enhanced ultrasound exposure. Ultrasound Med Biol. 40(9): 2207-16.

 

Foster JR, Lund G, Sapelnikova S, Tyrrell DLJ, Kneteman NM. (2014) Chimeric rodents with humanized livers:  bridging the preclinical/clinical trial gap in ADME/toxicity studies.  Xenobiotica:  the fate of foreign compounds in biological systems.  2014 Jan:44(2):109-22. Doi:10.3109/00498254.2013.867553

 

Fraser, B., Maranchuk, R., and Foley, E. (2014) Identification of Ubiquitin Pathway Modifiers of the TNF NF-κB Axis. Frontiers in Immunology. 2014 5:322. doi: 10.3389/fimmu.2014.00322. Research funded by CIHR/LKS IoV.

 

Guntermann, S., Hazes, B., and Foley, E. (2014) Caspase Activation and Activity in the Drosophila Immune Deficiency Pathway. Under revision for the Journal of Innate Immunity. Submitted Feb 2014. Research funded by NSERC.

 

Hasing ME, Hazes B, Lee BE, Preiksaitis JK, Pang XL. (2014) Detection and analysis of recombination in GII.4 norovirus strains causing gastroenteritis outbreaks in Alberta. Infect Genet Evol. 2014 Oct;27:181-92. doi: 10.1016/j.meegid.2014.07.016. Epub 2014 Jul 24.

 

Hawkes M, Conroy AC, Opoka R, Namasopo S, Liles WC, John C, Kain, K. (2014) Performance of point-of-care diagnostics for glucose, lactate, and hemoglobin in the management of severe malaria in a resource-constrained hospital in Uganda. Am J Trop Med Hyg. 90:605-608; Published online March 3, 2014, doi:10.4269/ajtmh.13-0689

 

Hawkes M, Conroy AL, Opoka RO, Namasopo S, Liles WC, John CC, Kain KC. (2014) Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children. Malar J. Feb 1;13(1):43.

 

Hazes B. (2014) CDSbank: taxonomy-aware extraction, selection, renaming and formatting of protein-coding DNA or amino acid sequences. BMC Bioinformatics. 2014 Feb 28;15:61. doi: 10.1186/1471-2105-15-61.

 

Hendry RG, Bilawchuk LM, Marchant DJ. (2014) Targeting matrix metalloproteinase activity and expression for the treatment of viral myocarditis. J Cardiovasc Transl Res. Mar;7(2):212-25. doi: 10.1007/s12265-013-9528-2. Epub 2014 Jan 1. Review.

 

Hézode C, Hirschfield GM, Ghesquiere W, Sievert W, Rodriguez-Torres M, Shafran SD, Thuluvath PJ, Tatum HA, Waked I, Esmat G, Lawitz EJ, Rustgi VK, Pol S, Wels N, Pockros PJ, Bourliere M, Serfaty L, Vierling JM, Fried MW, Weiland O, Brunetto MR, Everson GT, Zeuzem S, Kwo PY, Sulkowski M, Bräu N, Hernandez D, McPhee F, Wind-Rotolo M, Liu Z, Noviello S, Hughes EA, Yin PD, Schnittman S. (2014) Daclatasvir plus peginterferon alfa and ribavirin for treatment-naïve chronic hepatitis C genotype 1 or 4: a randomized study. Gut 2014. Jul 30. [Epub ahead of print].

 

Hirschfield GM, Mason A, Luketic V, Lindor K, Gordon S, Mayo M, Kowdley KV, Vincent C, Bodhenheimer HC Jr, Parés A, Trauner M, Marschall HU, Adorini L, Sciacca C, Beecher-Jones T, Castelloe E, Böhm O, Shapiro D. (2014) Efficacy of Obeticholic Acid in Patients with Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid. Gastroenterology. Dec 11. pii: S0016-5085(14)01530-3. doi: 10.1053/j.gastro.2014.12.005. [Epub ahead of print]

 

Hobman TC, McCormick C. (2014) Editorial overview: viruses and RNA interference. Curr Opin Virol. 2014 Aug;7:vii-x. doi: 10.1016/j.coviro.2014.07.001. Epub 2014 Jul 17. No abstract available.

 

Daniel R Hochbaum, Yongxin Zhao, Samouil L Farhi,  Nathan Klapoetke,  Christopher A Werley,  Vikrant Kapoor,  Peng Zou,  Joel M Kralj,  Dougal Maclaurin,  Niklas Smedemark-Margulies,  Jessica L Saulnier,  Gabriella L Boulting,  Christoph Straub,  Yong Ku Cho,  Michael Melkonian,  Gane Ka-Shu Wong,  D Jed Harrison,  Venkatesh N Murthy,  Bernardo L Sabatini, Edward S Boyden, Robert E Campbell &  Adam E Cohen (2014) All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins. Nat. Methods 11: 825-833. PMID: 24952910. DOI: 10.1038/nmeth.3000

 

Houghton M. (2014) Hepatitis C: The next 25 years. Antiviral Res. 110:77-78.

 

Hsu I, Parkinson LG, Shen Y, Toro A, Brown T, Zhao H, Bleackley RC, Granville DJ. (2014) Serpina3n accelerates tissue repair in a diabetic mouse model of delayed wound healing. Cell Death Dis. 2014 Oct 9;5:e1458. doi: 10.1038/cddis.2014.423.

 

Irwin CR, Favis NA, Agopsowicz KC, Hitt MM, Evans DH. (2014) Myxoma virus oncolytic efficiency can be enhanced through chemical or genetic disruption of the actin cytoskeleton. PLoS One. 2013 Dec 31;8(12):e84134. doi: 10.1371/journal.pone.0084134. eCollection 2013.

 

Islam A, Schulz S, Afroz S, Babiuk LA, van Drunen Littel-van den Hurk S. (2014) Interaction of VP8 with mRNAs of bovine herpesvirus-1. Virus Res. 197C:116-126. doi: 10.1016/j.virusres.2014.12.017. [Epub ahead of print]

 

Karvellas C, Desousa C, Bagshaw , Abraldes J, Kneteman N, Meeberg G, Fidalgo .  Comorbidities have alimited impact on post-transplant survival in carefully selected cirrhotic patients: a population-based cohort study. Submitted  Annals of Hepatology, 11 November 2014.

 

Kashkoush S, El Moghazy W, Kawahara T, Gala-Lopez B, Toso C, Kneteman N. Three-dimensional tumor volume and serum alphafetoprotein are predictiors of Hepatocellular Carcinoma recurrence after liver transplantation: Refinde selection criteria. Cinical Transplant 2014 28:728-726.  April 08, 2014

 

Kerage D, Brindley DN and Hemmings DG. “Novel insights into the regulation of vascular tone by sphingosine 1-phosphate,” Placenta Feb 17: S86-S92, 2014 (IF = 3.289, ranked 6 out of 30 Reproductive Biology journals)

 

Knoll GA, Humar A, Fergusson D, Johnston O, House AA, Kim SJ, Ramsay T, Chassé M, Pang X, Zaltzman J, Cockfield S, Cantarovich M, Karpinski M, Lebel L, Gill JS. (2014) Levofloxacin for BK Virus Prophylaxis Following Kidney Transplantation: A Randomized Clinical Trial. JAMA. Nov 15. doi: 10.1001/jama.2014.14721. [Epub ahead of print]

 

N.C. Klapoetke, Y. Murata, S.S. Kim, S.R. Pulver, A. Birdsey-Benson, Y.K. Cho, T.K. Morimoto, A.S. Chuong, E.J. Carpenter, Z. Tian, … G.K. Wong, E.S. Boyden. (2014) Independent optical excitation of distinct neural populations. Nat. Methods 11: 338-346. PMID: 24509633. DOI: 10.1038/nmeth.2836

 

Kumar P, Ayalew LE, Godson DL, Gaba A, Babiuk LA, Tikoo SK. (2014) Mucosal immunization of calves with recombinant bovine adenovirus-3 coexpressing truncated form of bovine herpesvirus-1 gD and bovine IL-6. Vaccine. 32(26):3300-6. doi: 10.1016/j.vaccine.2014.03.073. Epub 2014 Apr 13.

 

Lai FY, Dover DC, Lee B, Fonseca K, Solomon N, Plitt SS, Jaipaul J, Tipples GA, Charlton CL. (2014) Determining rubella immunity in pregnant Alberta women 2009-2012. i. Epub  Dec 19.

 

Lammers WJ, van Buuren HR, Hirschfield GM, Janssen HL, Invernizzi P, Mason AL, Ponsioen CY, Floreani A, Corpechot C, Mayo MJ, Battezzati PM, Parés A, Nevens F, Burroughs AK, Kowdley KV, Trivedi PJ, Kumagi T, Cheung A, Lleo A, Imam MH, Boonstra K, Cazzagon N, Franceschet I, Poupon R, Caballeria L, Pieri G, Kanwar PS, Lindor KD, Hansen BE; Global PBC Study Group. (2014) Levels of Alkaline Phosphatase and Bilirubin Are Surrogate End Points of Outcomes of Patients With Primary Biliary Cirrhosis: An International Follow-up Study. Gastroenterology. Dec;147(6):1338-1349.e5. doi: 10.1053/j.gastro.2014.08.029. Epub 2014 Aug 23.

 

Landi A, Weismuller TJ, Lankisch TO, Santer DM, Tyrrell DL, Manns MP, Houghton M. (2014) Differential serum levels of eosinophilic eotaxins in primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis. J. Interferon Cytokine Res. March 2014: 204-214.

 

Law, D., J. Zhou, S. Deng, L Hoang, G.J. Tyrrell, G. Horsman, J. Wylie and R.S. Tsang. (2014) Determination of serotyping antigens, clonal analysis and genetic characterization of the 4CMenB vaccine antigen genes in invasive Neisseria meningitidis from western Canada, 2009 to 2013. J of Medical Microbiology. August 27, 2014. EPUB. PMID:25165123

 

Lee HK, Tang JW, Loh TP, Kong DH, Lau YW, Yap HK, Koay ES. (2014) Emergence of G186D mutation in the presence of R292K mutation in an immunocompromised child infected with influenza A/H3N2 virus, treated with oseltamivir. J Clin Microbiol. 2014 May;52(5):1749-50. doi: 10.1128/JCM.00538-14. Epub 2014 Mar 5.

 

Lee CK, Tang JW, Chiu L, Loh TP, Olszyna D, Chew N, Archuleta S, Koay ES. (2014) Epidemiology of GB virus type C among patients infected with HIV in Singapore. J Med Virol. May;86(5):737-44. doi: 10.1002/jmv.23893. Epub 2014 Jan 31.

 

Lee BE, Pang XL. (2014) One more step toward understanding the immune response to norovirus. J Infect Dis. 2014 Dec 1;210(11):1691-2

 

Levin A, Neufeldt CJ, Pang D, Wilson K, Loewen-Dobler D, Joyce MA, Wozniak RW, Tyrrell DLJ. (2014)  Functional Characterization of Nuclear Localization and Export Signals in Hepatitis C Virus Proteins and Their Role in the Membranous Web. PLoS One. 2014 Dec 8;9(12):e114629. doi: 10.1371/journal.pone.0114629. eCollection 2014

 

F.W. Li, J.C. Villarreal, S. Kelly, C.J. Rothfels, M. Melkonian, E. Frangedakis, M. Ruhsam, E.M. Sigel, J.P. Der, J. Pittermann, … G.K. Wong, S. Mathews, K.M. Pryer. (2014) Horizontal transfer of an adaptive chimeric photoreceptor from bryophytes to ferns. Proc. Natl. Acad. Sci. USA 111: 6672-6677. PMID: 24733898. DOI: 10.1073/pnas.1319929111

 

Lin LT, Chung CY, Hsu WC, Chang SP, Hung TP, Shields J, Russell RS, Lin CC, Li CF, Yen MH, Tyrrell DLJ, Lin CC, Richardson C.   (2014) Saikosaponin b2 is a Naturally Occurring Terpenoid That Efficiently Inhibits Hepatitis C Virus Entry.  Journal of Hepatology.  doi:10.1016/j.jhep.2014.10.040  November 2014

 

Lin Z, Farooqui A, Li G, Wong GK, Mason AL, Banner D, Kelvin AA, Kelvin DJ, León AJ. (2014) Next-generation sequencing and bioinformatic approaches to detect and analyze influenza virus in ferrets. J Infect Dev Ctries. Apr 15;8(4):498-509. doi: 10.3855/jidc.3749.

 

Ma, B. Craveiro Salvado, C. M. and Kane, K.P. (2014) The activating Ly49W and inhibitory Ly49G NK cell receptors display similar affinities for identical MHC class I ligands. Immunogen. 66:467-477.

 

Mackenzie-Dyck S, Kovacs-Nolan J, Snider M, Babiuk LA, van Drunen Littel-van den Hurk S. (2014) Inclusion of the bovine neutrophil beta-defensin 3 with glycoprotein D of bovine herpesvirus 1 in a DNA vaccine modulates immune responses of mice and cattle. Clin Vaccine Immunol. 2014 Apr;21(4):463-77. doi: 10.1128/CVI.00696-13. Epub 2014 Jan 22.

 

MacParland SA, Bilodeau M, Grebely J, Bruneau J, Cooper C, Klein M, Sagan S, Choucha N, Balfour L, Bialystok F, Krajden M, Raven J, Roberts E, Russell R, Houghton M, Tyrrell DL, Feld JJ; National CIHR Research Training Program in Hepatitis C. (2014) The 3rd Canadian Symposium on Hepatitis C Virus: Expanding care in the interferon-free era. Can. J. Gastroenterol. Hepatol. 28:481-7.

 

Maghera A, Kahlke P, Lau A, Zeng Y, Hoskins C, Corbett T, Manca D, Lacaze-Masmonteil T, Hemmings DG and Mandhane P. (2014) You are how you recruit: a cohort and randomized controlled trial of recruitment strategies,” BMC Medical Research Methodology, accepted

 

V.H. Maia, M.A. Gitzendanner, P.S. Soltis, G.K. Wong, D.E. Soltis. (2014) Angiosperm phylogeny based on 18S/26S rDNA sequence data: Constructing a large data set using next-generation sequence data. Int. J. Plant Sci. 175: 613-650. PMID: unavailable. DOI: 10.1086/676675

 

Marchant DJ, Bilawchuk L, Nish G, Hegele RG. (2014) Virus-induced signaling influences endosome trafficking, virus entry, and replication. Methods Enzymol. 2014;534:65-76. doi: 10.1016/B978-0-12-397926-1.00004-4.

 

David J Marchant, Caroline L Bellac, Theo J Moraes, Samuel J Wadsworth, Antoine Dufour, Georgina S Butler, Leanne M Bilawchuk, Reid G Hendry, A Gordon Robertson, Caroline T Cheung, Julie Ng, Lisa Ang, Zongshu Luo, Karl Heilbron, Michael J Norris, Wenming Duan, Taylor Bucyk, Andrei Karpov, Laurent Devel, Dimitris Georgiadis, Richard G Hegele, Honglin Luo, David J Granville, Vincent Dive, Bruce M McManus & Christopher M Overall. (2014) A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity. Nature Medicine May; 20(5); pp493 – 502; doi:10.1038/nm.3508

 

N. Matasci, L.H. Hung, Z. Yan, E.J. Carpenter, N.J. Wickett, S. Mirarab, N. Nguyen, T. Warnow, S. Ayyampalayam, M. Barker, … J. Leebens-Mack, G.K. Wong. (2014) Data access for the 1,000 Plants (1KP) project. GigaScience 3: 17. PMID: temporarily missing. DOI: 10.1186/2047-217X-3-17

 

Miranzo-Navarro D, Magor KE. (2014) Activation of duck RIG-I by TRIM25 is independent of anchored ubiquitin. PLoS One. 2014 Jan 23;9(1):e86968. doi: 10.1371/journal.pone.0086968. eCollection 2014.

 

Mohamed A, Teicher C, Haefliger S, Shmulevitz M. (2014) Switching niches: reduced virion-associated σ1 fibers on oncolytic reovirus variants promotes adaptation towards tumorigenic cells. Under Revisions for J Virol, October

 

Montano-Loza A, Purdy DA, Meza-Junco J, Bain V, Burak KW, Wong W, Ma M, Kneteman N, Liu D, Owen R. Radioembolization with YTTRIUM-90 for advanced hepatocellular carcinoma: A Canadian experience. Liver International. Submitted August 2013.

 

Montano-Loza A, Mang Ma, Beaumont C, Esfandiari N, Sawyer M, Kneteman NM. Severe muscle depletion predicts postoperative length of stay but is not associated with survival after liver transplantation. Liver Transplantation 2014 June 20: Volume 20, Issue 6, June 2014, Pages: 640–648 [Epub ahead of print]

 

Morard I, Gasche Y, Kneteman M, Toso C, Mentha A, MeebergG, Mentha G, Kneteman N, Giorstra E. (2014) Identifying risk factors for central pontine and extrapontine myelinolysis after liver transplantation: a case-control study. Neurocrit Care. 20(2):287-95, [Epub ahead of print].

 

Muthuri SG, Venkatesan S, Myles PR, Leonardi-Bee J, Al Khuwaitir TS, Al Mamun A, Anovadiya AP, Azziz-Baumgartner E, Báez C, Bassetti M, Beovic B, Bertisch B, Bonmarin I, Booy R, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Denholm JT, Dominguez SR, Duarte PA, Dubnov-Raz G, Echavarria M, Fanella S, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Iglesias AL, Hoger PH, Hu X, Islam QT, Jiménez MF, Kandeel A, Keijzers G, Khalili H, Knight M, Kudo K, Kusznierz G, Kuzman I, Kwan AM, Amine IL, Langenegger E, Lankarani KB, Leo YS, Linko R, Liu P, Madanat F, Mayo-Montero E, McGeer A, Memish Z, Metan G, Mickiene A, Mikić D, Mohn KG, Moradi A, Nymadawa P, Oliva ME, Ozkan M, Parekh D, Paul M, Polack FP, Rath BA, Rodríguez AH, Sarrouf EB, Seale AC, Sertogullarindan B, Siqueira MM, Skręt-Magierło J, Stephan F, Talarek E, Tang JW, To KK, Torres A, Törün SH, Tran D, Uyeki TM, Van Zwol A, Vaudry W, Vidmar T, Yokota RT, Zarogoulidis P; PRIDE Consortium Investigators, Nguyen-Van-Tam JS. (2014) Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data. Lancet Respir Med. 2014 May;2(5):395-404. doi: 10.1016/S2213-2600(14)70041-4. Epub 2014 Mar 19. Review.

 

Pabbaraju K, R Tellier, S Wong, Y Li, N Bastien, JW Tang, SJ Drews, Y Jang, CT Davis, K Fonseca and GA Tipples. Full-genome analysis of avian influenza A(H5N1) virus from human, North America, 2013. Emerg Infect Dis 2014;20;887-891. doi: 10.3201/eid2005.140164

 

N. Pabón-Mora, G.K. Wong, B.A. Ambrose. (2014) Evolution of fruit development genes in flowering plants. Front. Plant Sci. 5: 300. PMID: 25018763. DOI: 10.3389/fpls.2014.00300

 

Pagadala NS, Perez-Pineiro R, Wishart DS, Tuszynski JA. (2014) In silico studies and fluorescence binding assays of potential anti-prion compounds reveal an important binding site for prion inhibition from PrPC to PrPSc. Eur J Med Chem. 2014 Jul 15. pii: S0223-5234(14)00652-7. doi: 10.1016/j.ejmech.2014.07.045. [Epub ahead of print]

 

Pang L, Hasing E, Preiksaitis JK, Lee B, Hazes B. (2014) Detection and analysis of recombination in GII.4 norovirus strains causing gastroenteritis outbreaks in Alberta. Infect Genet Evol 2014 Oct;27:181-92. doi: 10.1016/j.meegid.2014.07.016. Epub 2014 Jul 24.

 

Pang XL, Preiksaitis JK, and Lee BE. (2014) Enhanced enteric virus detection in sporadic gastroenteritis using a multi-target real-time PCR panel – A one-year study. J Medical Virology. 2014. 86:1594-1601

 

Paproski, R.J., Forbrich, A.E., Wachowicz, K., Hitt, M., and Zemp, R. J.  (2014) RNA Biomarker Release with Ultrasound and Phase-Change Nanodroplets. Ultrasound Med Biol. 40(8):1847-56.

 

Pearson JD, Zhang J, Wu Z, Thew KD, Rowe KJ, Bacani JT, Ingham RJ. (2014) Expression of granzyme B sensitizes ALK+ ALCL tumour cells to apoptosis-inducing drugs. Mol Cancer. 2014 Aug 29;13:199. doi: 10.1186/1476-4598-13-199.

 

Petkau, K., Parsons, D.B, Duggal, A., and Foley, E. (2014) A Deregulated Intestinal Cell Cycle Program Disrupts Tissue Homeostasis, Without Affecting Longevity in Drosophila. Journal of Biological Chemistry. 2014 289(41): 28719-29. Research funded by CIHR.

 

Pittman C, Plitt S, Birse T, Doucette K, Romanowski B, Cooper R, Houston S, Shafran S, Singh AE. (2014) Prevalence and correlates of HIV and hepatitis B virus coinfection in Northern Alberta. Can J Infect Dis Med Microbiol. 2014 Spring;25(1):e8-e13.

 

PressDar A, Tikoo S, Potter A, Babiuk LA, Townsend H, Gerdts V, Mutwiri G. (2014) CpG-ODNs induced changes in cytokine/chemokines genes expression associated with suppression of infectious bronchitis virus replication in chicken lungs. Vet Immunol Immunopathol. 160(3-4):209-17. doi: 10.1016/j.vetimm.2014.05.004. Epub 2014 May 21.

 

Ptak C, Wozniak RW. (2014) Assessing regulated nuclear transport in Saccharomyces cerevisiae. Methods Cell Biol. 2014;122:311-30. doi: 10.1016/B978-0-12-417160-2.00014-X.

 

Ptak C, Aitchison JD, Wozniak RW. (2014) The multifunctional nuclear pore complex: a platform for controlling gene expression. Curr Opin Cell Biol. 2014 Jun;28:46-53. doi: 10.1016/j.ceb.2014.02.001. Epub 2014 Mar 22. Review.

 

Qin L, Evans DH. (2014) Genome scale patterns of recombination between coinfecting vaccinia viruses. J Virol. 2014 May;88(10):5277-86. doi: 10.1128/JVI.00022-14. Epub 2014 Feb 26.

 

Robinson JL, Suresh S, Lee BE. (2014) That other EVD: Enterovirus-D68 – what’s it all about? Can J Infect Dis Med Microbiol. 2014 Nov-Dec;25(6):296-8. No abstract available.

 

Robinson JL, Meier K, Lee BE, Larke B. (2014) Could urine be useful for the diagnosis of Chlamydia trachomatis pneumonia in infancy? Diagn Microbiol Infect Dis. 2014 Jul;79(3):308-9. doi: 10.1016/j.diagmicrobio.2014.01.030. Epub 2014 Feb 20. PubMed PMID: 24768625

 

Rooney BL, Pettipas J, Grudeski E, Mykytczuk O, Pang XL, Booth TF, Hatchette TF, LeBlanc JJ. (2014) Detection of circulating norovirus genotypes: hitting a moving target. Virol J. 2014 Jul 18;11:129

 

Saberi Fathi SM, White DT, Tuszynski JA. (2014) Geometrical comparison of two protein structures using Wigner-D functions. Proteins. 2014 Oct;82(10):2756-69. doi: 10.1002/prot.24640. Epub 2014 Jul 17.

 

C. Sayou, M. Monniaux, M.H. Nanao, E. Moyroud, S.F. Brockington, E. Thévenon, H. Chahtane, N. Warthmann, M. Melkonian, Y. Zhang, G.K. Wong , D. Weigel , F. Parcy , R. Dumas . (2014) A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity. Science 343: 645-648. PMID: 24436181. DOI: 10.1126/science.1248229

 

Schang, LM (2014) Biophysical Approaches to Entry Inhibitor Antivirals with Broad-Spectrum of Action. Future Virology 9(3):283-299. Review

 

Serugendo AN, B. J. Kirenga BJ, Hawkes M, Nakiyingi L, Worodria W, Okot-Nwang M. (2014) Evaluation of asthma control using Global Initiative for Asthma criteria and the Asthma Control Test in Uganda. Int J Tuberc Lung Dis. 18(3):371–376.

 

Shafran DM, Shafran SD. (2014) Five things to know about…treating Clostridium difficile infection. CMAJ 186:531.

 

Sharon D, Chen M, Zhang G, Girgis S, Sis B, Graham D, McDougall C, Wasilenko ST, Montano-Loza A, Mason AL. (2014) Impact of combination antiretroviral therapy in the NOD.c3c4 mouse model of autoimmune biliary disease. Liver Int. Oct 10. doi: 10.1111/liv.12699. [Epub ahead of print]

 

Shott, RH, Meijer, Frost, K, Booth, SA,and Schang, LM (2014) Activation of Pro-survival CaMK4β/CREB and Pro-death MST1 Signaling at Early and Late Times during a mouse model of prion disease. Virology Journal 11:160 (20 pages).

 

Shott, RH, Appanah, C, Grenier, C, Tremblay, G, Roucou, X, and Schang, LM (2014) Development of Kinomic Analyses to Identify Dysregulated Signaling Pathways in Cells Expressing Cytoplasmic PrP. Virology Journal 11:175 (18 pages).

 

Simmonds, D.K., S. Fathima1 L. Chui, M.Lovgren, P. Shook, M. Shuel, G. J. Tyrrell, R. Tsang, S.J. Drews. (2014) Dominance of two genotypes of Bordetella pertussis during a period of increased pertussis activity in Alberta, Canada: January 2012 – August 2012. Int.Jfor Infectious Diseases. October 6, 2014. IN PRESS.

 

Singaravelu R, Russell RS, Tyrrell DLJ, Pezacki John Paul.  (2014) Hepatitis C virus and microRNAs:  miRed in a host of possibilities.  Current Opinion in Virology.  2014 April 7;7C:1-10. Doi: 10.1016/j.coviro.2014.03.004 (Epub ahead of Print)

 

Singaravelu R, Delcorde J, Lyn R, Jones D, Steenbergen R, Tyrrell DLJ, Russell R, Pezacki J. (2014)  Investigating the antiviral role of cell death-inducing DFF45-like effector B in HCV replication.  The FEBS Journal.  2014 Aug;281(16):3751-65. doi: 10.1111/febs.12901. Epub 2014 Jul 23.

 

S. Sveinsson, J. McDill, G.K. Wong, J. Li, X. Li, M.K. Deyholos, Q. Cronk. (2014) Phylogenetic pinpointing of a paleopolyploidy event within the flax genus (Linum) using transcriptomics. Ann. Bot. 113: 753-761. PMID: 24380843. DOI: 10.1093/aob/mct306

 

Tang JW, Adachi D, Gunning H, Marian-Dyer C, Hume S, Taylor S, Haase S, Vicen L, Benedet M, Chow A, Somerville M, Hicks M, Tipples G. (2015) Discrepant HIV results resolved by human DNA testing. J Clin Virol. 2014 Oct;61(2):311-2. doi: 10.1016/j.jcv.2014.06.021. Epub 2014 Jun 30.

 

Tang JW, Gao CX, Cowling BJ, Koh GC, Chu D, Heilbronn C, Lloyd B, Pantelic J, Nicolle AD, Klettner CA, Peiris JS, Sekhar C, Cheong DK, Tham KW, Koay ES, Tsui W, Kwong A, Chan K, Li (2014) Absence of detectable influenza RNA transmitted via aerosol during various human respiratory activities–experiments from Singapore and Hong Kong. PLoS One. Sep 10;9(9):e107338. doi: 10.1371/journal.pone.0107338. eCollection 2014.

 

Tang JW, Adachi D, Gunning H, Marian-Dyer C, Hume S, Taylor S, Haase S, Vicen L, Benedet M, Chow A, Somerville M, Hicks M, Tipples G. (2014) Discrepant HIV results resolved by human DNA testing. J Clin Virol. Oct;61(2):311-2. doi: 10.1016/j.jcv.2014.06.021. Epub 2014 Jun 30.

 

G. Tanifuji, N.T. Onodera, M.W. Brown, B.A. Curtis, A.J. Roger, G.K. Wong, M. Melkonian, J.M. Archibald. (2014) Nucleomorph and plastid genome sequences of the chlorarachniophyte Lotharella oceanica: convergent reductive evolution and frequent recombination in nucleomorph-bearing algae. BMC Genomics 15: 374. PMID: 24885563. DOI: 10.1186/1471-2164-15-374

 

Thomas B, Joyce M, Levin A, Tyrrell DLJ.  (2014) Validation of TaqMan® SNP Genotyping Specificity for rs12979860 of IL-28B:  Modeling Primer Specificity in-vitro. Journal of Virological Methods. 2014 Jul;203:39-47. doi: 10.1016/j.jviromet.2014.03.016. Epub 2014 Mar 27

 

Tendry RG, Bilawchuk LM, Marchant DJ. (2014) Targeting Matrix Metalloproteinase Activity and Expression for the Treatment of Viral Myocarditis. J Cardiovasc Transl Res. 2014 Jan 1. [Epub ahead of print]

 

Truong T, Boshra H, Embury-Hyatt C, Nfon C, Gerdts V, Tikoo S, Babiuk LA, Kara P, Chetty T, Mather A, Wallace DB, Babiuk S. (2014) Peste des petits ruminants virus tissue tropism and pathogenesis in sheep and goats following experimental infection. PLoS One. 9(1):e87145. doi: 10.1371/journal.pone.0087145. eCollection 2014.

 

Tsai, K, Chan, L, Gibeault, R, Conn, K, Dheekollu, J, Domsic, J, Marmorstein, R, Schang, LM and Lieberman, P (2014) Viral Reprogramming of the Daxx-Histone H3.3 Chaperone During EBV Early Infection. Journal of Virology 88(24):14350-14363.

 

Tuszynski JA, Winter P, White D, Tseng CY, Sahu K, Gentile F, Spasevska I, Omar SI, Nayebi N, Churchill CD, Klobukowski M, El-Magd RM. (2014) Mathematical and computational modeling in biology at multiple scales. Theor Biol Med Model. 2014 Dec 27;11(1):52. [Epub ahead of print]

 

Unterweger, D., Miyata, S.T., Bachmann, V., Brooks, T., Provenzano, D., Pukatzki, S. (2014) The Vibrio cholerae type VI secretion system employs diverse effector modules for intraspecific competition. Nature Communications, 5, Article number: 3549, doi:10.1038/ncomms4549.

 

van Buuren N, Burles K, Schriewer J, Mehta N, Parker S, Buller RM, Barry M. (2014) EVM005: an ectromelia-encoded protein with dual roles in NF-κB inhibition and virulence. PLoS Pathog. 2014 Aug 14;10(8):e1004326. doi: 10.1371/journal.ppat.1004326. eCollection 2014 Aug.

 

N.J. Wickett, S. Mirarab, N. Nguyen, T. Warnow, E. Carpenter, N. Matasci, S. Ayyampalayam, M.S. Barker, J.G. Burleigh, M.A. Gitzendanner, … G.K. Wong, J. Leebens-Mack (2014). Phylotranscriptomic analysis of the origin and early diversification of land plants. Proc. Natl. Acad. Sci. USA 111: E4859-E4868. PMID: 25355905. DOI: 10.1073/pnas.1323926111

 

Willows S, Ilkow CS, Hobman TC. (2014) Phosphorylation and membrane association of the Rubella virus capsid protein is important for its anti-apoptotic function. Cell Microbiol. 2014 Aug;16(8):1201-10. doi: 10.1111/cmi.12272. Epub 2014 Feb 21.

 

Wong J, Bhat R, Hockman D, Logan M, Chen C, Levin A, Frey S, Belshe RB, Tyrrell DLJ, Law JLM, Houghton M.  (2014) A recombinant HCV envelope glycoprotein vaccine elicits antibodies targeting multiple epitopes on the envelope glycoproteins associated with broad cross-neutralization.  J Virol. 2014 Dec;88(24):14278-88. doi: 10.1128/JVI.01911-14. Epub 2014 Oct 1

 

Wu B, Peisley A, Tetrault D, Li Z, Egelman EH, Magor KE, Walz T, Penczek PA, Hur S. (2014) Molecular imprinting as a signal-activation mechanism of the viral RNA sensor RIG-I. Mol Cell. 2014 Aug 21;55(4):511-23. doi: 10.1016/j.molcel.2014.06.010. Epub 2014 Jul 10.

 

Y. Xie, G. Wu, J. Tang, R. Luo, J. Patterson, S. Liu, W. Huang, G. He, S. Gu, S. Li, … G.K. Wong, J. Wang. (2014) SOAPdenovo-Trans: de novo transcriptome assembly with short RNA-Seq reads. Bioinformatics 30: 1660-1666. PMID: 24532719. DOI: 10.1093/bioinformatics/btu077

 

Yao Q, Fischer KP, Tyrrell DL, Gutfreund KS. (2014) The Pekin duck programmed death-ligand 1: cDNA cloning, genomic structure, molecular characterization and mRNA expression analysis. Int J Immunogenet. 2014 Dec 30. doi: 10.1111/iji.12175. [Epub ahead of print]

 

Yao Q, Fischer KP, Arnesen K, Tyrrell DL, Gutfreund KS. (2014) Molecular cloning, expression and characterization of Pekin duck interferon-λ. Gene. 2014 Sep 10;548(1):29-38. doi: 10.1016/j.gene.2014.06.066. Epub 2014 Jun 30.

 

Yi MinKyung, Hu Fengyu, Joyce M, Saxena V, Welsch C, Chavez D, Guerra B, Yamane D, Veselenak R, Pyles R, Walker C, Tyrrell DLJ, Bourne N, Lanford R, and Lemon S.  (2014) Evolution of a cell culture-derived genotype 1a hepatitis C virus (H77S.2) during persistent infection with chronic hepatitis in a chimpanzee. Journal of Virology.  2014 April:88(7):3678-94.  Doi: 10.1128/MVI.03540-13

 

 

2013

 

Anggakusuma, Colpitts CC, Schang LM, Rachmawati H, Frentzen A, Pfaender S, Behrendt P, Brown RJ, Bankwitz D, Steinmann J, Ott M, Meuleman P, Rice CM, Ploss A, Pietschmann T, Steinmann E. (2013) Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells. Gut. Jul 31. doi: 10.1136/gutjnl-2012-304299. [Epub ahead of print]

 

Arbuckle TE, Fraser WD, Fisher M, Davis K, Liang CL, Lupien N, Bastien S, Velez MP, von Dadelszen P, Hemmings DG, Wang J, Helewa M, Taback S, Sermer M, Foster W, Ross G, Fredette P, Smith G, Walker M, Shear R, Dodds L, Ettinger AS, Weber JP, D’Amour M, Legrand M, Kumarathasan P, Vincent R, Luo ZC, Platt RW, Mitchell G, Hidiroglou N, Cockell K, Villeneuve M, Rawn DF, Dabeka R, Cao XL, Becalski A, Ratnayake N, Bondy G, Jin X, Wang Z, Tittlemier S, Julien P, Avard D, Weiler H, Leblanc A, Muckle G, Boivin M, Dionne G, Ayotte P, Lanphear B, Séguin JR, Saint-Amour D, Dewailly E, Monnier P, Koren G, Ouellet E. (2013) Cohort profile: the maternal-infant research on environmental chemicals research platform. Paediatr Perinat Epidemiol. Jul;27(4):415-25. doi: 10.1111/ppe.12061.

 

Baginska J, Viry E, Berchem G, Poli A, Noman MZ, van Moer K, Medves S, Zimmer J, Oudin A, Niclou SP, Bleackley RC, Goping IS, Chouaib S, Janji B. (2013)Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia. PNAS Oct 22;110(43):17450-5. doi: 10.1073/pnas.1304790110. Epub 2013 Oct 7

 

Banerji A, Panzov V, Young M, Lee BE, Mamdani M, Giles BL, Dennis M, Morel J, Bisson D, Paes BA, Hui C, Mahony J. (2013) The real-life effectiveness of palivizumab for reducing hospital admissions for respiratory syncytial virus in infants residing in Nunavut. Can Respir J. Dec 23. pii: 15997. [Epub ahead of print] No abstract available

 

Barber MR, Aldridge JR Jr, Fleming-Canepa X, Wang YD, Webster RG, Magor KE. (2013) Identification of avian RIG-I responsive genes during influenza infection. Mol Immunol. May;54(1):89-97. doi: 10.1016/j.molimm.2012.10.038. Epub 2012 Dec 4

 

R. Bhanji, A Mason, A Montano-Loza.(2013) Liver transplantation for overlap syndromes of autoimmune liver diseases. Liver Int.: 33; 210-219

 

Barakat KH, Law J, Prunotto A, Magee WC, Evans DH, Tyrrell DL, Tuszynski J, Houghton M. (2013) Detailed computational study of the active site of the hepatitis C viral RNA polymerase to aid novel drug design. J. Chem. Inf. Model. 53:3031-43

 

Barakat KH, Huzil JT, Jordan KE, Evangelinos C, Houghton M, Tuszynski J. (2013) A computational model for overcoming drug resistance using selective dual-inhibitors for aurora kinase A and its T217D variant. Mol. Pharm. 10:4572-89

 

Barakat K, Houghton M, Tyrrell DLJ,  Tuszynski J.    (2013) Rational Drug Design:  One Target, Many Paths to IT.  Int. J Computational Models & Algorithms in Med.  Accepted November 2013

 

H. Bohorquez, A. Cohen, N. Girgrah, D. Bruce, I. Carmody, S. Joshi, T. Reichman, G. Therapondos, A. Mason, G. Loss. (2013) Liver transplantation in hepatitis B core negative recipients using livers from hepatitis B core positive donor: 13 years experience. Liver Transpl. 19; 611-8

 

Brooks TM, Unterweger D, Bachmann V, Kostiuk B, Pukatzki S. (2013) Lytic activity of the Vibrio cholerae type VI secretion toxin VgrG-3 is inhibited by the antitoxin TsaB. J Biol Chem. Mar 15;288(11):7618-25. doi: 10.1074/jbc.M112.436725. Epub 2013 Jan 22.

 

D.N. Burshtyn (2013) NK cells and Poxvirus Infection. Frontiers in Immunology doi:10.3389/fimmu.2013.00007

 

Cairo LV, Ptak C, Wozniak RW. (2013) Dual personality of Mad1: Regulation of nuclear import by a spindle assembly checkpoint protein. Nucleus. Sep 1;4(5):367-373. Epub 2013 Sep 27.Review.Cairo LV, Ptak C, Wozniak RW. (2013) Mitosis-specific regulation of nuclear transport by the spindle assembly checkpoint protein Mad1p. Mol Cell. Jan 10;49(1):109-20. doi: 10.1016/j.molcel.2012.10.017. Epub 2012 Nov 21.

 

Chow VT, Tipples GA, Grose C. (2013) Bioinformatics of varicella-zoster virus: single nucleotide polymorphisms define clades and attenuated vaccine genotypes. Infect Genet Evol. Aug;18:351-6. doi: 10.1016/j.meegid.2012.11.008. Epub 2012 Nov 24.

 

Colombatto P, Brunetto MR, Maina AM, Romagnoli V, Almasio P, Rumi MG, Ascione A, Pinzello G, Mondelli M, Muratori L, Rappuoli R, Rosa, D, Houghton M, Abrignani S, Bonino F. (2013) HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFNα2a and ribavirin: a randomized controlled trial. J. Viral Hepatitis. doi: 10.1111/jvh.12163

 

Colpitts CC, Ustinov AV, Epand RF, Epand RM, Korshun VA, Schang LM. (2013) 5-(Perylen-3-yl)ethynyl-arabino-uridine (aUY11), an arabino-based rigid amphipathic fusion inhibitor, targets virion envelope lipids to inhibit fusion of influenza virus, hepatitis C virus, and other enveloped viruses. J Virol. Apr;87(7):3640-54. doi: 10.1128/JVI.02882-12. Epub 2013 Jan 2

 

Congly SE, Wong P, Al-Busafi SA, Doucette K, Fung SK, Ghali P, Fonseca K, Myers RP, Osiowy C, Coffin CS. (2013) Characterization of hepatitis B virus genotypes and quantitative hepatitis B surface antigen titres in North American tertiary referral liver centres. Liver Int. Oct;33(9):1363-9. doi: 10.1111/liv.12222. Epub 2013 Jun 14

 

Conn KL, Hendzel MJ, Schang LM. (2013) The differential mobilization of histones H3.1 and H3.3 by herpes simplex virus 1 relates histone dynamics to the assembly of viral chromatin. PLoS Pathog.;9(10):e1003695. doi: 10.1371/journal.ppat.1003695. Epub 2013 Oct 10

 

Conn KL, Schang LM. (2013) Chromatin dynamics during lytic infection with herpes simplex virus 1. Viruses. Jul 16;5(7):1758-86. doi: 10.3390/v5071758. Review.

 

Davidson, C., Cameron, L. and D.N. Burshtyn (2013) The AP1 transcription factor JunD activates the Leukocyte Immunoglobulin-like Receptor 1 distal promoter. Int. Immunol., published online September 13, 2013. PMID: 24038602

 

Demczuk WH, Martin I, Griffith A, Lefebvre B, McGeer A, Lovgren M, Tyrrell GJ, Desai S, Sherrard L, Adam H, Gilmour M, Zhanel GG; Toronto Bacterial Diseases Network; Canadian Public Health Laboratory Network. (2013) Serotype distribution of invasive Streptococcus pneumoniae in Canada after the introduction of the 13-valent pneumococcal conjugate vaccine, 2010-2012. Can J Microbiol. Dec;59(12):778-88. doi: 10.1139/cjm-2013-0614. Epub 2013 Oct 21.

 

Doucette KE, Al-Saif M, Kneteman N, Chui L, Tyrrell GJ, Kumar D, Humar A. (2013) Donor-Derived Bacteremia in Liver Transplant Recipients despite Antibiotic Prophylaxis. Am. J. Transpl. Apr 13(4):1080-3

 

Duguay BA, Saffran HA, Ponomarev A, Duley SA, Eaton HE, Smiley JR. (2013) Elimination of mitochondrial DNA is not required for herpes simplex virus type 1 replication. J Virol. Dec 26. [Epub ahead of print]

 

Duguay BA, Smiley JR. (2013) Mitochondrial nucleases ENDOG and EXOG participate in mitochondrial DNA depletion initiated by herpes simplex virus 1 UL12.5. J Virol. Nov;87(21):11787-97. doi: 10.1128/JVI.02306-13. Epub 2013 Aug 28.

 

El Moghazy W, Gala-Lopez B, Wong W, Kneteman N. (2013) Recovery of locked-in syndrome following liver transplantation with calcineurin inhibitor cessation and supportive treatment. Am J Case Rep, 14:16-19.

 

Ewen CL, Kane KP, Bleackley RC. (2013) Granzyme H induces cell death primarily via a Bcl-2-sensitive mitochondrial cell death pathway that does not require direct Bid activation. Mol Immunol. Jul;54(3-4):309-18. doi: 10.1016/j.molimm.2012.12.020. Epub 2013 Jan 23

 

Feikin DR, Kagucia EW, Loo JD, Link-Gelles R, Puhan MA, Cherian T, Levine OS, Whitney CG, O’Brien KL, Moore MR; Serotype Replacement Study Group. (2013) Serotype-specific changes in invasive pneumococcal disease after pneumococcal conjugate vaccine introduction: a pooled analysis of multiple surveillance sites. PLoS Med. 10(9):e1001517. doi: 10.1371/journal.pmed.1001517. Epub 2013 Sep 24.

 

Forbrich, A., Paproski, R., Hitt, M., and Zemp, R. (2013). Microbubble-Enhanced Ultrasound Liberation of mRNA Biomarkers In Vitro. Ultrasound Med Biol. 39(6):1087-93

 

Foster JR, Lund G, Sapelnikova S, Tyrrell DL, Kneteman NM. (2013) Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies. Xenobiotica  Dec 10 Epub ahead of print. Doi:10.3109/00498254.2013.867553

 

TJ Gao, YP Tong, M Cao, XM Liand XL Pang. (2013) Evaluation of the Inactivation of Human Coxsackievirus by Thermophilic and Mesophilic Anaerobic Digestion Using Integrated Cell Culture and Reverse Transcription Real-Time Quantitative PCR. Water Research Sep 1; 47(13):4259-64

 

Golec D, Dower NA, Stone JC and Baldwin TA. (2013) RasGRP1, but not RasGRP3, is required for efficient thymic -selection and Erk activation downstream of CXCR4. PLOS ONE 8(1):e53300. doi: 10.1371

 

Gombos R, Brown J, Teefy J, Gibeault R, Conn K, Schang LM and Hemmings D. (2013) Vascular Dysfunction in Young, Mid-aged and Aged Mice with Latent Cytomegalovirus Infections. Am J Physiol Heart Circ Physiol. 304(2): H183–H194. Published online 2012 November 2. doi: 10.1152/ajpheart.00461.2012

 

Gonzales MF, Brooks T, Pukatzki SU, Provenzano D. (2013) Rapid protocol for preparation of electrocompetent Escherichia coli and Vibrio cholerae. J Vis Exp. Oct 8;(80). doi: 10.3791/50684

 

Gorfinkel IS, Aoki F, McNeil S, Dionne M, Shafran SD, Zickler P, Halperin S, Langley J, Bellamy A, Schulte J, Heineman T, Belshe R. (2013) Seroprevalence of HSV-1 and HSV-2 antibodies in Canadian women screened for enrolment in a herpes simplex virus vaccine trial. Int J STD AIDS. May;24(5):345-9. doi: 10.1177/0956462412472822

 

Graham JE, Mayan M, McCargar LJ, Bell RC; Sweet Moms Team. (2013) Making compromises: a qualitative study of sugar consumption behaviors during pregnancy. J Nutr Educ Behav. Nov-Dec;45(6):578-85. doi: 10.1016/j.jneb.2013.03.011. Epub 2013 Jul 19

 

Grebely J, Bilodeau M, Feld JJ, Bruneau J, Fischer B, Raven JF, Wong T, Roberts E, Choucha N, Myers RP, Sagan SM, Wilson JA, Bialystok F, Tyrrell DL, Houghton M, Krakden M…Kneteman N on behalf of the National CIHR Research Traing Program in Hepatitis C. The Second Canadian Symposium on Hepatitis C Virus Infection: A Call to Action. Can. J. Gastroenterol. 27:627-32

 

Gujar SA, Dielschneider R, Clements D, Helson E, Shmulevitz M, Marcato P, Pan D, Pan L, Alawadh A, Lee PWL. (2013) Multifaceted Therapeutic Targeting of Ovarian Peritoneal Carcinomatosis through Virus induced Immuno-modulation. Mol. Ther., In Press.

 

Gutfreund K, Bienias W, Szewczyk A, Kaszuba A. (2013) Topical calcineurin inhibitors in dermatology. Part I: Properties, method and effectiveness of drug use. Postepy Dermatol Alergol. Jun;30(3):165-9. doi: 10.5114/pdia.2013.35619. Epub 2013 Jun 20. Review.

 

ME. Hasing, BE. Lee, JK. Preiksaitis, R Tellier, L Honish, A Senthilselvan, XL Pang. (2013) Emergence of a New Norovirus GII.4 Variant and Changes in the Historical Biennial Pattern of Norovirus Outbreak Activity in Alberta, Canada (2008-2012). JCM, 51(7):2204-11

 

Hayden RT, Shahbazian MD, Valsamakis A, Boonyaratanakornkit J, Cook L, Pang XL, Preiksaitis JK, Schönbrunner ER, Caliendo AM. (2013) Multicenter evaluation of a commercial cytomegalovirus quantitative standard: effects of commutability on interlaboratory concordance. J Clin Microbiol. 51:3811-7

 

Hegazy SA, Alshareef A, Gelebart P, Anand M, Armanious H, Ingham RJ, Lai R. (2013) Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma. Cell Signal. Jan;25(1):295-307. doi: 10.1016/j.cellsig.2012.09.027. Epub 2012 Sep 28.

 

G. Hirschfield, R. Chapman, T. Karlson, F. Lammert, K. Lazaridis, A. Mason. (2013) The genetics of complex cholestatic disorders. Gastroenterology, 144:1357-1374

 

Huang Y, Li Y, Burt DW, Chen H, Zhang Y, Qian W, Kim H, Gan S, Zhao Y, Li J, Yi K, Feng H, Zhu P, Li B, Liu Q, Fairley S, Magor KE, Du Z, Hu X, Goodman L, Tafer H, Vignal A, Lee T, Kim KW, Sheng Z, An Y, Searle S, Herrero J, Groenen MA, Crooijmans RP, Faraut T, Cai Q, Webster RG, Aldridge JR, Warren WC, Bartschat S, Kehr S, Marz M, Stadler PF, Smith J, Kraus RH, Zhao Y, Ren L, Fei J, Morisson M, Kaiser P, Griffin DK, Rao M, Pitel F, Wang J, Li N. (2013) The duck genome and transcriptome provide insight into an avian influenza virus reservoir species. Nat Genet. Jul;45(7):776-83. doi: 10.1038/ng.2657. Epub 2013 Jun 9

 

Houghton M. (2013) Three isn’t the magic number. Nat. Med. 19:807

 

Houghton M, Law J, Tyrrell DL. (2013) An inactivated hepatitis C virus vaccine on the horizon? Gastroenterology. 145:285–8

 

Houghton M, Law LMJ, Landi A, Magee W, Tyrrell DLJ.  (2013) Progress Towards a Hepatitis C Virus Vaccine.  Emerging Microbes & Infections November E79; doi:10.1038/emi.2013/79

 

Irwin CR, Favis NA, Agopsowicz KC, Hitt MM, Evans DH. (2013) Myxoma virus oncolytic efficiency can be enhanced through chemical or genetic disruption of the actin cytoskeleton. PLoS One. Dec 31;8(12):e84134. doi: 10.1371/journal.pone.0084134

 

C. Jüngst, J. Cheng, R. Green, J. Jidong, L. Kupcinskas, A. Mason, J. Miquel, F. Lammert. (2013) Intrahepatic cholestasis in common chronic liver diseases. Eur. J. Clinical Investigation 43(10):1069-83

 

Karvellas CJ, Lescot T, Goldbert P, Sharpe MD, Ronco JJ, Renner EL, Vahidy H, Poonja Z, Chaudhury P, Kneteman NM, Selzner M, Cook FE, Bagshaw SM. (2013) Liver Transplantation in the Critically Ill: A Multi-Centre Canadian Retrospective Cohort Study. Citical Care. Feb9; 17(1) [Epub ahead of print].

 

Kawahara T, Toso C, Churchill TA, Douglas D, Nourbakhsh M, Cader, S, Lewis J, Kneteman N. (2013) Additive effect of sirolimus and anti-death receptor 5 agnoistic antibody against hepatocellular carcinoma. Liver International.  Oct;33(9):1441-8. July 08, 2013 [Epub ahead of print]

 

Kessler CS, Kane K, Dev S, Smiley JL. (2013) Inadequate postgraduate training of skin and soft tissue infections in an era of community-associated methicillin-resistant Staphylococcus aureus. J Investig Med. Aug;61(6):1026-9. doi: 10.231/JIM.0b013e31829a7a27.

 

Koehbach J, Attah AF, Berger A, Hellinger R, Kutchan TM, Carpenter EJ, Rolf M, Sonibare MA, Moody JO, Wong GK, Dessein S, Greger H, Gruber CW. (2013) Cyclotide discovery in Gentianales revisited-identification and characterization of cyclic cystine-knot peptides and their phylogenetic distribution in Rubiaceae plants. Biopolymers. Sep;100(5):438-52. doi: 10.1002/bip.22328

 

Kotton CN, Kumar D, Caliendo AM, Asberg A, Chou S, Danziger-Isakov L, Humar A; Transplantation Society International CMV Consensus Group. (2013) Updated international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation. Transplantation. Aug 27;96(4):333-60. doi: 10.1097/TP.0b013e31829df29d

 

Lai R, Ingham RJ. (2013) The pathobiology of the oncogenic tyrosine kinase NPM-ALK: a brief update. Ther Adv Hematol. Apr;4(2):119-31. doi: 10.1177/2040620712471553.

 

Lam TT, Chong YL, Shi M, Hon CC, Li J, Martin DP, Tang JW, Mok CK, Shih SR, Yip CW, Jiang J, Hui RK, Pybus OG, Holmes EC, Leung FC. (2013) Systematic phylogenetic analysis of influenza A virus reveals many novel mosaic genome segments. Infect Genet Evol. Aug;18:367-78. doi: 10.1016/j.meegid.2013.03.015

 

Landi A, Weismuller TJ, Lankisch TO, Santer DM, Tyrrell DL, Manns MP, Houghton M. (2013) Differential serum levels of eosinophilic eotaxins in primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis. J. Interferon Cytokine Res. Oct 29. [Epub ahead of print]

 

Law LMJ, Landi A, Magee WC, Tyrrell DL, Houghton M. (2013) Progress towards a hepatitis C virus vaccine. Emerging Microbes & Infections. 2:e79. doi:10.1038/emi.2013.79

 

J. Law, J. Jovel, J. Patterson, G. Ford, S. O’Keefe , W. Wang, Bo Meng, D. Song, Y. Zhang, Z. Tian, S. Wasilenko, M. Rahbari, Troy Mitchell, T. Jordan, E. Carpenter,  A. Mason,  G. Wong. (2013) Identification of hepatotropic viruses from plasma using deep sequencing: a next generation diagnostic tool. PLOS One 17;8(4):e60595

 

Law JLM, Chen C, Wong J, Hockman D, Santer DM, Frey SE, Belshe RB, Wakita T, Bukh J, Jones CT, Rice CM, Abrignani S, Tyrrell DL, Houghton M. (2013) A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans. PLoS ONE. 8:e59776. doi:10.1371/journal.pone.0059776

 

Law JLM, Chen C, Wong J, Hockman D, Santer D, Frey SE, Belshe RB, Wakita T, Bukh J, Rice CM, Jones CT, Abrignani S, Tyrrell DLJ, Houghton M.  (2013) A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans.  PloS One  8(3):e59776. doi: 10.1371/journal.pone.0059776. Epub 2013 Mar 19

 

Lee BE and Pang XL.  (2013) New strains of norovirus and the mystery of viral gastroenteritis epidemics. CMAJ Nov 5;185(16):1381-2

 

Lee HK, Tang JW, Kong DH, Koay ES. (2013) Simplified Large-Scale Sanger Genome Sequencing for Influenza A/H3N2 Virus. PLoS One. May 31;8(5):e64785. doi: 10.1371/journal.pone.0064785

 

Lee HK, Tang JW, Kong DH, Loh TP, Chiang DK, Lam TT, Koay ES. (2013) Comparison of Mutation Patterns in Full-Genome A/H3N2 Influenza Sequences Obtained Directly from Clinical Samples and the Same Samples after a Single MDCK Passage. PLoS One. Nov 1;8(11):e79252. doi: 10.1371/journal.pone.0079252

 

Lee JK, Pearson JD, Maser BE, Ingham RJ. (2013) Cleavage of the JunB transcription factor by caspases generates a carboxyl-terminal fragment that inhibits activator protein-1 transcriptional activity. J Biol Chem. Jul 26;288(30):21482-95. doi: 10.1074/jbc.M113.485672. Epub 2013 Jun 9.

 

Li, J., Hobman, T.C., and Simmonds, A.J. (2013) Gawky (Gw) is the Drosophila melanogaster GW182 homologue. Adv Edp Med Biol 768: 127-45

 

Li, N.L., Fu, L., Uchtenhagen, H., A. Achour and D.N. Burshtyn. (2013) Cis Association of Leukocyte Ig-Like Receptor 1 with MHC Class I Modulates Accessibility to Antibodies and HCMV UL18. Eur. J. Immunol. doi: 10.1002/eji.201242607

 

Z. Lin, A. Farooqui, G. Li, G.K. Wong, A.L. Mason, D. Banner, A.A. Kelvin, D.J. Kelvin, A.J. León. IN PRESS. Next-generation sequencing and bioinformatic approaches to detect and analyze influenza virus in ferrets. J. Infect. Dev. Ctries.

 

Ling J, Lewis J, Douglas D, Kneteman NM, Vance DE. (2013) Characterization of lipid and lipoprotein metabolism in primary human hepatocytes. Biochim Bioplys Acta.  Feb;1831(2):387-97, 2012 Aug 23 [Epub ahead of print]

 

Lipinski T, Fitieh A, St Pierre J, Ostergaard HL, Bundle DR, Touret N. (2013) Enhanced immunogenicity of a tricomponent mannan tetanus toxoid conjugate vaccine targeted to dendritic cells via Dectin-1 by incorporating β-glucan. J Immunol. Apr 15;190(8):4116-28. doi: 10.4049/jimmunol.1202937. Epub 2013 Mar 20.

 

Liu J, Hov J, Folseraas T, Ellinghaus E, Rushbrook S, Doncheva N, Andreassen O, et al. (2013) Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nature Genetics 45(6):670-5

 

Kawahara T, Dogulas D, Nourbkahsh M, Lewis J, Cader S, Kneteman N. (2013) Human cytomegalovirus infection in humanized liver chimeric mice. Hepatology Research Jun;43(6):4089-97. 2012 Oct. 18 [Epub ahead of print]

 

J. Koehbach, A.F. Attah, A. Berger, R. Hellinger, T.M. Kutchan, E.J. Carpenter, M. Rolf, M.A. Sonibare, J.O. Moody, G.K. Wong, et al. (2013) Cyclotide discovery in Gentianales revisited – identification and characterization of cyclic cystine-knot peptides and their phylogenetic distribution in Rubiaceae plants. Biopolymers 100: 438-452. PMID: 23897543

 

Magor KE, Miranzo Navarro D, Barber MR, Petkau K, Fleming-Canepa X, Blyth GA, Blaine AH. (2013) Defense genes missing from the flight division. Dev Comp Immunol. Nov;41(3):377-88. doi: 10.1016/j.dci.2013.04.010. Epub 2013 Apr 24

 

Makio T, Lapetina DL, Wozniak RW. (2013) Inheritance of yeast nuclear pore complexes requires the Nsp1p subcomplex. J Cell Biol. Oct 28;203(2):187-96. doi: 10.1083/jcb.201304047

 

Malloch L, Kadivar K, Putz J, Levett PN, Tang J, Hatchette TF, Kadkhoda K, Ng D, Ho J, Kim J. (2013) Comparative evaluation of the Bio-Rad Geenius HIV-1/2 Confirmatory Assay and the Bio-Rad Multispot HIV-1/2 Rapid Test as an alternative differentiation assay for CLSI M53 algorithm-I. J Clin Virol. Dec; 58 Suppl 1:e85-91. doi: 10.1016/j.jcv.2013.08.008

 

Manage DP , Lauzon J, Atrazhev A , Pang XL , Pilarski LM (2013) A novel method for sample delivery and testing of whole blood: gel strip PCR for point of care (POC) molecular diagnostics., Lab on a chip. Oct 21;13(20):4011-4

 

A. Mason A. Montano-Loza. (2013) Systematic Investigation of Elevated Cholestatic Enzymes During the Third Post-Transplant Month. Liver Transpl.  19 Suppl 2:S23-30

 

Mereniuk, T.R., El Gendy, M.A.M., Mendes-Pereira, A.M., Lord, C.J., Ghosh, S., R., Foley, E., Unsworth, A., and Weinfeld M. (2013) Synthetic lethal targeting of PTEN-deficient cancers using selective disruption of polynucleotide kinase/phosphatase. Molecular Cancer Therapeutics. 12:2135-2144

 

Minuk GY, O’Brien M, Hawkins K, Emokpare D, McHattie J, Harris P, Worobetz L, Doucette K, Kaita K, Wong S, Pinette G, Uhanova J.  (2013) Treatment of chronic hepatitis C in a Canadian Aboriginal population: Results from the PRAIRIE study. Can J Gastroenterol. Dec;27(12):707-10

 

Molavi L, Xiao-Bing X, Douglas D, Kneteman N Satosi N, Pastan I, Chu Q, Lavasanifar A, Lai R. (2013) Anti-CD30 antibody conjugated liposomal doxorubicin with significantly improved therapeutic efficacy against anaplastic large cell lymphoma. Biomaterials July 34(34):8718-25

 

Morard I, Gasche Y, Mark K, Toso C, Mentha A, MeebergG, Mentha G, Kneteman N, Giorstra E. (2013) Identifying risk factors for central pontine and extrapontine myelinolysis after liver transplantation: a case-control study. Neurocrit Care Nov 14 [Epub ahead of print]

 

Miyata ST, Unterweger D, Rudko SP, Pukatzki S. (2013)Dual Expression Profile of Type VI Secretion System Immunity Genes Protects Pandemic Vibrio cholerae. PLoS Pathog. Dec;9(12):e1003752. doi: 10.1371/journal.ppat.1003752. Epub 2013 Dec 5

 

Miyata ST, Bachmann V, Pukatzki S. (2013) Type VI secretion system regulation as a consequence of evolutionary pressure. J Med Microbiol. May;62(Pt 5):663-76. doi: 10.1099/jmm.0.053983-0. Epub 2013 Feb 21. Review.

 

Narkewicz MR, Green M, Dunn S, Millis M, McDiarmid S, Mazariegos G, Anand R, Ying W for the Studies of Pediatric Liver Transplantation Research Group. (2013) Decreasing Incidence of Symptomatic Epstein-Barr Virus Disease and Posttransplant Lymphoproliferative Disorder in Pediatric Transplant Recipients: Report of the Studies of Pediatric Liver Transplantation Experience. Liver Transplant July 19(7):730-40

 

Nasheri N, Joyce MA, Rouleau Y, Yang P, Yao S, Tyrrell DLJ, and Pezacki JP.  (2013) Modulation of Fatty Acid Synthase Enzyme Activity and Expression during Hepatitis C Virus Replication.  Chemistry & Biology 20:April 18:20(4):570-82. doi:10.1016/j.chembiol.2013.03.014

 

Neufeldt CJ, Joyce MA, Levin A, Steenbergen RH, Pang D, Shields J, Tyrrell DLJ, and Wozniak RW.  (2013) Hepatitis C virus-induced cytoplasmic organelles use the nuclear transport machinery to establish an environment conducive to virus replication. PLOS Pathogens 31 Oct;  info:doi/10.1371/journal.ppat.1003744

 

Ng KH, Quak ZX, Chan YH, Suhaila M, Lau PY, Tambyah PA, Tang JW, Yap HK. (2013) Benign clinical course in H1N1 2009 influenza infection in young oseltamivir-treated immunocompromised patients with kidney disease in Singapore. Pediatr Infect Dis J. Mar;32(3):298-300. doi: 10.1097/INF.0b013e31827d77dc

 

Nourbakhsh M, Douglas DN, Pu CH, Lewis JT, Kawahara T, Lisboa LF, Wei E, Asthana S, Quiroga AD, Law LM, Chen C, Addison WR, Nelson R, Houghton M, Lehner R, Kneteman NM. (2013) Arylacetamide deacetylase: A novel host factor with important roles in the lipolysis of cellular triacylglycerol stores, VLDL assembly and HCV production. J. Hepatol. 59:336–43

 

Nourbakhsh M, Douglas D, Lewis J, Hao C, Kawahara T, Nelson R, Lehner R, Kneteman N. (2013) Arylacetemide deacetylase: A triacylglycerol lipase that is ablated in hepatoma cells during infectious Hepatitis C viral production. J Hepatology 28 March [Epub ahead of print]

 

Pan D, Marcato P, GyunAhn D, Gujar S, Pan LZ, Shmulevitz M, Lee PWL. (2013) Activation of p53 by Chemotherapeutic Agents Enhances Reovirus Oncolysis. PLOS ONE, In Press.

 

Pang XL, Preiksaitis JK, and Lee BE. (2013) Enhanced enteric virus detection in sporadic gastroenteritis using a multi-target real-time PCR panel – A one-year study. J Medical Virology. Nov 14. doi: 10.1002/jmv.23851. [Epub ahead of print]

 

Pare, J.M., LaPointe, P. and Hobman, T.C. (2013) Hsp90 co-chaperones p23 and FKBP4 physically interact with hAgo2 and activate RNAi-mediated silencing in mammalian cells. Mol Biol Cell 24: 2303-2310

 

Parsons, D.B., and Foley, E. (2013) The Drosophila PDGF and VEGF-receptor related (Pvr) pathway controls hemocyte viability and epithelial permeability to invasive hemocytes. J Biol. Chem. 288(28): 20173-83

 

Mangala Prasad, V., Willows, S.D., Fokine, A., Battisti, A. J., Sun, S., Plevka, P., Hobman, T.C.,Rossmann, M.G. (2013) Rubella virus capsid protein structure and its role in virus assembly and infection.  Proc. Natl. Acad. Sci Nov 26. [Epub ahead of print]

 

Pukatzki S, Provenzano D. (2013) Vibrio cholerae as a predator: lessons from evolutionary principles. Front Microbiol. Dec 10;4:384. doi: 10.3389/fmicb.2013.00384

 

Qi X, Chanderbali AS, Wong GK, Soltis DE, Soltis PS. (2013) Phylogeny and evolutionary history of glycogen synthase kinase 3/SHAGGY-like kinase genes in land plants. BMC Evol Biol. Jul 8;13:143. doi: 10.1186/1471-2148-13-143

 

Qin L, Liang M, Evans DH. (2013) Genomic analysis of vaccinia virus strain TianTan provides new insights into the evolution and evolutionary relationships between Orthopoxviruses. Virology. 2013 Jul 20;442(1):59-66. doi: 10.1016/j.virol.2013.03.025. Epub 2013 Apr 19

 

Qiu Y, Yuan T, Kon T, Zurawell R, Huang Y, Graham M, Gabos S and Pang XL. (2013) Rapid Detection and Quantitation of Microcystin-Producing Microcystis Using Real-Time PCR. J Mol Biomark Diagn S5: 006 doi: 10.4172/2155-9929.S5-006

 

Ragonnet-Cronin M, Lee BE, Plitt SS, Zahariadis G, Merks H, Sandstrom PA, Brooks JI. (2013) Baseline clinical HIV genotypes are a valid measure of transmitted drug resistance within the treatment-naive population. J Acquir Immune Defic Syndr. Dec 15;64(5):443-7. doi: 10.1097/QAI.0b013e3182a4b991

 

Robertson CM, Dinu IA, Joffe AR, Alton GY, Yap JY, Asthana S, Acton BV, Sauve RS, Martin SR, Kneteman NM, Gilmour SM, Western Canadian Therapies Follow –up Group. (2013) Neurocognitive outcomes at kindergarten entry after liver transplantation at <3 yr of age. Pediatr Transplant Nov;17(7):621-30, 2013  Aug 21 [Epub ahead of print]

 

Rothfels CJ, Larsson A, Li FW, Sigel EM, Huiet L, Burge DO, Ruhsam M, Graham SW, Stevenson DW, Wong GK, Korall P, Pryer KM. (2013) Transcriptome-mining for single-copy nuclear markers in ferns. PLoS One. Oct 8;8(10):e76957. doi: 10.1371/journal.pone.0076957

 

Rudnick W, Liu Z, Shigayeva A, Low DE, Green K, Plevneshi A, Devlin R, Downey J, Katz K, Kitai I, Krajden S, Ostrowska K, Richardson D, Richardson S, Sarabia A, Silverman M, Simor AE, Tyrrell G, McGeer A; Toronto Invasive Bacterial Diseases Network. (2013) Pneumococcal vaccination programs and the burden of invasive pneumococcal disease in Ontario, Canada, 1995-2011. Vaccine. Dec 2;31(49):5863-71. doi: 10.1016/j.vaccine.2013.09.049. Epub 2013 Oct 5.

 

Sailba F, De Simone P, Nevens F, De Carlis L, Metselaar HJ, Beckebaum S, Jonas S, Sudan D, Fischer L, Duvoux C, Chavin KD, Kornru B, Huang MS, Chapman WC, Foltys D, Dong G, Lopez PM, Fung J, Jung G, for the H2304 Study Group. (2013) Renal Function at Two Years in Liver Transplant Patients Receiving Everolimus: Results of a Randomized, Multicenter Study. Am J Transplant. July;13(7):1734-45

 

Santer DM, Ma MM, Hockman D, Landi A, Tyrrell DL, Houghton M. (2013) Enhanced activation of memory, but not naïve, B cells in chronic hepatitis C virus-infected patients with cryoglobulinemia and advanced liver fibrosis. PLoS ONE. 8:e68308. doi: 10.1371/journal.pone.0068308

 

Sayou C, Monniaux M, Nanao MH, Moyroud E, Brockington SF, Thévenon E, Chahtane H, Warthmann N, Melkonian M, Zhang Y, Wong GK, Weigel D, Parcy F, Dumas R. (2014) A Promiscuous Intermediate Underlies the Evolution of LEAFY DNA Binding Specificity. Science. Jan 16. [Epub ahead of print]

 

Shafran DM, Shafran SD. (2013) Treating Clostridium difficile infection. CMAJ. Dec 16. [Epub ahead of print] No abstract available.

 

Shahin M, Soudy R, Aliabadi HM, Kneteman N, Kaur K, Lavasanifar A. (2013) Engineered breast tumor targeting peptide ligand modified liposomal doxorubicin and the effect of Peptide density on anticancer activity. Biomaterial May;34(16):4089-97. [Epub 2013 Mar 5]

 

Sharon, D., Schümann, M., MacLeod, S.H., McPherson, R., Chaurasiya, S., Shaw, A., and Hitt, M.M. (2013) 2-Aminopurine Enhances the Oncolytic Activity of an E1b-Deleted Adenovirus in Hepatocellular Carcinoma Cells (PLoS ONE 2013 8(6):e65222)

 

Schindler, A., and Foley, E. (2013) Hexokinase 1 blocks apoptotic signals at the mitochondria. Cellular Signalling. 25: 2685-2692

 

Singaravelu R, Chen R, Lyn RK, Jones DM, O’Hara S, Rouleau Y, Cheng J, Srinivasan P, Nasheri N, Russell RS, Tyrrell DLJ. Pezacki JP.  (2013) Hepatitis C virus induced up-regulation of microRNA-27:  A Novel Mechanism for Hepatic Steatosis.  Hepatology.  Jul 29. doi: 10.1002/hep.26634. [Epub ahead of print]

 

Singaravelu R, Lyn RK, Srinivasan P, Delcorde J, Steenbergen R, Tyrrell DLJ, Pezacki JP.  (2013) Human serum activates CIDEB-mediated lipid droplet enlargement in hepatoma cells.  BBRC. Nov 15;441(2):447-52. doi: 10.1016/j.bbrc.2013.10.080. Epub 2013 Oct 24.

 

Singh AE, Lee B, Fenton J, Preiksaitis J. (2013) The INSTI HIV-1/HIV-2 antibody test: a review. Expert Opin Med Diagn. May;7(3):299-308. doi: 10.1517/17530059.2013.774370. Epub 2013 Feb 25

 

Steenbergen RH, Joyce MA, Thomas BS, Jones D, Law J, Russell R, Houghton M, Tyrrell DL. (2013) Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers. Hepatology. 58:1907-17 doi:10.1002/hep.26566

 

St-Pierre J, Ostergaard HL. (2013) A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation. PLoS One. Jul 31;8(7):e71531. doi: 10.1371/journal.pone.0071531. Print 2013.

 

Strunk U, Saffran HA, Wu FW, Smiley JR. (2013) Role of herpes simplex virus VP11/12 tyrosine-based motifs in binding and activation of the Src family kinase Lck and recruitment of p85, Grb2, and Shc. J Virol. Oct;87(20):11276-86. doi: 10.1128/JVI.01702-13. Epub 2013 Aug 14.

 

Sulkowski MS, Bourlière M, Bronowicki JP, Asselah T, Pawlotsky JM, Shafran SD, Pol S, Mauss S, Larrey D, Datsenko Y, Stern JO, Kukolj G, Scherer J, Nehmiz G, Steinmann GG, Böcher WO. (2013) Faldaprevir combined with peginterferon alfa-2a and ribavirin in chronic hepatitis C virus genotype-1 patients with prior nonresponse: SILEN-C2 trial. Hepatology. Jun;57(6):2155-63. doi: 10.1002/hep.26386.

 

S. Sveinsson, J. McDill, G.K. Wong, J. Li, X. Li, M.K. Deyholos, Q. Cronk. IN PRESS. Phylogenetic pinpointing of a paleopolyploidy event within the flax genus (Linum) using transcriptomics. Ann. Bot.

 

Takebe Y, Saucedo CJ, Lund G, Uenishi R, Hase S, Tsuchiura T, Kneteman N, Ramessar K, Tyrrell DLJ, Shirakura M, Wakita T, McMahon JB, O’Keefe BR. (2013) Antiviral Lectins from red and blue-gree algae show potent in vitro and invivo activity against hepatitis C virus. PLOS One May; Vol 8. Issue 5, 364449; Doi 10.1371/journal.pone.0064449. Print 2013

 

Urbanowski, M.D. and Hobman, T.C. (2013) ­­The West Nile Virus Capsid Protein Blocks Apoptosis through a Phosphatidylinositol 3-kinase-dependent Mechanism. J. Virol. 87: 872-881

 

Tang JW. (2013) Phylogenetic studies of frequently diagnostically sampled herpesviruses – Possibilities for clinical applications? Infect Genet Evol. Aug;18:379-86. doi: 10.1016/j.meegid.2012.10.013

 

Tang JW, Nicolle AD, Klettner CA, Pantelic J, Wang L, Suhaimi AB, Tan AY, Ong GW, Su R, Sekhar C, Cheong DD, Tham KW. (2013) Airflow dynamics of human jets: sneezing and breathing – potential sources of infectious aerosols. PLoS One. 2013;8(4):e59970

 

Tang JW, Nicolle A, Pantelic J, Klettner CA, Su R, Kalliomaki P, Saarinen P, Koskela H, Reijula K, Mustakallio P, Cheong DK, Sekhar C, Tham KW. (2013) Different types of door-opening motions as contributing factors to containment failures in hospital isolation rooms. PLoS One. Jun 24;8(6):e66663. doi: 10.1371/ journal.pone.0066663

 

Tang JW. 92013) The stealth virus. Emerg Infect Dis. Jul;19(7):1182. doi: 10.3201/eid/1907.130027

 

Tang JW, Lam TT, Lemey P. (2013) Special Issue for the Workshop on Phylogenetics for Infectious Diseases – With a focus on DNA viruses, Institute of Mathematical Sciences, National University of Singapore, Singapore, 10-14 October 2011. Infect Genet Evol. Aug;18:349-50. doi: 10.1016/j.meegid.2013.07.005

 

Tang JW. (2013) Cytomegaloviruses: From Molecular Pathogenesis to Intervention. Emerg Infect Dis. Nov; 19(11):1906

 

Teferi WM, Dodd K, Maranchuk R, Favis N, Evans DH. (2013) A whole-genome RNA interference screen for human cell factors affecting myxoma virus replication. J Virol. 2013 Apr;87(8):4623-41. doi: 10.1128/JVI.02617-12. Epub 2013 Feb 13

 

Thomas B, Joyce M, Levin A, Tyrrell DLJ.  (2013) Validation of TaqMan® SNP Genotyping Specificity for rs12979860 of IL-28B:  Modeling Primer Specificity in-vitro. J Virol. Methods.  Accepted December 2013

 

Teperman L, Moonka D, Sebastian A, Sher L, Marotta P, Marsh C, Koneru B, Goss J, Preston D, Roberts JP; Spare-the –Nephron Trial Liver Transplantation Study Group. (2013) Calcineurin inhibitor-gree mycophenolate mofetil/sirolimus maintenance in liver transplantation: the randomized spare-the-nephron trial. Liver Transpl. July; 19(7):675-89

 

Toso C, Cader S, Mentha -Dugerdil A,  Meeberg G, Majno Pietro E, Morard I, Giostra E, Berney T, Morel P, Mentha G, Kneteman N. (2013) Factors predicting survival afer post-transplant hepatocellular carcinoma recurrenc e.  J Hepatobiliary Pancreatic Sci. Mar;20(3):342-7, 2012 June 19 [Epub ahead of print] Errattum 2013 Jun;20(5):547-8

 

Van de Vosse DW, Wan Y, Lapetina DL, Chen WM, Chiang JH, Aitchison JD, Wozniak RW. (2013) A role for the nucleoporin Nup170p in chromatin structure and gene silencing. Cell. Feb 28;152(5):969-83. doi:

 

Wang, Y., Mercier, R., Hobman, T.C., and LaPointe, P. (2013) Regulation of RNA interference by Hsp90 is an evolutionarily conserved process. Biochim Biophys Acta – Mol Cell Res 1833: 2673-2681

 

S. Wasilenko, A. Montano-Loza, A. Mason, (2013) Is there a Role for Cyclophilin Inhibitors in the Management of Primary Biliary Cirrhosis? Viruses 5(2);423-438

 

Weber BS, Miyata ST, Iwashkiw JA, Mortensen BL, Skaar EP, Pukatzki S, Feldman MF. (2013) Genomic and functional analysis of the type VI secretion system in Acinetobacter. PLoS One.;8(1):e55142. doi: 10.1371/journal.pone.0055142. Epub 2013 Jan 24.

 

Willows, S., Hou, S. and Hobman, T.C. (2013) RNA Virus Capsid proteins: More than just a Shell. Future Virology 8: 435-450

 

Wu F, Ye X, Wang P, Jung K, Wu C, Douglas D, Kneteman N, Bigras G, Lai R. (2013) Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity. BCM Cancer, July 1;13:317 [Epub ahead of print]

 

Yao Q, Fischer KP, Arnesen K, Tyrrell DLJ, Gutfreund KS.  (2013) The Pekin duck IL-10R2 common chain:  cDNA cloning, genomic structure, molecular characterization and mRNA expression analysis.  Int. J. Immunogenetics  Jan 21. doi: 10.1111/iji.12042. [Epub ahead of print]

 

E. Yoshida, L. B. Lilley, P. J. Marotta, A. L. Mason, M Bilodeau, M. Vaillancourt. (2013) A Canadian national retrospective chart review comparing the long term effects of Cyclosporine versus Tacrolimus on clinical outcomes in patients with post-liver transplantation hepatitis C virus infection. Annals of Hepatology, 12(2):282-93

 

Zhao L, Tyrrell DLJ.   (2013) Myeloid Dendritic Cells Can Kill T Cells During Chronic Hepatitis C Virus Infection.  Viral Immunology. Feb;26(1):25-39. doi: 10.1089/vim.2012.0058. Epub 2013 Feb 1

 

A Viral Debate. International Innovation, 2013;19:43-45

 

 

2012

en U, Preiksaitis J. (2012) AST Infectious Diseases Community of Practice. Epstein-Barr Virus and Post-Transplant Lymphoproliferative Disorder. Am J Transplant [in press].

 

Andres A, Gerstel E, Combescure C, Asthana S, Merani S, Majno P, Berney T, Morel P, Kneteman N, Mentha G, Toso C. (2012) A score predicting survival after liver retransplantation for Hepatitis C virus cirrhosis. Transpl. 93(7):717-22. Epub ahead of print 19 January 2012

 

Awate S, Wilson HL, Lai K, Babiuk LA, and Mutwiri G. (2012) Activation of adjuvant core response genes by the novel adjuvant PCEP. Mol Immunol. 51(3-4):292-303. Epub 2012 Apr 21

 

Barber, MRW, Adridge Jr. JR, Fleming-Canepa X, Wang Y-D, Webster RG and Magor KE. (2012) Identification of avian RIG-I responsive genes during influenza infection. Mol. Immunol.; in press

 

Basu R, Fan D, Kandalam V, Lee J, Das S, Wang X, Baldwin TA, Oudit GY, Kassiri Z. (2012) Loss of Timp3 leads to abdominal aortic aneurysm formation in response to angiotensin II. J Biol. Chem. Nov 9. [Epub ahead of print]

 

Bhanji R, Mason A, Montano-Loza A. (2012) Liver transplantation for overlap syndromes of autoimmune liver diseases. Liver International in press

 

Bond D, and Foley E (2012) Autocrine Pvr Pathway Activity Controls Intestinal Stem Cell Proliferation in the Adult Drosophila Midgut. J Biol. Chem. 287: 27359-27370. First Published on June 21, 2012, doi:10.1074/jbc.M112.378018

 

Brown R, Hudson N, Wilson G, Rehman SU, Jabbari S, Hu K, Tarr A, Borrow P, Joyce MA, Lewis J, Zhu LF, Law M, Kneteman N, Tyrrell DLJ, McKeating J, and Ball J.  (2012) Hepatitis C virus envelope glycoprotein fitness defines virus population composition following transmission to a new host.  J Virol. 2012 November 86:11956-11966

 

Buchanan RM, Popowych Y, Arsic N, Townsend HG, Mutwiri GK, Potter AA, Babiuk LA, Griebel PJ, and Wilson HL. (2012) B-cell activating factor (BAFF) promotes CpG ODN-induced B cell activiation and proliferation. Cell Immunol. 271: 16-28

 

Buchanan R, Popowych Y, Dagenais C, Arsic N, Mutwiri GK, Potter AA, Babiuk LA, Griebel PJ, and Wilson HL. (2012) Interferon-gamma and B-cell Activating Factor (BAFF) promote bovine B cell activation independent of TLR9 and T-cell signaling. Vet Immunol Immunopathol. 145(102):453-63

 

Dar A, Lai K, Dent D, Potter AA, Gerdts V, Babiuk LA, and Mutwiri G. (2012) Administration of Poly[di(sodium carboxylatoethylphenoxy)]phosphazene (PCEP) as adjuvant activated mixed Th1/Th2 immune responses in pigs. Vet Immunol Immuopathol 15;146(3-4):289-95. Epub 2012 Feb 6

 

Earn DJD, He DH, Loeb MB, Fonseca K, Lee BE, Dushoff J.  (2012) Effects of school closure on pandemic influenza incidence in Alberta, Canada.  Ann Intern Med 156:173-81

 

Egli A, Fuller J, Humar A, Lien D, Weinkauf J, Nador R, Kapasi A, Kumar D. (2012) Emergence of Aspergillus calidoustus infection in the era of posttransplantation azole prophylaxis. Transpl. 94(4):403-10. doi: 10.1097/TP.0b013e31825992f0.

 

Egli A, Silva M Jr, O’Shea D, Wilson LE, Baluch A, Lisboa LF, Hidalgo LG, Kumar D, Humar A. (2012) An Analysis of Regulatory T-Cell and Th-17 Cell Dynamics during Cytomegalovirus Replication in Solid Organ Transplant Recipients. PLoS One. 7(11):e43937. doi: 10.1371/journal.pone.0043937. Epub 2012 Oct 11

 

Egli A, Humar A, Kumar D. (2012) State-of-the-art on Monitoring of Cytomegalovirus-Specific Cell mediated immunity after Organ Transplant: A Primer for the Clinician. Clin. Infect.Dis. [Epub ahead of print]

 

Egli A, Kumar D, Humar A. (2012) Comparison of the effect of Standard and novel Immunosuppressive Drugs on CMV-specific T-cell Cytokine profiling. Transplant. (in press)

 

Emery VC, Manuel O, Asberg A, Pang X, Kumar D, Hartmann A, Preiksaitis JK, Pescovitz MD, Rollag H, Jardine AG, Gahlemann CG, Humar A. (2012) Differential decay kinetics of human cytomegalovirus glycoprotein B genotypes following antiviral chemotherapy. J Clin Virol.54(1):56-60. Epub 2012 Mar 10

 

El Moghazy W, Kashkoush S, Meeberg G, Kneteman N. Incidence, Characteristics and Prognosis of Incidentallly-Discovered Hepatocellular Carcinoma after Liver Transplantation. Liver Transplantation. Submitted December 2012

 

Engels EA, Preiksaitis JK, Zingone A, Landgren O. (2012) Circulating Antibody Free Light Chains and Risk of Posttransplant Lymphoproliferative Disorder. AJ Transpl. 12:1268-1274

 

Ewen, C.L., Kane K and  Bleackley RC. (2012) A quarter century of granzymes. Cell Death&Differentiation. 19(1):28-35

 

Fang Y, Banner D, Kelvin AA, Huang SS, Paige CJ, Corfe SA, Kane KP, Bleackley RC, Rowe T, Leon AJ, Kelvin DJ. (2012) Seasonal H1N1 infection induces cross protective pandemic N1N1 immmunity through a CD8 independent, B cell dependent mechanism. J. Virol. 86(4) :2229-38

 

Fathima S, Lee BE, May-Hadford J, Mukhi S, Drews SJ.  (2012) Use of an Innovative Web-Based Laboratory Surveillance Platform to Analyze Mixed Infections Between Human Metapneumovirus (hMPV) and Other Respiratory Viruses Circulating in Alberta (AB), Canada (2009–2012).  Viruses — Open Access Journal 4(11): 2754–2765. Published online 2012 November 5. doi: 10.3390/v4112754

 

Garlapati S, Garg R, Brownlie R, Latimer L, Simko E, Hancock RE, Babiuk LA, Gerdts V, Potter A, and van Drunen Little-van den Hurk S. (2012) Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles. Vaccine. 30(35):5206-14. Epub 2012 Jun 17

 

Gelebart P, Hegazy SA, Wang P, Bone KM, Anand M, Sharon D, Hitt M, Pearson JD, Ingham RJ, Ma Y, Lai R (2012). Aberrant expression and biological significance of Sox2, an embryonic stem cell transcriptional factor, in ALK-positive anaplastic large cell lymphoma. Blood Cancer J. 10;2:e82. doi: 10.1038/bcj.2012.27

 

Gratrix J, Plitt S, Lee BE, Ferron L, Anderson A, Verity R, Prasad E, Bunyan R, Zahariadis G, Singh AE.  (2012) Impact of Reverse Sequence Syphilis Screening on New Diagnoses of Late Latent Syphilis in Edmonton, Canada.  Sex Transm Dis (In press).

 

Gujar SA, Dielschneider R, Clements D, Helson E, Shmulevitz M, Marcato P, Pan D, Pan L, Alawadh A, Lee PWL. (2012) Multifaceted Therapeutic Targeting of Ovarian Peritoneal Carcinomatosis through Virus induced Immuno-modulation. Molecular Therapy, In Press

 

Hegazy SA, Alshareef A, Gelebart P, Anand M, Armanious H, Ingham RJ, Lai R. (2012) Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma. Cellular Signalling. 25(1):295-307

 

Hirschfield GM, Xie G, Lu E, Sun Y, Juran BD, Chellappa V, Coltescu C, Mason AL, Milkiewicz P, Myers RP, Odin JA, Luketic VA, Bacon B, Bodenheimer H, Liakina V, Vincent C, Levy C (2012) Association of primary biliary cirrhosis with variants in the CLEC16A, SOCS1, SPIB and SIAE immunomodulatory genes. Genes and Immunity 13;328-335

 

Hobman TC. (2012) Rubella in Fields Virology (Sixth Edition) (eds. D.M. Knipe and P.M. Howley). Lippincott, Williams and Wilkins, Philadelphia. (in press)

 

Hodgson PD, Aich P, Stookey J, Popowych Y, Potter A, Babiuk LA, and Griebel PJ. (2012) Stress significantly increases mortality following a secondary bacterial respiratory infection. Vet Res. 43(1):21

 

Houghton M (2012) Chimp Virus makes a savvy vaccine vector. Sci Transl. Med. Jan 4; 4(115):115fs1

 

Hu Q, Nicol SA, Suen AYW and Baldwin TA. (2012) Examination of thymic positive and negative selection by flow cytometry. J Visualized Experiments. (68). doi:pii: 4269. 10.3791/4269

 

Irwin C, and Evans DH.  (2012) Modulation of the myxoma virus plaque phenotype by vaccinia virus F11 protein.J Virol.  86(13):7167-7179

 

Jason LA, Unger ER, Dimitrakoff JD, Fagin AP, Houghton M, Cook DB, Marshall GD Jr, Klimas N, Snell C. (2012) Minimum data elements for research reports on CFS. Brain Behav. Immun. 26:401-6

 

Jiao Y, Leebens-Mack J, Ayyampalayam S, Bowers JE, McKain MR, McNeal J, Rolf M, Ruzicka DR, Wafula E, Wickett NJ, Wong GK et al. (2012). A genome triplication associated with early diversification of the core eudicots. Genome Biol. 13: R3

 

Johnson MT, … Wong GK. (2012) Evaluating methods for isolating total RNA and predicting the success of sequencing phylogenetically diverse plant transcriptomes. PLoS ONE.

 

Juran B, Hirschfield G, Invernizzi P, Atkinson E, Li Y, Xie G, Kosoy R, Ransom M, Sun Y, Bianchi I, Schlicht E, Lleo A, Coltescu C, Bernuzzi F, Podda M, Lammert C, Shigeta R, Chan L, Balschun T, Marconi M, Cusi D,   Mason AL, Myers L, Milkiewicz P, Odin J, Luketic V, Bacon B, Bodenheimer H, Liakina V, Vincent C, Levy C, Franke A, Gregersen P, Bossa F, Gershwin M, deAndrade D, Amos C, Lazaridis K, Seldin M, Siminovitch K. (2012) Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants. Human Mol. Gen. in press

 

Kruk T, Ratnam S, Preiksaitis JK, Lau A, Hatchette T, Horsman G, Van Caeseele P, Timmons B, Tipples G. (2012) Continuous Monitoring of the Performance of Rubella IgG and Hepatitis B Surface Antibody Assays Using Trueness Controls: Results of a Multicentre Trial.  Clinical and Vaccine Immunol. 19(10):1624-1632

 

Kumar D. (2012) Cellular immunity to CMV: Advancing to the next level. Detail Only Available. Ped. Transpl. 16: 6, 539-541. 3p. DOI: 10.1111/j.1399-3046.2011.01637.x

 

Lam WY, Tang JW, Chan PK. (2012) Identification of hepatitis B virus encoding/affecting microRNAs. Hong Kong Med J. Dec;18 Suppl 6:44-7

 

Lacasse JJ and Schang LM (2012) Herpes Simplex Virus 1 DNA Is in Unstable Nucleosomes throughout the Lytic Infection Cycle, and the Instability of the Nucleosomes Is Independent of DNA Replication. J Virol. 86 (20): 11827-11300

 

Lai, R and Ingham RJ. (2012). The pathobiology of the oncogenic tyrosine kinase NPM-ALK – a brief update. Therapeutic Advances in Hematology. accepted (Review Article)

 

Lee BE, Plitt SS, Jayaraman G, Chui L, Singh A, Preiksaitis JK. (2012) Use of quantitative HIV RNA detection for early diagnosis of HIV infection in infants and acute HIV infections in Alberta, Canada. J Clin Microbiol 50(2): 502-505

 

Li J, Hobman TC and Simmonds AJ. (2012) Gawky (Gw) is the Drosophila melanogaster GW182 homologue in Ten Year History of Progress in GW/P Body Research (eds. E.K.L. Chan and M. Fritzler) Springer, Netherlands

 

Lisboa LF, Tong Y, Kumar D, Pang XL, Asberg A, Hartmann A, Rollag H, Jardine AG, Pescovitz MD, Humar A. (2012) Analysis and clinical correlation of genetic variation in cytomegalovirus. Transpl Infect Dis. 2012 Apr;14(2):132-40

 

Lisboa LF, Preiksaitis JK, Humar A, Kumar D. (2012) Clinical utility of molecular surveillance for cytomegalovirus after antiviral prophylaxis in high-risk solid organ transplant recipients. Transpl. 92(9):1063-8

 

Lisboa LF, Tong Y, Kumar D, Pang XL, Asberg A, Hartmann A, Rollag H, Jardine AG, Pescovitz MD, Humar A. (2012) Analysis and clinical correlation of genetic variation in cytomegalovirus. Transpl Infect Dis. (2):132-40. doi: 10.1111/j.1399-3062.2011.00685.x. Epub 2011 Oct 14

 

Lisboa LF, Kumar D, Wilson LE, Humar A. (2012) Clinical utility of cytomegalovirus cell-mediated immunity in transplant recipients with cytomegalovirus viremia. Transplant. 93(2):195-200

 

Liu Y, Wang C, Li F, Shen S, Tyrrell DLJ, Le XC, Li XF. (2012) DNase-Mediated Single-Cycle Selection of Aptamers for Proteins Blotted on a Membrane.  Anal Chem. 18;84(18):7603-6

 

Magee WC and Evans, DH. (2012) The antiviral activity and mechanism of action of (S)-[3-hydroxy-2-(phosphonomethoxy) propyl] nucleosides (review). Antiviral Research 96(2):169-180. doi: 10.1016/j.antiviral.2012.08.010. [Epub ahead of print]

 

Maingat F, Polyak M, Paul AM, Vivithanaporn P, Noorbakhsh F, Aboucha S, Baker GB, Pearson K, Power C. (2012) The neurosteroid dehydroepiandrosterone sulfate suppresses neurovirulence produced by human and feline immunodeficiency viruses. FASEB J, in press

 

Manuel O, Husain S, Kumar D, Zayas C, Mawhorter S, Levi M, Kalpoe J, Kaul D, Schwartz B, Morris M, Ison M, Assi M, and Humar A. (2012) A prospective multicentre study of the assessment of cytomegalovirus specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients. Accepted Clin Infect Dis

 

McCombe, JA, Vivithanaporn P, Gill MJ, Power C.  (2012) Predictors of symptomatic HIV-associated neurocognitive disorders in universal health care. HIV Med; doi: 10.1111/j.1468-1293.2012.01043.x. [Epub ahead of print]

 

McElhaney JE, Zhou X, Talbot K, Soethout E, Bleackley RC, Granville D, Pawelec G. (2012) The unmet need in the elderly :  How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines.  Vaccine.  30(12) :2060-7

 

Mereniuk TR, Maranchuk R, Schindler A, Penner JC, Freschauf GK, Hegazy S,  Lai R, Foley E, and Weinfeld M. (2012) Genetic screening for synthetic lethal partners of polynucleotide kinase/phosphatase: potential for targeting SHP-1 depleted cancers. Cancer Res., 72:5934-5944; Published OnlineFirst September 7, 2012; doi:10.1158/0008-5472.CAN-12-0939

 

Montano-Loza AJ, Vargas-Vorackova F, Ma M, Bain VG, Burak K, Kumar T, Mason AL. (2012) Incidence and risk factors associated with de novo autoimmune hepatitis after liver transplantation. Liver International32;1426-33

 

Montgomery BC, Cortes HD, Burshtyn DN and Stafford JL. (2012) Channel catfish leukocyte immune-type receptor mediated inhibition of cellular cytotoxicity is facilitated by SHP-1-dependent and -independent mechanisms.    Developmental & Comparative Immunol. 37:151-163

 

Morris MI, Daly JS, Blumberg E, Kumar D, Sester M, Schluger N, Kim SH, Schwartz BS, Ison MG, Humar A, Singh N, Michaels M, Orlowski JP, Delmonico F, Pruett T, John GT, Kotton CN. (2012) Diagnosis and management of tuberculosis in transplant donors: a donor-derived infections consensus conference report. Am J Transplant. 12(9):2288-2300. doi: 10.1111/j.1600-6143.2012.04205.x. Epub 2012 Aug 6

 

Nestibo L, Lee BE, Fonseca K, Beirnes J, Johnson MM Sikora CA. (2012) Differentiating the wild from the attenuated during a measles outbreak.  Paediatr Child Health 17:e32-3

 

Okamoto T, Campbell S, Mehta N, Thibault J, Barry M, Huang D C and Kvansakul M.  (2012) Sheepox Virus SPPV14 Encodes a Bcl-2-like Cell Death Inhibitor that Counters a Distinct Set of Mammalian Pro-apoptotic Proteins.J  Virol., 86:11501-11511

 

Pang XL, Lee BE, Pabbaraju K, Gabos S, Craik S, Payment P, Neumann N. (2012) Pre-analytical and analytical procedures for the detection of enteric viruses and enterovirus in water samples. J Virol Methods. 2012 May 23. [Epub ahead of print]

 

Park J, Freitag SI, Young PG and Hobman TC. (2012) The karyopherin Sal3 is required for nuclear import of the core RNA interference pathway protein Rdp1. Traffic 13: 520-531

 

Pearson JD, Mohammed Z, Bacani JTC, Lai R, Ingham RJ. (2012). The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein. BMC Cancer. 12:229.

 

Pearson JD, Lee JKH, Bacani JTC, Lai R, Ingham RJ. (2012). NPM-ALK: the prototypic member of a family of oncogenic tyrosine kinases. J Signal Transduction. 22012:123253. Epub 2012 Jul 18. (Review Article)

 

Reinke SN, Resch L, Maingat F, Branton W, Jackson AC, Holt R, Slupsky C, Marrie T, Sykes BD, Power C. (2012) Metagenomic and metabolomic characterization of rabies encephalitis: New insights into the treatment of an ancient disease. J. Infect Dis, 2012 Aug 21. [Epub ahead of print]

 

Robinson JL, Vaudry WL, Forgie SE, Lee BE.  (2012) Prevention, Recognition and Management of Neonatal Herpes Simplex Virus Infections.  Expert Rev Anti Infect Ther (In press)

 

Rollag H, Asberg A, Ueland T, Hartmann A, Jardine AG, Humar A, Pescovitz MD, Bignamini AA, Aukrust P. (2012) Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients: Markers of Inflammation as Predictors of Outcome. Transplant. Epub ahead of print]

 

Shmulevitz M, Gujar SA, GyunAhn D, Mohamed, A.,Lee PWL. (2012). Reovirus variants with mutations in S1 and L2 genome segments exhibit enhanced virion infectivity and superior oncolysis. J. Virology, 86(13):7403-13

 

Shmulevitz M, Lee PW (2012). Exploring host factors that impact reovirus replication, dissemination, and reovirus-induced cell death in cancer versus normal cells in culture. Methods in Molecular Biology, volume 797, 163-76

 

Silva Jr. M, Humar A, Shapiro AMJ, Senior P, Hoschler K, Baluch A, Wilson LE, Kumar D. (2012) Humoral Immune Response following seasonal influenza vaccine in islet transplant recipients. Cell Transplant. [Epub ahead of print]

 

Singh AE, Guenette T, Gratrix J, Bergman J, Parker P, Anderson B, Plitt SS, Lee BE, Robinson JL. (2012) Seroreversion of Treponemal Tests in Infants meeting Canadian Surveillance Criteria for Confirmed Early Congenital Syphilis.  Ped Infect Dis J (In press)

 

Suen AYW and Baldwin TA. (2012) Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens. PNAS. 109(3): 893-898

 

Thomas B, Nishikawa S, Ito K, Chopra P, Sharma N, Evans DH, Tyrrell DLJ, Bathe OF, Rancourt DE. (2012) Peptide Vaccination is Superior to Genetic Vaccination using a Recombineered Bacteriophage Lambda Subunit Vaccine.    Vaccine. 1;30(6):998-1008

 

Toso C, Dupis-Lazeron E, Majino P, Berney T, Kneteman NM, Perneger T, Morel P, Mentha G, Combescure C. (2012) A model dropout assessment of candidates with or without hepatocellular carcinoma on a common liver transplant waiting list. Hepat.Hepat.. 56(1):149-56. Epub ahead of print  2012 Jun 18. 23 January 2012 [Epub ahead of print]

 

Toso C, Cader S, Mentha G, Meeberg G, Majno Pietro E, Morel P, Morard I, Giostra E, Berney T, Mentha G, . Kneteman N. (2012) Factors predicting survival afer post-transplant hepatocellular carcinoma recurrenc e.
J Hepatobiliary Pancreatic Sciences. 2012 June 19 [Epub ahead of print]

 

Tuszynski JA, Craddock TJ, Mane JY, Barakat K, Tseng CY, Gajewski M, Winter P, Alisaraie L, Patterson J, Carpenter E, … Wong GK. (2012) Modeling the yew tree tubulin and a comparison of its interaction with Paclitaxel to human tubulin. Pharm. Res. 29: 3007-3021

 

Unterweger D, Kitaoka M, Miyata ST, Bachmann V, Brooks J, Moloney J, Sosa O, Silva D, Duran-Gonzales J, Provenzano D, Pukatzki S. (2012) Constitutive type VI secretion system expression gives Vibrio cholerae intra- and interspecific competitive advantages. PLoS One 7 (10): e48320

 

Urbanowski MD and Hobman TC. (2012) The West Nile Virus Capsid Protein Blocks Apoptosis through a Phosphatidylinositol 3-kinase-dependent Mechanism. J. Virol. Oct 31. [Epub ahead of print]

 

Vanderven HA, Petkau K, Kieran, Ryan-Jean EE, Aldridge Jr. JA, Webster RG and Magor KE. (2012) Avian influenza rapidly induces antiviral genes in duck lung and intestine. Mol. Immunol.; 51: 316-324

 

Vasilenko NL, Snider M, Labiuk SL, Lobanov VA, Babiuk LA, and van Drunen Little-van den Hurk S. (2012) Bovine herpesvirus-1 VP8 interacts with DNA damage binding protein-1 (DDB1) and is monoubiquitinated during infection. Virus Res. 167(1): 56-66

 

Vivithanaporn P, Nelles K, DeBlock L, Newman SC, Gill MJ, Power C. (2012) Hepatitis C virus co-infection increases neurocognitive impairment severity and risk of death in treated HIV/AIDS. J Neurol Sci; 312(1-2):45-51

 

Wang Z, Hobson N, Galindo L, Zhu S, Shi D, McDill J, YangL, Hawkins S, Neutelings G, Datla R, … Wong GK, Wang J, Deyholos MK. (2012) The genome of flax (Linum usitatissimum) assembled de novo from short shotgun sequence reads. The Plant J. 72: 461-473

 

Weber B, Miyata S, Iwashkiw J, Stratilo C, Pukatzki S, Feldman M. (2012) Identification of a functional type VI secretion system in Acinetobacter baumannii (under review)

 

Williams KJ, Wilson E, Davidson CL, Aguilar OA, Fu, L, Carlyle JR, and Burshtyn DN. (2012) Poxvirus Infection-Associated Downregulation of C-Type Lectin-Related-b Prevents NK Cell Inhibition by NK Receptor Protein-1B.J Immunol. 188:4980-91

 

Wilkins C, Woodward J, Lau D, McFarlane N, Joyce MAJ, Tyrrell DLJ, Gale M Jr.  (2012) IFITM1 is a tight junction protein that inhibits hepatitis C virus entry.  Hepatol.  19 doi: 10.1002 (Epub ahead of print)

 

Wright AJ, Humar A, Gourishankar S, Bernard K, Kumar D. (2012) Severe Legionnaire’s disease caused by Legionella longbeachae in a long-term renal transplant patient: the importance of safe living strategies after transplantation. Transpl Infect Dis. 14(4):E30-3. doi: 10.1111/j.1399-3062.2012.00755.x. Epub 2012 Jun 11

 

Wu F, Zhang J, Wang P, Ye X, Jung K, Bone KM, Pearson JD, Ingham RJ, McMullen TP, Ma Y, Lai R. (2012). Identification of two novel phenotypically distinct breast cancer cell subsets based on Sox2 transcription activity. Cellular Signalling. 24(11):1989-98

 

Wu X, Robotham JM, Lee E, Daltn S, Kneteman NM, Gilbert DM, Tang H. (2012) Productive Hepatitis C virus Infection of Stem Cell—Derived hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentation. PLoS Pathog. 8(4):e1002617. Epub 2012 Apr 5

 

Xu Z and Hobman TC. (2012) The helicase activity of DDX56 is required for infectivity of West Nile virus particles. Virology 433: 226-235

 

Xu Z, Waeckerlin R, Urbanowski MD, van Marle G and Hobman TC. (2012) West Nile virus infection causes endocytosis of a specific subset of tight junction membrane proteins. PLoS One 7:e37886. Epub 2012 May 24

 

Yao Q, Fischer KP, Tyrrell DLJ, Gutfreund KS.  (2012) Genomic structure, molecular characterization and functional analysis of Pekin duck interleukin-10.  Developmental & Comparative Immuno. 38(1):30-43

 

Yao Q, Fischer KP, Tyrell DL and Gutfreund KS. (2012) cDNA cloning, genomic structure, molecular characterization and mRNA expression analysis of the Pekin duck interleukin-10 receptor 1. Int J Immunogenetics 39(1):55-67

 

Zhang J, Wang P, Wu F, Li M, Sharon D, Ingham RJ, Hitt M, McMullen TP, Lai R. (2012) Aberrant expression of the transcriptional factor Twist1 promotes invasiveness in ALK-positive anaplastic large cell lymphoma. Cellular Signalling. 24(4):852-8

 

Zhang J, Wang P, Dykstra M, Gelebart P, Williams D, Ingham R, Ekpe Adewuyi E, Lai R, McMullen T. (2012). Platelet Derived Growth Factor Receptor-α Promotes Lymphatic Metastases in Papillary Thyroid Cancer. J Pathology. 228(2):241-50

 

 

2011

Acharjee S, Zhu Y, Maingat F, Pardo C, Ballanyi K, Hollenberg M, Power C. (2011) Proteinase-activated receptor-1 mediates dorsal root ganglion neuronal degeneration in HIV/AIDS. Brain, 134 (Pt 11): 3209-21

 

Almekhlafi MA, Clark AW, Lucchinetti CF, Zhang Y, Power C, Bell RB. (2010) Neuromyelitis Optica with Extensive Active Brain Involvement: An Autopsy Study. Archives Neurol. 68(4):508-12

 

Altamirano-Diaz L, West L, Humar A, Ely L, Urschel S, Gubbay J, Crowcroft N, Kumar D. (2011) Early post-transplant vaccination with pandemic influenza A/H1N1 vaccine in pediatric heart transplant recipients. Pediat Transplant.  15: 172-5

 

Ang LS, Boivin WA, Williams SJ, Zhao H, Abraham T, McManus BM, Carmine-Simnen K, Bleackley RC and Granville DJ. (2011) Inhibition of extracellular granzyme B reduces abdominal aortic aneurysm rupture. Cell Death and Disease (in press)

 

Ang LS, Boivin WA, Williams SJ, Zhao H, Abraham T, McManus BM, Carmine-Simnen K, Bleackley RC and Granville DJ. (2011) Serpina3N attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm. Cell Death Dis. 2 e209

 

Antony JM, Deslauriers AM, Bhat RK, Ellestad KK, Power C. (2011) Human endogenous retroviruses and multiple sclerosis: Innocent bystanders or disease determinants? Biochim Biophys Acta. 1812(2):162-76

 

Asberg A, Jardine AG, Bignamini AA, Rollag H, Gahlemann CC, Humar A, Hartmann A. ( 2011) Response to letter about intensity of immunosuppressive therapy on outcome of treatment for CMV disease. Am J Transplant.  (5):1103-4.

 

Asthana S, Toso C, Meeberg G, Bigam DL, Mason A, Shapiro AMJ, Kneteman NM. (2011) The impact of sirolimus on Hepatitis C recurrence after liver transplantation. Can J Gastroenterol.  Jan; 25(1):28-34

 

Babiuk S,  Masic A, Graham J, Neufeld J,  van der Loop M,  Copps J, Berhane Y, Pasick J, Potter A, Babiuk LA, Weingartl H, Zhou Y.  (2011) An elastase-dependent attenuated heterologous swine influenza firus protects against pandemic H1N1 2009 influenza challenge in swine.  Vaccine.  29(17): 3118-3123

 

Baluch A, Humar A, Egli A, Gubbay J, Lisboa L, Wilson L, Kumar D. (2011) Long term immune responses to pandemic influenza A/H1N1 infection in solid organ transplant recipients. PLoS One. 2011;6(12):e28627. Epub 2011 Dec 14

 

Banadyga L, Lam S, Okamota T,  Kavansakul M, Huang D,  Barry M. (2011) Deerpox virus encodes an inhibitor of apoptosis that regulates Bak and Bax. J Virol. 85: 1922-1934

 

Barber MR, Guan Y, Magor KE, Peiris JS and Webster RG. (2011) The role of animal surveillance in influenza preparedness:the consequence of inapparent infection in ducks and pigs. Influenza and Other Respiratory Viruses. Suppl. 1:8-11

 

Bhat R, Ellestad KK, Wheatley BM, Warren RL, Holt RA, Power C. (2011)Brain Syncytin-1 is encoded by a single chromosomal locus in multiple sclerosis.  PLoS ONE, in press

 

Bell K,  Potter A, Babiuk L, Griebel P, Napper S.  (2011)  Stability, toxicity, and biological activity of host defense peptide BMAP28 and its inversed and retro-inversed isomers.  Biopolymers.  96: 14-24

 

Bhat R, Ellestad KK, Wheatley BM, Warren RL, Holt RA, Power C. (2011) Brain Syncytin-1 is encoded by a single chromosomal locus in multiple sclerosis.  PLoS ONE, 6(4): e19176

 

Caddy S, Lee BE, Sutherland K, Robinson J, Plitt S, Read, Singh AE.  (2011) Pregnancy and Neonatal Outcomes of Women with Reactive Syphilis Serology in Alberta, 2002-06. J Obstet Gynaecol Can. 33:453-9

 

Ciesek S, von Hahn T, Colpitts CC, Schang LM, Friesland M, Steinmann J, Manns MP, Ott M, Wedemeyer H, Meuleman P, Pietschmann T, and Steinmann E (2011) The green tea polyphenol epigallocatechin-3-gallate (EGCG) inhibits 1 hepatitis C virus (HCV) entry. Hepatol. 54(6):1947-1955

 

Conn K, Hendzel M, and Schang LM (2011) Core histones H2B and H4 are mobilized during infection with herpes simplex virus type 1 (HSV-1). J Virol. 85 (24):13234-52

 

Cooper C, Kanters S, Klein M, Chaudhury P, Marotta P, Wong P, Kneteman N, Mills E. (2011) Liver transplant outcomes in HIV-infected patients: a systematic review and meta-analysis with synthetic cohort. AIDS   Mar27: 25(6):777-787

 

Cooper C, Thorne A, Klein M, Conway B, Boivin G, Haase D, Shafran S, Zubyk W, Singer J, Halperin S, Walmsley S; CIHR Canadian HIV Trials Network Influenza Vaccine Research Group. (2011) Immunogenicity is not improved by increased antigen dose or booster dosing of seasonal influenza vaccine in a randomized trial of HIV infected adults. PLoS One 6(3)e17758

 

Couturier MR, Lee B, Zelyas N, Chui L. (2011) Shiga-toxigenic Escherichia coli detection in stool samples screened for viral gastroenteritis in Alberta, Canada.  J Clin Microbiol. 49:574-8. Epub 2010 Dec 8.

 

Dauber B, Pelletier J, Smiley JR. (2011) The HSV-1 vhs protein enhances translation of viral true late mRNAs and virus production in a cell-type dependent manner.  J Virol. 85: 5363-5373

 

Deslauriers A, Afkhami-Goli A, Paul A , Bhat R, Acharjee S, Ellestad K , Noorbakhsh F, Michalak M, Power C. (2011) Neuroinflammation and endoplasmic reticulum stress are co-regulated by crocin to prevent demyelination and neurodegeneration. J. Immunol.; Nov 1; 187(9): 4788-99

 

Drews SJ, Pabbaraju K, Wong S, Tokaryka KL, May-Hadford J, Lee B, Tellier R, Louie M.  (2011) Surveillance of autopsy cases for the D222G substitutions in the haemagglutinin (HA) protein of Pandemic (H1N1) 2009 virus in Alberta, Canada.  Clin. Microbiol. & Infect. 17(4):582-4 (Epub 2010)

 

Fagan K, Barry M. (2011) A vaccinia virus deletion mutant reveals the presence of additional inhibitors of NF-κB.  J Virol. 85:883-894

 

Fleming-Canepa X, Brusnyk C, Aldridge JR, Ross KL, Moon D, Wang D, Xia J, Barber MRW, Webster RG, Magor KE. (2011) Expression of duck CCL19 and CCL21 and CCR7 receptor in lymphoid tissue and influenza-infected tissues. Mol. Immunol. 48, 1950-1957

 

Forgie SE, Keenliside J, Wilkinson C, Webby R, Lu P, Sorensen O, Fonseca K, Barman S, Rubrum A, Stigger E, Marrie TJ, Marshall F, Spady DW,  Hu J, Loeb M, Russell ML, Babiuk LA. (2011) Swine Outbreak of Pandemic Influenza A Virus on a Canadian Research Farm Supports Human-to-Swine Transmission. Clin Infect Dis. 52:10-8

 

Fries P,  Popowych YI,  Guan LL, Beskorwayne TI,  Potter A, Babiuk LA, Griebel PJ. (2011)  Muscosal dendritic cell subpopulations in the small intestine of newborn calves.  Dev Comp Immunol.   35: 1040-1051

 

Fu L, Hazes B, Burshtyn DN. (2011) The first Ig-domain of KIR3DL1 contacts MHC-I at a secondary site. J  Immunol. 187:1816-25  July 11 (Epub ahead of print)

 

Gala-Lopez BL, Senior PA, Koh A, Kashkoush SM, Kawahara T, Kin T, Humar A*, Shapiro AM* (joint-senior authors) (2011) Late Cytomegalovirus Transmission and Impact of T-Depletion in Clinical Islet Transplantation. Am J Transplant. (12):2708-14

 

Garlapati S, Eng NF, Kiros TG, Kindrachuk J, Mutwiri GK, Hancock RE, Halperin SA, Potter AA, Babiuk LA, Gerdts V. (2011) Immunization with PCEP microparticles containing pertussis toxoid, CpG ODN and a synthetic innate defense regulator peptide induces protective immunity against pertussis. Vaccine. 29(38), 6540-6548

 

Gracia A, Polewicz M, Halperin SA, Hancock RE,  Potter AA, Babiuk LA, Gerdts V. (2011)  Antibody responses in adult and neonatal BALB/c mice to immunization with novel Bordetella pertussis vaccine formulations.  Vaccine.  29(8): 1595-1604

 

Gerdts,V, Mutwiri G, Babiuk LA, Potter A, Napper S, vand den Hurk S, Wilson H, and Aura, G. (2011) In 1st Edition: Vaccinology: Principles and Practice. Editors Morrow, Sheikh, Davies & Schmidt.

 

Guntermann S, Foley E. (2011) The protein Dredd is an essential component of the c-Jun N-terminal Kinase pathway in the Drosophila immune response.. J  Biol.Chem., 286(35):30284-94

 

Haile Y, Pasychniyk D, Turner D, Bleackley RC, Giuliani F. (2011) CD4+CD25+CD127dimFoxp3+T cells are cytotoxic for human neurons. J. Leukoc Biol. 89(6) : 927-34

 

Argonaute Proteins: Methods and Protocols (2011) in Methods in Molecular Biology volume 725: (eds. Hobman TC and Duchaine TF) Springer-Verlag, New York, NY

 

Hong C, Duit S, Jalonen P, Out R, Scheer L, Boyadjian R, Rodenburg K, Foley E, Korhonen L, Lindholm D, Nimph J, van Berkel T, Tontonoz P,  Zelcer N. (2010) The E3-ubiquitin ligase IDOL induces the degradation of the low-density lipoprotein receptor family members VLDLR and ApoER2. J Biol Chem. 285(26): 19720-6

 

Houghton M. (2011) Prospects for prophylactic and therapeutic vaccines against the hepatitis C viruses. Immunol Rev. Jan; 239(1):99-108

 

Humar A; IMPACT Investigators Steering Committee, Peeters P, Abramowicz D, Humar A, Lebranchu Y, Hauser I, Jardine A, Limaye AP, Vincenti F, Punch JD, Blumberg E. (2011) Response to questions regarding the design and results of the IMPACT trial. Am J Transplant. 11(1):177-8.

 

Ilkow C, Goping IS,  Hobman TC. (2011) The Rubella Virus Capsid is an Anti-Apoptotic Protein that Attenuates the Pore-Forming Ability of Bax.  PLoS Pathogens 7: ppat.1001291

 

Julien, O, Beadle JR, Magee WC, Chatterjee S, Hostetler KY,  Evans DH, Sykes BD. (2011) Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir.  JACS 133: 2264-2274

 

Kassam F, Lee BE, Damji KF.  (2011) Case Report: Concurrent Endophthalmitis and Orbital Cellulitis in a Child with Congenital Glaucoma.  Digital J Opththalmology Vol 17, No 4. http://www.djo.harvard.edu/site.php?url=/physicians/cr/1591

 

Kapiriri L, Lavery JV, Singer PA, Mshinda H, Babiuk LA, and Daar AS. (2011) The case for conducting first-in-human (phase 0 and phase 1) clinical trials in low and middle income countries. BMC Public Health. 11: 811

 

Kawahara T, Kin T, Kashkoush S, Gala Lopez B, Bigam DL, Kneteman NM, Koh A, Senior PA, Shapiro AMJ. (2011) Protal Vein Thrombosis in a Potentially Preventable Complication in Clinical Islet Transplantation. AJ Transpl. 11(12); 2700-2707. 29 August 2011 [E-pub ahead of print]

 

Kindrachuk J, Scruten E, Attah-Poku S, Bell K, Potter A, Babiuk LA., Griebel P, Napper S. (2011) Stability, toxicity, and biological activity of host defense peptide BMAP28 and its inversed and retro-inversed isomers. Biopolymers. 96: 14-24

 

Kiros TG, van Kessel J, Babiuk LA, and Gerdts V. (2011) Induction, regulation and physiological role of IL-17 secreting helper T-cells isolated from PBMC and lung lymphocytes of young pigs. Vet Immunol & Immunopath. 144(3-4), 448-454

 

Kitaoka M, Miyata ST, Unterweger D, Pukatzki S. (2011) Antibiotic resistance mechanisms of Vibrio cholerae. JMed Microbiol 60 (Pt 4): 397-407

 

Kneteman N, Livraghi T, Madoff D, de Santibanez E, Kew M. (2011) Tools for monitoring patients with hepatocellular carcinoma on the waiting list and after liver transplantation. Liver Transpl. Suppl 2:S117-27

 

Kneteman NM, Lewis J, Dibben C, Douglas D, Nourbakhsh M, Tyrrell DL, Lund G. (2012) The Impact of Calcineurin Inhibitors with or without interferon on HCV virus titers in a Chimeric Mouse model of HCV Infection. Liver Transpl. 18(1):38-44. 2011 Aug 11.[Epub ahead of print]

 

Kumar D, Blumberg EA, Danziger-Isakov L, Kotton CN, Halasa NB, Ison MG, Avery RK, Green M, Allen UD, Edwards KM, Miller G, Michaels MG; AST Infectious Diseases Community of Practice. (2011) Influenza vaccination in the organ transplant recipient: review and summary recommendations. Am J Transplant. (10):2020-30. doi: 10.1111/j.1600-6143.2011.03753.x. Review

 

Kumar D, Campbell P, Humar A. (2011) Donor-specific alloantibody upregulation after influenza vaccination in transplant recipients. Am J Transplant. 11(11):2538

 

Kumar D, Danziger-Isakov L (2011) Immunization against influenza: a balancing act. Am J Transplant. 2011 11(8):1561-2. doi: 10.1111/j.1600-6143.2011.03605.x. Epub 2011 Jun 14

 

Landi A, Babiuk LA, van Drunen Littel-van den Hurk S. (2011) Dendritic cells matured by a prostaglandid E2-containing cocktail can produce high levels of IL-12p70 and are more mature and Th1-biased than dendritic cells treated with TNF-α or LPS. Immunobiol. 216(6): 649-662

 

Labrecque N, Baldwin T, Lesage S. (2011) Molecular and genetic parameters defining T-cell clonal selection. Immunol. & Cell Biol. 89(1): 16-26

 

Lee BE, Mukhi SN, May-Hadford J, Plitt S, Drews SJ. (2011) Determination of the relative economic impact of different molecular-based laboratory algorithms for respiratory viral pathogen detection, including Pandemic (H1N1) using a secure web based platform.  Virol J  8:1, 277-287. 11p. DOI: 10.1186/1743-422X-8-277

 

Lee BE, Plitt S, Fenton J, Preiksaitis JK, Singh AE.  (2011) Rapid HIV tests in acute care settings in an area of low HIV prevalence in Canada.  J Virol Methods.  172(1-2):66-71

 

Li NL, Davidson CE, Humar A and Burshtyn DN. (2011) Modulation of the inhibitory receptor leukocyte Ig-like receptor 1 on human natural killer cells.  Frontiers in NK Cell Biology, available on line Sept 06, 2011

 

Lisboa LF, Asberg A, Kumar D, Pang X, Hartmann A, Preiksaitis JK, Pescovitz MD, Rollag H, Jardine AG, Humar A. (2011) The clinical utility of whole blood versus plasma cytomegalovirus viral load assays for monitoring therapeutic response. Transplant.  91: 231-236

 

Lisboa LF, Åsberg A, Kumar D, Pang X, Hartmann A, Preiksaitis JK, Pescovitz MD, Rollag H, Jardine AG, Humar A. (2011) The Clinical Utility of Whole Blood vs. Plasma CMV Viral Loads Assays for Monitoring Therapeutic Response.  Transpl., 15(2): 172-5

 

Lisboa LF, Preiksaitis JK, Humar A, Kumar D.  (2011) Clinical utility of molecular surveillance for cytomegalovirus after antiviral prophylaxis in high-risk solid organ transplant patients. Transplant. 92(9):1063-8.

 

Ma B, Kane KP. (2011) Recognition of class I MHC by a rat Ly49 NK cell receptor is dependent on the identity of the P2 anchor amino acid of bound peptide. J. Immunol. 187:3267-3276; published ahead of print August 12, 2011, doi:10.4049/jimmunol.1002809

 

MacIntyre D, Miyata S T, Kitaoka M, Pukatzki S. (2011) The Vibrio cholerae type VI secretion system displays antimicrobial activity. PNAS 107: 19520-19524. 2010. (discussed in Nature Reviews Microbiology [Sanchez, C.: Vibrio cholerae beats the competition. NRM 9: 6. 2011])

 

Mader JS, Hancock REW, Bleackley RC. (2011) The human cathelicidin, LL-37, inducesgranzyme-mediated apoptosis in regulatory T cells.  J. Immunother. 34(3) : 229-35

 

Mader JS, Marcet-Palacios M, Hancock REW, Bleackley RC.  (2011) The human cathelicidin, LL-37, induces granzyme-mediated apoptosis in cytotoxic T lymphocytes.  Exp Cell Res. 317(4) : 531-8

 

Magee WC, Valiaeva N, Beadle JR, Richman DD, Hostetler KY, and Evans DH. (2011) Inhibition of HIV-1 by octadecyloxyethyl esters of (S)-[3-Hydroxy-2-(phosphonomethoxy)propyl] nucleosides and evaluation of their mechanism of action.  Antiviral Agents & Chemotherapy 55, 5063-72

 

Magor KE. (2011) Immunoglobulin genetics and antibody responses to influenza in ducks. Developmental and Comparative Immunol.  Mar. 4 Epub, ahead of print. Review

 

Noorbakhsh F, Ellestad K, Maingat F, Warren K, Han M, Steinman L, Baker GB, Power C. (2011) Impaired neurosteroid synthesis in multiple sclerosis. Brain, 134 (9): 2703-2721

 

Maingat F, Halloran B, Acharjee S, van Marle G, Church D, Gill MJ, Uwiera RRE, Cohen EA, Meddings J, Madsen K, Power C.  Inflammation and intestinal epithelial cell injury in AIDS enteropathy: a role for endoplasmic reticulum stress. FASEB J, 25(7):2211-20

 

Manuel O, Humar A, Berutto C, Ely L, Giulieri S, Lien D, Meylan PR, Weinkauf J, Pascual M, Nador R, Aubert JD, Kumar D. (2011) Low-dose intradermal versus intramuscular trivalent inactivated seasonal influenza vaccine in lung transplant recipients. J Heart Lung Transplant.  Jun; 30(6):679-84

 

Mackenzie- Dyck S, Attah-Poku S, Juillard B, Babiuk LA, Hurk SV. (2011) The synthetic peptides bovine enteric β-defensin (EBD), bovine neutrophil β-defensin (NDBN) 9 and BNBD 3 are chemotactic for immature bovine dendritic cells. Vet Immunol Immunopathol. 15;143(1-2):87-107. Epub 2011 Jun 2

 

Marcet-Palacios M., Duggan BL, Shostak I, Barry M, Wilkins JA, Akiko A, Sonenberg N and Bleackley RC (2011). Granzyme B inhibits translation of viral proteins through proteolytic cleavage of the eukaryotic initiation factor 4 gamma 3. PLOS Pathogens 7(12):e1002447. Epub 2011 Dec 15

 

Mason A. (2011) Primary Biliary Cirrhosis. Chapter in 6th Edition of First Principles of Gastroenterology. B. Sis. Editors: E. A. Shaffner, A. B. R. Thomson, in press

 

Mason A. (2011) The evidence supports a viral etiology of primary biliary cirrhosis. Controversies in Hepatology. J Hepatol, 54: 6, 1312-1314

 

Mason A, Gilady S, Mackey J.  (2011) Mouse mammary tumor virus in human breast cancer: red herring or smoking gun? AJ Patho. 179:1588-1590

 

McCombe JA, Acharjee S, Gill JM, Power C.  (2011) Viral and host genetic factors in the neuropathogenesis of human immunodeficiency virus-1 infection. Ed. Gendelman HE. The Neurology of AIDS, 3 ed. Oxford University Press. New York, New York

 

Mattison K, Grudeski E, Auk B, Brassard J, Charest H, Dust K, Gubbay J, Hatchette TF, Houde A, Jean J, Jones T, Lee BE, Mamiya H, McDonald R, Mykytczuk O, Pang X, Petrich A, Plante D, Ritchie G, Wong J, Booth TF. (2011) Analytical performance of norovirus real-time RT-PCR detection protocols in Canadian laboratories.  J Clin Virol. 50:109-13

 

Merani S, Majno P, Kneteman NM, Berney T, Morel P, Mentha G, Toso C. (2011)The impact of waiting list alpha-fetoprotein changes on the outcome of liver transplant for hepatocellular carcinoma. J Hepatol  55(4);814-9 Epub: Feb 17

 

Meunier JC, Gottwein JM, Houghton M, Russell RS, Emerson SU, Bukh J, Purcell RH. (2011) Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus. J Infect Dis; 204 (8): 1186-90

 

Miyata ST, Kitaoka M, Brooks TM, McAuley SB, Pukatzki S. (2011) Vibrio cholerae requires thetype VI secretion system virulence factor VasX to kill Dictyostelium discoideum. Infect & Immunity 79: 2941-2949

 

Montano-Loza AJ, Mason AL (2011) Can anti-retroviral therapy help patients with primary biliary cirrhosis. Medicina Universitaria, 13 :101-7

 

Montano-Loza AJ, Myers RP, Mason AL. (2011) Lessons learned from liver transplantation with the Canadians First Nations. Can. J.Gastroenterol. 25:305-306

 

Mukhi SN, Stuart-Chester TL, Klaver-Kibria JDA, Nowicki DL, Whitlock ML, Mahmud SM, Louie M, Lee BE.  (2011) Innovative technology for web-based data management during an outbreak.  Online J Public Health Informatics. Vol 3, No 1. http://ojphi.org/htbin/cgiwrap/bin/ojs/index.php/ojphi/article/view/3514/3010

 

Mutwiri G, Gerdts V, van Drunen Littel-van den Hurk S, Auray G, Eng N, Garlapati S, Babiuk LA, Potter A. (2011) Combination adjuvants: the next generation of adjuvants? Expert Rev Vaccines.10:95-107.

 

Na H, Acharjee S, Jones G, Vivithanaporn P, Noorbakhsh F, Barsby N, Maingat F, Ballanyi K, Pardo C, Cohen E, Power C.  (2011) In vivo HIV-1 Vpr molecular diversity: domain- and residue- dependent neuroimmunity and neurodegeneration. Retrovirol,  8:44

 

Pabbaraju K, Wong S, Lee B, Tellier R, Fonseca K, Louie M, Drews SJ. (2011) Comparison of a singleplex real-time RT-PCR assay and multiplex respiratory virus panel assay for detection of influenza A in respiratory specimens.  Influenza and Other Respiratory Viruses. Influenza Other Respi Viruses. 5(2):99-103

 

Pang XL, Cao M, Zhang M, Lee B. (2011)  Increased sensitivity for various rotavirus genotypes in stool specimens by amending three mismatched nucleotides in the forward primer of a real-time RT-PCR assay.  J Virol Methods  172:85-87

 

Pan D, Pan L, Hill R, Marcato P, Shmulevitz M, Vassilev LT, Lee PWL (2011). Stabilization of p53 enhances reovirus-induced apoptosis and virus spread through p53-dependent NF-kb activation. Br J Cancer, 105(7):1012-22

 

Pare JM, Lopez-Orozco J, Hobman TC. (2011) Live Cell Imaging of Argonaute Proteins in Mammalian Cells. Methods Mol Biol. 725:161-172

 

Pare JM, Lopez-Orozco J, Hobman TC. (2011) MicroRNA-binding is required for recruitment of human Argonaute2 to Stress Granules and P-bodies. Biochem Biophys Res Com 414: 259-64

 

Parker HR and Hobman TC. (2011) Cytoplasmic RNA Domains, in Cellular Domains (ed I. R. Nabi), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118015759.ch25

 

Pearson JD, Lee JK, Bacani JT, Lai R, Ingham RJ. (2011) NPM-ALK and the JunB transcription factor regulate the expression of cytotoxic molecules in ALK-positive, anaplastic large cell lymphoma. Int J Clin Exp Pathol. Jan 30;4(2):124-33

 

Pham T, Richard J, Gerard F, Power C, Cohen E. (2011) Modulation of NKG2D-Mediated Cytotoxic Functions of Natural Killer Cells by Viral Protein R (Vpr) from HIV-1 Primary Isolates. J. Virol, 85(23): 12254-61

 

Ping J, Keleta L, Forbes NE, Dankar S, Stecho W, Tyler S, Zhou Y, Babiuk LA, Weingartl Hl, Halpin RA, Boyne A, Bera J, Hostetler J, Fedorova NB, Proudfoot K, Katzel DA, Stockwell TB, Ghedin E, Spiro DJ, Brown EG. (2011) Genomic and protein structural maps of adaptive evolution of human influenza a virus to increase virulence in the mouse. PLoS One. 6: e21740

 

Polewicz M, Gracia Al, Buchanan R, Strom S, Halperin SA, Potter AA, Babiuk LA, and Gerdts V. (2011) Influence of maternal antibodies on active pertussis toxoid immunization of neonatal mice and piglets. Vaccine. 29(44), 7718-7726

 

Power C, Hui E, Vivithanaporn P, Acharjee S, Polyak M. (2011) Delineating HIV-associated neurocognitive disorders using transgenic models: The neuropathogenic actions of Vpr. JNIP; 7(2), 319-31

 

Qin L, Upton C, Hazes B, and Evans DH. (2011) Genomic analysis of the vaccinia virus strain variants found in Dryvax vaccine.  J. Virol. 85:13049-13060

 

Ramji QA, Bayrack K, Arefanian H, Marcet-Palacios M, Bleackley RC, Rajotte RV and Rayat GR. (2011) Protection of porcine islet xenografts in mice using sertoli cells and monoclonal antibodies. Transpl. 92(12) :1309-15

 

Rintoul JL, Wang J, Gammon DB, van Buuren NJ, Garson K, Barry M, Evans DH and Bell JC. (2011) A selectable and excisable marker system for the rapid creation of recombinant poxviruses. PLoS One, 6(9):e24643

 

Robertson LK and Ostergaard HL  (2011) Paxillin Associates with the Microtubule Cytoskeleton and the Immunological Synapse of CTL through its LD Domains and Contributes to Microtubule Organizing Center Reorientation.  J. Immunol. 187:5824-5833

 

Ruma Mukerjee J, Chang R, Del Valle L, Bagashev A, Gayed M, Lyde R, Hawkins B, Brailoiu E, Cohen E, Power C, Azizi AS, Gelman B, Sawaya B. (2011) Deregulation of microRNAs by HIV-1 Vpr leads to the development of neurocognitive disorders. J. Biol. Chem.; 286(40):34976-85

 

Samadi, N, Bekele, R, Goping, IS, Schang, LM and Brindley, D (2011) “Lysophosphat-idate Induces Chemo-resistance by Releasing Breast Cancer Cells from Taxol-induced Mitotic Arrest” PLoS ONE 6(5): e20608-17344

 

Schang LM. (2011) Cellular protein kinases as antiviral targets.  pp305-347 in “Protein Kinases as Drug Targets” (Drs. Bert Klebl, Gerhard Mueller, and Michael Hamacher Editors), Methods and Principles in Medicinal Chemistry (Volume 49) Wiley-VCH, Verlag & Co., KGaA, Weinheim, Germany

 

Sawhney S, Montano-Loza AJ, Salat P, McCarthy M, Kneteman N, Meza-Junco J, Owen R. (2011) Transarterial chemoemboilizaton in patients with hepatocellular carcinoma: Predictors of survival. Can J Gastroenterol.  25(8):436-32

 

Singh AE, Plitt SS, Osiowy C, Surynicz K, Kouadjo E, Preiksaitis J, Lee BE.  (2011) Factors Associated with Vaccine Failure and Vertical Transmission of Hepatitis B among a Cohort of Canadian Mothers and Infants.  J Viral Hepatitis 18:468-73 (Epub 2010)

 

Stamataki Z, Coates S,Abrignani S, Houghton M, McKeating J. (2011) .. Immunization of human volunteers with Hepatitis C virus envelope glycoproteins elicits antibodies that cross-neutralize heterologous virus strains (2011) J Infect Dis; 204(5):811-813

 

Steffen I, Tyrrell DLJ, Stein E, Montalvo L, Zhou Y, Tang S, Jia H, Switzer W. Lee TH, KewelRamani V, Hockman D, Santer D, Logan M, Landi A, Law J, Houghton M, and Simmons G. (2011) No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome.  Plos One. 6(11):e27870.  Epub 2011 Nov 17

 

St-Pierre J, Lysechko TL, Ostergaard HL.  (2011) Hypophosphorylated and inactive Pyk2 associates with paxillin at the microtubule organizing center in hematopoietic cells.  Cell Signal. Apr; 23(4):718-30

 

Sutendra G, Dromparis P, Bonnet S, Haromy A, McMurtry MS, Bleackley RC and Michelakis ED. (2011) Pyruvate dehydrogenase inhibiton by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension. J. Mol. Med. (Berl) 89(8):771-783

 

Thangavelu G, Parkman JC, Ewen CL, Uwiera RRE, Baldwin TA, Anderson CC. (2011) Programmed death-1 is Required for Systemic Self-tolerance in Newly Generated T Cells During the Establishment of Immune Homeostasis. J Autoimmunity. 36(3-4):301-312

 

Thiery J, Keefe D, Boulant S, Boucrot E, Walch M, Martinvalet D, Goping IS, Bleackley RC, Kirchhausen T and Lieberman J.  (2011) Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells.  Nature Immunol  12(8):770-777

 

Toso C, Cader S, Mentha G, Meeberg G, Majno Pietro E, Morel P, Morard I, Giostra E, Berney T, Mentha G, . Kneteman N. (2012) Factors predicting survival afer post-transplant hepatocellular carcinoma recurrenc e. J Hepatobiliary Pancreatic Sci. [Epub ahead of print]

 

Tracey B.  (2011 June) HCV’s mighty mouse.  Commentary by Tyrrell DLScience Business Exchange 16:4/24:1-4.

 

Van de Vosse  DW, Wan Y, Wozniak RW, Aitchison JD. (2011) Role of the nuclear envelope on genome organization and gene expression.  Wiley Interdisciplinary Reviews: Systems Biol. & Med. 2:147-66

 

Vivithanaporn P, Gill MJ, Power C. (2011) Impact of current antiretroviral therapies on neuroAIDS. Expert Rev Anti Infect Ther.  9(4): 371-4

 

Wagner MJ,  Smiley J.R.  (2011) Herpes simplex virus requires VP11/12 to activate src-family kinase- PI 3 kinase –Akt signaling.  J Virol. 85: 2803-2812

 

Wang P, Wu F, Zhang J, McMullen T, Young LC, Ingham RJ, Li L, Lai R. (2011) Serine phosphorylation of NPM-ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential. Carcinogenesis.32(2):146-53. Epub 2010 Nov 2

 

Woods MW, Kelly JN, Hattiman C J, Tong JGK, Xu LS, Coleman MD, Quest GR, Smiley JR and Barr SD. (2011) Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag. Retrovirol. 8: 95

 

Wu X, Robotham JM, Lee E, Daltn S, Kneteman NM, Gilbert DM, Tang H. (2012) Productive Hepatitis C virus Infection of Stem Cell—Derived hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentation. PLoS Pathog. 8(4):e1002617. Epub 2012 Apr 5.

 

Xu Z, Anderson R,  Hobman, TC. (2011) The nucleolar helicase DDX56 is required for assembly of infectious West Nile virions. J Virology. 85: 5571-5580

 

Yao Q, Fischer KP, Tyrrell DLJ, and Gutfreund KS.  (Nov. 2011) cDNA cloning, genomic structure, molecular characterization and mRNA expression analysis of the Pekin duck interleukin-10 receptor 1.  International Journal of Immunogenetics. 39:55-67. doi: 10.1111/j.1744-313X.2011.01058.x

 

Zamora MR, Budev M, Rolfe M, Gottlieb J, Humar A, Devincenzo J, Vaishnaw A, Cehelsky J, Albert G, Nochur S, Gollob JA, Glanville AR. (2011) RNA interference therapy in lung transplant patients infected with respiratory syncytial virus. J Respir Crit Care Med. 183: 531-8

 

Zhang G, Chen M, Graham D, Subsin B, McDougall C, Kneteman M, Swain M, Trauner M, Wrzesinski S, Flavell R, Wasilenko S, Mason A. (2011) Mouse mammary tumor virus in anti-mitochondrial antibody producing mouse models . J Hepatol., 55: 4, 876-884

 

Zhi L, Chen C, Pang X, Uludag H, Jiang H. (2011) Synergistic effect of recombinant human bone morphogenic protein-7 and osteogenic differentiation medium on human bone-marrow-derived mesenchymal stem cells in vitro. Int Orthop. Apr 13. [Epub ahead of print]

 

 

2010

Acharjee S, Noorbakhsh F, Stemkowski PL, Olechowski C, Cohen EA, Ballanyi K, Kerr B, Pardo C, Smith PA, Power C.  (2010) HIV-1 viral protein R causes in vivo peripheral nervous system injury associated with neuropathic pain.  FASEB J. 24(11): 4343-53

 

Al Aklabi MM, Weinkauf JG, Humar A, Ghorpade N. (2010) Successful bilateral lung transplantation in a patient with end-stage lung disease and positive novel influenza virus (H1N1). J Heart Lung Transplant.  29: 898-9

 

Allam N, Al Saghier M, El Sheikh Y, Al Sofayan M, Khalof H, Al Sebayel M, Halemy A, Kamel Y, Al Jedai A, Abdel-Dayem H, Kneteman NM, Al Saghier A, Al Hamoudi W, Abdo AA. (2010) Clinical Outcomes for Saudi and Egyptian Patients Receiving Deceased Donor Liver Transplantation in China. AJ Transplant  10:1834-1841

 

Asberg A, Jardine AG, Bignamini AA, Rollag H, Pescovitz MD, Gahlemann CC, Humar A, Hartmann A, VICTOR Study Group. (2010) Effects of the intensity of immunosuppressive therapy on outcome of treatment for CMV disease in organ transplant recipients. Am J Transplant.  10: 1881-8

 

Asthana S, Maguire C, Lou L, Meier M, Bain V, Townsend R, Lien D, Bigam D, Kneteman N, Shapiro AM. (2010) Successful resolution of severe hepatopulmonary syndrome following liver transplantation. Transpl Int. 23(4):432-5. 2009 Nov 18 [Epub ahead of print].

 

Auray G, Facci  MR, van Kellel  J, Buchanan R, Babiuk LA, Gerdts V.  (2010)  Differential activation and maturation of two porcine DC populations following TLR ligand stimulation.  Mol Immunol. 47: 2103-2111

 

Avery R, Clauss H, Danziger-Isakov L, Davis J, Doucette K, van Duin D, Fishman J, Gunseren F, Humar A, Husain S, Isada C, Julian K, Kaul D, Kumar D, Martin S, Michaels M, Morris M, Silveira F, Subramanian A.  (2010) Recommended curriculum for subspecialty training in transplant infectious disease on behalf of the American Society of Transplantation Infectious Diseases Community of Practice Educational Initiatives Working Group. Transpl Infect Dis., 12(3):190-4

 

Banadyga L, Barry M. (2010) A Matter of Life and Death: Viruses Inhibit Cell Suicide. Biology on the Cutting Edge. Concepts Issues and Canadian Research Around the Globe. Editors S.L. Gilles and S. Hewitt. Pearson Canada Inc, Toronto, Ontario, Canada, pg. 153-157

 

Barber MRW (nee MacDonald), Aldridge JR , Webster RG, Magor KE.  (2010) Association of RIG-I with innate immunity of ducks to influenza. PNA Sciences, U.S.A., 107(13):5913-8

 

Barry M, vanBuuren N, Burles K, Mottet K, Wang Q, Teale A. (2010) Poxvirus Exploitation of the Ubiquitin-Proteasome System. Viruses 2:2356-2380

 

Blais DR, Lyn RK, Joyce MA, Rouleau Y, Steenbergen R, Barsby N, Zhu LF, Pegoraro AF,  Stolow A, Tyrrell DLJ, Pezacki JP.  (2010)  Activity-based protein profiling identifies a host enzyme carboxylesterase 1 that is differentially active during hepatitis C replication.  J Biol. Chem.   285(3):25602-12

 

Booth JS,  Arsenault R,  Napper S,  Griebel PJ,  Potter AA, Babiuk LA, Mutwiri  GK. (2010) TLR9 signaling failure renders Peyer’s Patch regulatory B cells unresponsive to stimulation with CpG Oligodeoxnucleotides. J Innate Immun. 2: 483-94

 

Booth JS, Buza JJ, Potter A, Babiuk LA, Mutwiri GK. (2010) Co-stimulation with TLR7/8 and TLR9 agonists induce down-regulation of innate immune responses in sheep blood mononuclear and B Cells. Dev Comp Immunol. 34: 572-578

 

Bow EJ, Evans G, Fuller J, Laverdière M, Rotstein C, Rennie R, Shafran SD, Sheppard D, Carle S, Phillips P, Vinh DC. (2010) Canadian clinical practice guidelines for invasive candidiasis in adults. Can J Infect Dis Med Microbiol 21(4):e122-50

 

Burak K, Kneteman NM. (2010) An Evidence-Based Mulitdisciplinary Approach to the Management of Hepatocelllar Carcinoma (HCC): The Alberta HCC Algorithm. Can J Gasterentol.  Nov; 24(11):643-50

 

Burshtyn DN,  Davidson C. (2010) Natural Killer Cell Conjugate Assay Using Two-Color Flow Cytometry.  In “Natural Killer Cell Protocols: Cellular and Molecular Methods, 2nd edition” Campbell, KS and M. Colona (Eds), Methods in Mol  Biol 612:89-96 Humana Press Inc

 

Campbell S, Hazes B,  Kvansakul M, Colman P, Barry M. (2010) Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. J Biol Chem 285:4695-4708

 

Clarke D, Gowrishankar M, Etches P, Lee BE, Robinson JR. (2010) Management and outcome of positive urine cultures in a neonatal intensive care unit. J  Infection & Public Health 3:152-8

 

Courgnaud V, Battini J-L, Sitbon M, Mason A. (2010) Mouse retroviruses and chronic fatigue syndrome: does X (or P) mark the spot? PNA  Sci. 107;15666 -15667

 

Dar A, Nichani A, Lai K, Potter A, Gerdts V, Babiuk LA, Mutwiri G. (2010) All three classes of CpG ODNs up-regulate IP-10 gene in pigs. Res Vet Sci. 88: 242-250

 

Davidson C, Li N, Burshtyn DN. (2010) LILRB1 polymorphism and surface phenotype of natural killer cells.  Human Immunol  71:942

 

Douglas D, Kawahara T, Sis B, Bond D, Fischer KP, Tyrrell DLJ, Lewis J, Kneteman NM. (2010) Therapeutic Efficacy of Human Hepatocyte Transplantation in a SCID/UPa Mouse Model with Inductible Liver Disease. PLos ONE.  Feb 18; 5(2): e9209

 

Garlapati S, Eng NF,  Wilson HL, Buchanan R, Mutwiri GK, Babiuk LA, Gerdts V.  (2010). PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice. Vaccine. 28: 8306-14

 

Hedlin PD, Cashman NR, Li L, Gupta J, Babiuk LA, Potter AA, Briebel P, Napper S. (2010) Design and delivery of a cryptic PrP© epitope for induction of PrP(Sc)-specific antibody responses. Vaccine. pp. 981-988

 

Hong C, Duit  S, Jalonen P, Out R, Scheer  L, Boyadjian R, Rodenbur  K, Foley  E, Korhone  L, Lindholm  D, Nimph  J, van Berkel T, Tontonoz  P, Zelcer N. (2010) The E3-ubiquitin ligase IDOL induces the degradation of the low-density lipoprotein receptor family members VLDLR and ApoER2. J Biol Chem,  285(26): 19720-6

 

Emamaulle JA, Edgar R, Toso C., Thiesen A, Bain V, Bigam D, Kneteman NM, Shapiro AM. (2010) Vascular endothelial growth factor expression in hepatic epithelioid hemangioendothelioma: Implications for treatment and surgical management. Liver Transpl.  Feb; 16(2):191-7

 

Eng NF,  Garlapati S, Gerdts V, Babiuk LA,  Mutwiri GK. ( 2010) PCEP enhances lgA muscosal immune responses in mice following different immunization routes with influenza virus antigens.  J Immune Based Ther Vaccines. 8: 4; doi:10.1186/1476-8518-8-4

 

Eng NF,  Garlapati S, Gerdts V, Babiuk LA,  Mutwiri GK. ( 2010) The potential of polyphosphazenes for delivery of vaccine antigens and immunotherapeutic agents.  Curr Drug Deliv. 7: 13-20

 

Facci  MR, Auray G, Buchanan R, van Kellel J, Thompson DR, Mackenzie-Dyck S, Babiuk LA, Gerdts V. (2010)
A comparison between isolated blood dendritic cells and nomocyte-derived dendritic cells in pigs. Immunol  129: 396-405

 

Ferguson BV, Ostergaard HL.  (2010) CD45 regulates thymocyte survival during development in fetal thymic organ culture.  Immunobiol,  Jun;215(6):458-65

 

Frey SE, Houghton M, Coates S, Abrignani S, Chien D, Rosa D, Pileri P, Ray R, Di Bisceglie AM, Rinella P, Hill H, Wolff MC, Schultze V, Han JH, Scharschmidt B, Belshe RB. (2010) Safety and immunogenicity of HCV E1E2 vaccine adjuvanted with MF59 administered to healthy adults. Vaccine.  Aug 31;28(38):6367-73

 

Gammon DB,  Gowrishankar B,  Duraffour S, Andrei G, Upton C, Evans DH. (2010) Vaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis.  PLoS Pathogens. 6(7):e1000984

 

Garlapati S, Eng NF, Wilson HL, Buchanan R, Mutwiri GK, Babiuk LA, Gerdts V. (2010) PCPP (poly[di(carboxylatophenoxy)-phosphazene]) microparticles co-encapsulating ovalbumin and CpG oligo-deoxynucleotides are potent enhancers of antigen specific Th1 immune responses in mice. Vaccine. 28: 8306-14

 

Hancock MH, Cliffe AR, Knipe DM, Smiley JR. (2010) Herpes Simplex Virus VP16, but not ICP0, is Required to Reduce Histone Occupancy and Enhance Acetylation on Viral Genomes in U2OS Osteosarcoma Cells. J. Virol 84: 1366-1375

 

He JS, Gong D-E, Ostergaard HL. (2010) Stored FasL, a mediator of rapid CTL-mediated killing, has a lower threshold for response than degranulation or newly synthesized FasL.  J. Immunol.  184:555-563

 

Hedlin PD, Cashman NR, Li L, Gupta J, Babiuk LA, Potter AA, Briebel P, Napper S. (2010) Design and delivery of a cryptic PrP© epitope for induction of PrP(Sc)-specific antibody responses. Vaccine. pp. 981-988

 

Hegazy SA, Wang P, Anand M, Ingham RJ, Gelebart P, Lai R. (2010). The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions. J Biol. Chem. 285(26):19813-20

 

Hirschfield G, Liu X, Han Y, Gorlov I, Xu C, Lu Y, Chen W, Juran B, Coltescu C, Mason A, Milkiewicz P, Myers R, Odin J, Luketic V, Speiciene D, Vincent C, Levy C, Gregersen P, Zhang J, Heathcote E, Lazaridis K, Amos C, Siminovitch K. (2010) Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis. Nature Genetics 42:655-657

 

Hong C, Duit S, Jalonen P, Out R, Scheer L, Boyadjian R, Rodenburg K, Foley E, Korhonen L, Lindholm D, Nimph J, van Berkel T, Tontonoz P, Zelcer N. (2010) The E3-ubiquitin ligase IDOL induces the degradation of the low-density lipoprotein receptor family members VLDLR and ApoER2. J Biol Chem. 285(26): 19720-6

 

Humar A, Morris M, Blumberg E, Freeman R, Preiksaitis J, Kiberd B, Schweitzer E, Ganz S, Caliendo A, Orlowski J, Wilson B, Kotton C, Michaels M, Kleinman S, Geier S, Murphy B, Green M, Levi M, Knoll G, Segev D.  (2010) Nucleic Acid Testing (NAT) of Organ Donors: Is the ‘Best’ Test the Right Test? A Consensus Conference Report. Am J Transplant.; 10: 889-99

 

Humar A, Lebranchu Y, Vincenti F, Blumberg EA, Punch JD, Limaye AP, Abramowicz D, Jardine AG, Voulgari AT, Ives J, Hauser IA, Peters P. (2010) The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients. Am J Transplant. 10:1228-37

 

Humar A, Limaye AP, Blumberg EA, Hauser IA, Vincenti F, Jardine AG, Abramowicz D, Ives JA, Farhan M, Peters P. (2010) Extended valganciclovir prophylaxis in D+/R- kidney transplant recipients is associated with long-term reduction in cytomegalovirus disease: two-year results of the IMPACT study. Transplant.  90:1427-31

 

Ilkow C, Weckbecker D, Maeir S, Beatch MD, Goping IS, Herrmann J, and Hobman TC. (2010) The Rubella virus Capsid inhibits mitochondrial import. J. Virol 84:119-30

 

Ilkow C, Willows S, Hobman TC. (2010) The Rubella virus capsid: A small protein with big functions. Future Microbiol 5:571-84

 

Jackel-Cram C,  Qiao L, Xiang Z, Brownlie R, Zhou Y, Babiuk  LA, Liu Q.  (2010) Hepatitis C virus genotype-3a core protein enhances sterol regulatory element binding protein-1 activity through the P13K-Akt-2 pathway.  J Gen Virol. 91: 1388-13955

 

Joyce MAJ, Tyrrell DLJ.  (2010) The Cell Biology of Hepatitis C Virus.  Microbes and Infection. Apr; 12(4):263-271

 

Kindrachuk J, Scruten E, Attah-Poko S, Bell  K, Potter  A, Babiuk LA, Griebel PJ, Napper S.  (2010)  Stability, toxicity and biological activity of host defense peptide BMAP28 and its inversed and retro-inversed isomers. Biopolymers: March 24

 

Kawahara T, Douglas DN, Lewis J, Lund G, Addison W, Tyrrell DLJ, Churchill TA, Kneteman NM.  (2010) Critical role of NK cells in the rejection of human hepatocytes after xenotransplantation into immunodeficient mice.  Transplant Int.  Published Online:  Feb 17 2010  Doi:  10.1111/j.1432-2277.2010.01063.x

 

Kawahara T, Douglas D. Lewis J, Addison W, Churchill T, Kneteman NM.  (2010) Critical role of NK cells in the rejection of transplanted human hepatocyte transplantation into SCID/Alb-uPA mice. Transplant Int. 23(9):934-42. [Epub ahead of print]

 

Kawahara T, Toso C, Douglas D, Nourbakhsa M, Lewis J, Tyrrell DL, Lund G, Churchill TA, Kneteman NM. (2010) Factors affecting hepatocyte isolation, engraftment, and replication in an in vivo model. Liver Transpl.  Aug; 16(8):974-982

 

Kindrachuk, J, Scruten E, Attah-Poko S, Bell K, Potter A, Babiuk LA, Griebel PJ, Napper S. (2010) Stability, toxicity and biological activity of host defense peptide BMAP28 and its inversed and retro-inversed isomers. Biopolymers: March 24.

 

Kleinman S, Cameron C, Custer B, Busch M, Katz L, Kralj B, Matheson I, Murphy K, Preiksaitis J, Devine D. (2010) Modelling the risk of an emerging pathogen entering the Canadian Blood Supply.  Transfusion. 50:2592-606

 

Kneteman NM, Kawahara T. Reply. Liver Transpl. 2010 Dec;16(12):1445

 

Knoll GA, Blydt-Hansen TD, Campbell P, Cantarovich M, Cole E, Fairhead T, Gill JS, Gourishankar S, Hebert D, Hodsman A, House AA, Humar A, Karpinski M, Kim SJ, Mainra R, Prasad GV Canadian Society of Transplantation and Canadian Society of Nephrology commentary on the 2009 KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Kidney Dis., 2010; 56: 219-46

 

Kotton CN, Kumar D, Caliendo AM, Asberg A, Chou S, Snydman DR, Allen U, Humar A. (2010) Transplantation Society International CMV Consensus Group. International consensus guidelines on the management of cytomegalovirus in solid organ transplantation. Transplant. 89: 779-95

 

Kraus A, Groenendyk J, Bedard K, Baldwin TA, Krause KH, Dubois-Dauphin M, Dyck J, Rosenbaum EE, Korngut L, Colley NJ, Gosgnach S, Zochodne D, Todd K, Agellon LB, Michalak M. (2010) Calnexin deficiency leads to dysmyelination. J Biol Chem. 285(24): 18928-38

 

Krishnadas DK, Ahn JS, Han J, Kumar R, Agrawal B.  (2010) Immunomodulation by hepatitis C virus-derived proteins: targeting human dendritic cells by multiple mechanisms.  Int Immunol, 22(6), 491-502

 

Krishnadas DK, Li W, Kumar R, Tyrrell DL, Agrawal B. (2010) HCV-core and NS3 antigens play disparate role in inducing regulatory or effector T cells in vivo: Implications for viral persistence or clearance.  Vaccine, 28(9), 2104-14

 

Kumar D, Husain S, Chen MH, Moussa G, Himsworth D, Manuel O, Studer S, Pakstis D, McCurry K, Doucette K, Pilewski J, Janeczko R, Humar A. (2010) A Prospective Molecular Surveillance Study Evaluating the Clinical Impact of Community-Acquired Respiratory Viruses in Lung Transplant Recipients. Transplant.  Apr 27; 89(8):1028-33

 

Kumar D, Morris MI, Kotton CN, Fischer SA, Michaels MG, Allen U, Blumberg EA, Green M, Humar A, Ison MG.  (2010) AST Infectious Diseases Community of Practice and Transplant Infectious Diseases Section of TTS. Guidance on novel influenza A/H1N1 in solid organ transplant recipients. Am J Transplant. 10: 18-25

 

Kumar D, Michaels MG Morris MI, Green M, Avery RK, Liu C, Danziger-Isakov L, Stosor V, Estabrook M, Gantt S, Marr KA, Martin S, Silveira FP, Razonable RR, Allen UD, Levi ME, Lyon GM, Bell LE, Huprikar S, Patel G, Gregg KS, Pursell K, Helmersen D, Julian KG, Shiley K, Bono B, Dharnidharka VR, Alavi G, Kalpoe JS, Shoham S, Reid GE, Humar A. (2010) American Society of Transplantation H1N1 Collaborative Study Group. Outcomes from pandemic influenza A H1N1 infection in recipients of solid-organ transplants: a multicentre cohort study. Lancet Infect Dis. 10: 521-6

 

Labiuk SL, Lobanov V, Lawman Z, Snider M, Babiuk LA, van Drunen Littel-van den Hurk S. (2010) Bovine herpesvirus-1 US3protein kinase: critical residues and involvement in the phosphorylation of VP22. J Gen Virol. 91: 1117-1126

 

Lacasse  JJ, and Schang, LM (2010) During lytic infections, Herpes Simplex Virus Type 1 DNA is in nucleoprotein complexes with the properties of unstable nucleosomes.  J Virology 84 (4): 1920-1933

 

Landi A, Yu H, Babiuk LA, van Drunen Littel-van den Hurk, S. (2010) Human dentritic cells expressing hepatitis C virus core protein display transcriptional and functional changes consistent with maturation.  J Viral Hepat. 18: 700-713

 

Lavender KJ and Kane KP. (2010) Determining ligand specificity of Ly49 receptors. Methods Mol. Biol. 612:299-311.

 

Lee BE, Mukhi S, Drews SJ.  (2010) The Association of Patient Age with Influenza A Subtype During Influenza Outbreaks.  Infection Control and Hospital Epidemiology 31:535-7

 

Lee K, Vivithanaporn P, Seimienuk R, Krentz HB, Maingat F, Gill MJ, Power C. (2010) Antiepileptic drug mediated immune benefits and clinical outcomes in HIV infection. BMC Neurol.  10:44-55

 

Li R, Fan W, Tian G, Zhu H, He L, Cai J, Huang Q, Cai Q, Li B, Bai Y, Zhang Z, Zhang Y, Wang W, Li J, Wei F, Li H, Jian M, Li J, Zhang Z, Nielsen R, Li D, Gu W, Yang Z, Xuan Z, Ryder OA, Leung FC, Zhou Y, Cao J, Sun X, Fu Y, Fang X, Guo X, Wang B, Hou R, Shen F, Mu B, Ni P, Lin R, Qian W, Wang G, Yu C, Nie W, Wang J, Wu Z, Liang H, Min J, Wu Q, Cheng S, Ruan J, Wang M, Shi Z, Wen M, Liu B, Ren X, Zheng H, Dong D, Cook K, Shan G, Zhang H, Kosiol C, Xie X, Lu Z, Zheng H, Li Y, Steiner CC, Lam TT, Lin S, Zhang Q, Li G, Tian J, Gong T, Liu H, Zhang D, Fang L, Ye C, Zhang J, Hu W, Xu A, Ren Y, Zhang G, Bruford MW, Li Q, Ma L, Guo Y, An N, Hu Y, Zheng Y, Shi Y, Li Z, Liu Q, Chen Y, Zhao J, Qu N, Zhao S, Tian F, Wang X, Wang H, Xu L, Liu X, Vinar T, Wang Y, Lam TW, Yiu SM, Liu S, Zhang H, Li D, Huang Y, Wang X, Yang G, Jiang Z, Wang J, Qin N, Li L, Li J, Bolund L, Kristiansen K, Wong GK, Olson M, Zhang X, Li S, Yang H, Wang J, Wang J.  (2010). The sequence and de novo assembly of the giant panda genome. Nature  463: 311-317

 

Lin Y-C, Evans DH (2010) Vaccinia virus particles mix inefficiently in co-infected cells and in a way that would restrict viral recombination. J. Virol. 84: 2432-43 (JV Cover, November, 2010)

 

Liu X,  Invernizzi  P, Lu Y, Kosoy R, Lu Y, Bianchi I, Podda M, Xu C, Xie G, Macciardi F, Selmi C, Lupoli S, Shigeta R, Ransom M, Lleo A, Lee A, Mason A, Myers R, Peltekian K, Ghent C, Bernuzzi F, Zuin M, Rosina F, Borghesio E, Floreani A, Lazzari R, Niro G, Andriulli A, Muratori L, Muratori P, Almasio P, Andreone P, Margotti M, Brunetto M, Coco B, Alvaro D, Bragazzi M, Marra F, Pisano A, Rigamont Ci, Colombo M, Marzioni  M, Benedetti A, Fabris L, Strazzabosco M, Portincasa P, Palmieri V, Tiribelli C, Croce L, Bruno S, Rossi S, Vinci M, Prisco C, Mattalia A, Toniutto P, Picciotto A, Galli A, Ferrari C, Colombo S, Casella G, Morini L, Caporaso N, Colli A, Spinzi G, Montanari R, Gregersen P, Heathcote E, Hirschfield G, Siminovitch K, Amos C, Gershwin M, Seldin M. (2010) Genome-wide meta-analyses identifies three loci associated with primary biliary cirrhosis Nature Genetics 42:658-660

 

Lobanov VA, Maher-Sturgess SL, Snider MG, Lawman Z, Babiuk LA, van Drunen Littel-van den Hurk S. (2010) A UL47 gene deletion mutant of bovine herpesvirus type 1 exhibits impaired growth in cell culture and lack of virulence in cattle. J Virol. 84: 445-458

 

Lobanov VA, Babiuk LA, van Drunen Littel-van den Hurk S (2010) Intracellular trafficking of VP22 in bovine herpesvirus-1 infected cells. Virol. 396: 189-202

 

Loeb M, Russell ML, Moss L, Fonseca K, Fox J, Earn DJ, Acki F, Horsman G, Van Caeseele P, Chokani K, Vooght M, Babiuk LA, Webby R, Walter SD. (2010) Effect of influenza vaccination of children on infection rates in Hutterite communities: a randomized trial. JAMA. 303: 943-950

 

Lysechko TL, Cheung SM, Ostergaard HL.  (2010) Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes.  J Biol Chem. Oct 8;285(41):31174-84

 

MacIntyre D, Miyata S T, Kitaoka M, Pukatzki S. (2010) The Vibrio cholerae type VI secretion system displays antimicrobial activity. PNAS 107: 19520-19524

 

Maingat F, Viappiani S, Zhu Y, Vivithanaporn P, Ellestad K, Holden J, Silva C, Power C. (2010) Regulation of lentivirus neurovirulence by lipopolysaccharide conditioning: suppression of CXCL10 in brain by IL-10. J Immunol. 184(3): 1566-74

 

Mapletoft JW, Latimer L, Babiuk LA, van Drunen Littel-van den Hurk, S. (2010) Intranasal immunication of mice with a bovine respiratory syncytial virus vaccine induces superior immunity and protection compared to those by subcutaneous delivery or combinations of intranasal and subcutaneous prime-boost strategies. Clin Vaccine Immunol. 17: 23-35

 

Masic A,  Lu X, Li J, Mutwiri GK, Babiuk LA, Brown EG,  Zhou Y. (2010) Immunogenicity and protective efficacy of an elastase-dependent live attenuated swine influenza virus vaccines administered intranasally in pigs. Vaccine. 28: 7098-108

 

Mattison K, Grudeski E, Auk B, Brassard J, Charest H, Dust K, Gubbay J, Hatchette TF, Houde A, Jean J, Jones T, Lee BE, Mamiya H, McDonald R, Mykytczuk O, Pang X, Petrich A, Plante D, Ritchie G, Wong J, Booth TF. (2010) Analytical performance of norovirus real-time RT-PCRdetection protocols in Canadian laboratories.  J Clin Virol. Nov 9. [Epub ahead of print]

 

Mitchell J M, Mansfeld J, Capitanio J, Kutay U, Wozniak RW. (2010) Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane. J Cell Biol. 191:505-21

 

Miyata ST, Kitaoka M, Wieteska L, Frech C, Chan F, Pukatzki S. (2010) The Vibrio cholerae type VI secretion system: evaluating its role in the human disease cholera. Frontiers in Cellular & Infection Microbiol 1: Article 117, 1-7

 

Mohajerani SA, Nourbakhsh M, Cadili A, Lakey JRT, Kneteman NM.  (2010) Transplant of Primary Human Hepatocytes Co-Cultured with Bone Marrow Stromal Cells to SCID Alb-uPA Mice. Cell Medicine: Part B of Cell Transpl. Vol 1:81-92

 

Molinari M, Berman K, Meeberg G, Shapiro AMJ, Bigam D, Trotter JF, Kneteman N. (2010) Multicentric Outcome Analysis of Sirolimus Based Immunosuppression in 252 Cadaveric Liver Transplant Patients. Transpl Int. 23(2):155-68. 2009  Sep 18. [Epub ahead of print]

 

Montano-Loza AJ, Wasilenko ST, Bintner J, Mason AL. (2010) Cyclosporine A protects against primary biliary cirhosis recurrence after liver transplantation. AJ Transplant 10;852-858

 

Montano-Loza AJ, Wasilenko ST, Bintner J, Mason AL. (2010) Cyclosporine A inhibits in vitro replication of betaretrovirus associated with primary biliary cirhosis. Liver Int  30;871-877

 

Mukhi SN, May-Hadford J, Plitt S, Preiksaitis JK, Lee BE.  (2010) DIAL: A Platform for real-time Laboratory Surveillance.  Online J Public Health Informatics. 2(3):1-10

 

Na H, Huisman W, Ellestad KK, Phillips TR, Power C.  (2010) Domain- and nucleotide-specific Rev response element regulation of feline immunodeficiency virus production. Virol.  404(2):246-60

 

Nichani AK,  Dar MA,  Mirakhur KK,  Drieg AM,  Booth JS,  Townsend  HG,  Potter AA, Babiuk LA, Mutwiri GK, (2010) Subcutaneous but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs.  Comp Immunol Microbiol Infect Dis. 33: e111-7

 

Noorbakhsh F, Ramachandran R, Barsby N, Ellestad KK, LeBlanc A, Dickie P, Baker G, Hollenberg MD, Cohen E, Power C. (2010) MicroRNA profiling reveals new aspects of HIV neurodegeneration: Caspace-6 regulates astrocyte survival. FASEB J. 24(6):1799-812

 

Mitchell  JM, Mansfeld  J, Capitanio J, Kutay U,  Wozniak RW (2010) Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane.  Citation: J Cell Biol. November 2010;191(3):505-21

 

Pang XL, Preiksaitis JK, Wong S, Li V, Lee BE. (2010) Influence of Novel Norovirus GII.4 Variants on Gastroenteritis Outbreak Dynamics in Alberta and the Northern Territories, Canada between 2000 and 2008. PLoS One. 5(7):e11599

 

Rachlis A, Harris M, Lalonde R, Shafran SD, Tremblay C, Wainberg MA, Walmsley S. (2010) Canadian consensus guidelines for the optimal use of maraviroc in the treatment of HIV-infected adults. Can J Infect Dis Med Microbiol 21(4):159-72

 

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